ZBTB8A and TNIP3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		ZBTB8A	TNIP3
Description		zinc finger and BTB domain containing 8A	TNFAIP3 interacting protein 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Cytoplasm Cytosol
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Coactivator Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding	Protein Binding Polyubiquitin Modification-dependent Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II	MyD88-independent Toll-like Receptor Signaling Pathway Regulation Of Transcription By RNA Polymerase II Inflammatory Response Toll-like Receptor 4 Signaling Pathway Regulation Of Canonical NF-kappaB Signal Transduction Negative Regulation Of Canonical NF-kappaB Signal Transduction Cellular Response To Lipopolysaccharide
Pathways			Ovarian tumor domain proteases
Drugs
Diseases
GWAS			Breast cancer ( 23468962) Multiple sclerosis ( 31604244)
Interacting Genes		76 interacting genes: ACOT12 AEN AP1M1 AP2M1 ARMC7 ARMCX1 BAZ2B BLK BYSL CBX8 CCDC33 CDC37 CDKL3 CEP70 CSNK1D CWF19L2 DDX6 DVL2 DVL3 EHHADH EIF1AD EP300 FAM161A FAM90A1 FXR2 GPATCH2L HIC2 JRK KAT5 KAT7 KIF5B KIF9 KIFC3 LGALS14 LMO3 LNX1 MCM10 MFAP1 MRPL11 MYO15B NTAQ1 PAXIP1 PIAS2 PRKAA2 PRPF3 PRR34 PSMC1 RAD23A RPL9 SDCBP SYT6 TCEA2 TNIP3 TRIM41 UBE2I YES1 ZBTB17 ZBTB24 ZBTB48 ZBTB49 ZCCHC10 ZGPAT ZMAT2 ZNF138 ZNF250 ZNF276 ZNF329 ZNF35 ZNF408 ZNF417 ZNF438 ZNF497 ZNF572 ZNF587 ZNF648 ZNF837	25 interacting genes: CCN3 CYSRT1 DAZAP2 FAM161A KPNA3 KRT40 KRTAP10-3 KRTAP10-8 LITAF LZTS2 MAGEA2 MAGEA2B MTUS2 NBPF19 NOTCH2NLA NTAQ1 PIBF1 PLSCR3 TAX1BP1 TCEANC TNIP1 TRIM55 TRIM63 UBC ZBTB8A
Entrez ID		653121	79931
HPRD ID		18902	16268
Ensembl ID		ENSG00000160062	ENSG00000050730
Uniprot IDs		D3DPQ1 Q96BR9	Q96KP6
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription By RNA Polymerase II Zinc Ion Binding Nucleus Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Protein Binding Regulation Of RNA Metabolic Process DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Gene Expression Metal Ion Binding Regulation Of Macromolecule Biosynthetic Process Peptide Butyryltransferase Activity Peptide 2-hydroxyisobutyryltransferase Activity Peptide Crotonyltransferase Activity Histone H4 Acetyltransferase Activity Peptidyl-lysine Acetylation Regulation Of Macromolecule Metabolic Process Peptide Lactyltransferase (CoA-dependent) Activity Histone Acetyltransferase Complex Nucleoplasm Histone Acetyltransferase Activity Regulation Of Tubulin Deacetylation Lipid Droplet Disassembly Protein Acetylation Organelle Disassembly Regulation Of Metabolic Process Positive Regulation Of Neuron Projection Arborization Frizzled Binding Histone H3 Acetyltransferase Activity Internal Peptidyl-lysine Acetylation Histone H4K16 Acetyltransferase Activity Identical Protein Binding Internal Protein Amino Acid Acetylation Phosphatidylethanolamine Biosynthetic Process Regulation Of Protein Deacetylation Kinesin Complex Signal Transduction By P53 Class Mediator	Negative Regulation Of Protein Acetylation Negative Regulation Of Protein Sumoylation Positive Regulation Of Ubiquitin-protein Transferase Activity
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