DDIT3 and FOSL2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		DDIT3	FOSL2
Gene Name		DNA-damage-inducible transcript 3	FOS-like antigen 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Late Endosome Cytosol CHOP-C/EBP Complex	Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Transcription Factor Binding Transcription Regulatory Region DNA Binding Protein Heterodimerization Activity	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding Double-stranded DNA Binding Sequence-specific DNA Binding Transcription Factor Activity
	Biological Process	Blood Vessel Maturation Regulation Of Transcription, DNA-templated Cellular Response To DNA Damage Stimulus ER Overload Response Response To Unfolded Protein Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Cell Cycle Arrest Wnt Signaling Pathway Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Interleukin-8 Production Response To Endoplasmic Reticulum Stress Response To Starvation MRNA Transcription From RNA Polymerase II Promoter Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Neuron Apoptotic Process Regulation Of DNA-templated Transcription In Response To Stress Cellular Protein Metabolic Process Regulation Of Transcription Involved In Anterior/posterior Axis Specification Cell Redox Homeostasis Negative Regulation Of Myoblast Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Release Of Sequestered Calcium Ion Into Cytosol Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Negative Regulation Of Determination Of Dorsal Identity	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Female Pregnancy Cell Death Response To Mechanical Stimulus Response To Progesterone Cellular Response To Hormone Stimulus Response To Drug Response To Morphine Positive Regulation Of Fibroblast Proliferation Response To Corticosterone Response To CAMP
Pathways		ATF4 activates genes PERK regulates gene expression ATF6-alpha activates chaperones ATF6-alpha activates chaperone genes Unfolded Protein Response (UPR)
Drugs
Diseases
GWAS			Inflammatory bowel disease ( 23128233) Type 1 diabetes ( 21980299)
Protein-Protein Interactions		57 interactors: AMOTL2 ATF2 ATF3 ATF4 ATPAF2 BACH1 BACH2 BATF BATF2 BATF3 C11orf30 C14orf80 CCDC153 CDK6 CEBPB CEBPE CEBPG CREB3 CREB3L1 CSNK2A1 DBP DGCR2 EP300 EPAS1 F2 FOS FOSL1 FOSL2 GIPC1 GP1BA HOXA5 HSD17B14 IKBKG JUN JUNB JUND KPNA2 LMO2 MAFF MAFG MAPK14 MCMBP NFIL3 PICALM POLR1D RAI1 RPS3A SNAPC5 SPOP SRA1 SSX3 TNFSF12 TRIB3 VPS37C ZBTB25 ZC3H14 ZSCAN31	13 interactors: CREB5 DDIT3 DNAJA3 EP300 FHL3 GMCL1 GOPC JUN JUNB JUND LUZP4 SRA1 TRAF1
Entrez ID		1649	2355
HPRD ID		00529	03343
Ensembl ID		ENSG00000175197
Uniprot IDs		P35638 Q53YD1	P15408 Q9H5M2
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Biosynthetic Process Transcription, DNA-templated Gene Expression RNA Metabolic Process Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of RNA Metabolic Process Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Immune System Process Cellular Metabolic Process Regulation Of Cellular Process Response To Endoplasmic Reticulum Stress Myeloid Cell Differentiation Myeloid Leukocyte Differentiation Hemopoiesis Response To Stress Immune System Development Developmental Process Response To Other Organism Leukocyte Differentiation Anatomical Structure Development Response To Biotic Stimulus Circadian Rhythm Cellular Response To Stress Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Defense Response Toll-like Receptor 5 Signaling Pathway Organ Development Toll-like Receptor 10 Signaling Pathway System Development	Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Developmental Process Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Cellular Response To Calcium Ion Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription In Response To Stress Apoptotic Process Programmed Cell Death Positive Regulation Of Transcription From RNA Polymerase II Promoter Cell Death Death Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation By Host Of Viral Transcription Positive Regulation Of Transcription, DNA-templated Response To Calcium Ion Regulation Of Metabolic Process Cellular Response To Metal Ion Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Cellular Response To Inorganic Substance Positive Regulation Of Gene Expression Cell Differentiation RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Response To Endoplasmic Reticulum Stress Cellular Macromolecule Biosynthetic Process Anatomical Structure Development Circadian Rhythm Positive Regulation Of Cellular Metabolic Process Macromolecule Biosynthetic Process Response To Abiotic Stimulus Interaction With Symbiont Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Response To Mechanical Stimulus Positive Regulation Of Viral Transcription Negative Regulation Of Biosynthetic Process RNA Metabolic Process Positive Regulation Of Neuron Apoptotic Process Rhythmic Process Nucleobase-containing Compound Metabolic Process Regulation Of Apoptotic Process Positive Regulation Of Metabolic Process Aging
Tagcloud ?		a5 aapoaii advance aggregated amyloid amyloidosis apoa2c apolipoprotein atf4 atf6 atg5 deposition deposits doi eif2ak3 extracellularly fibril fibrils hspa5 intravenously labinvest online p1 protecting publication r1 senile unfolded xbp1s	acetylation antigen ap belongs beta1 correlates diverse facilitates fra indicates interacts little mechanistically migration nsclc p300 pathological physiological processes promotes regulate regulates show signalling smad3 suggests summary tgf
Tagcloud (Difference) ?		a5 aapoaii advance aggregated amyloid amyloidosis apoa2c apolipoprotein atf4 atf6 atg5 deposition deposits doi eif2ak3 extracellularly fibril fibrils hspa5 intravenously labinvest online p1 protecting publication r1 senile unfolded xbp1s	acetylation antigen ap belongs beta1 correlates diverse facilitates fra indicates interacts little mechanistically migration nsclc p300 pathological physiological processes promotes regulate regulates show signalling smad3 suggests summary tgf
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