FOSL2 and FHL3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		FOSL2	FHL3
Gene Name		FOS-like antigen 2	four and a half LIM domains 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm	Stress Fiber Nucleus Focal Adhesion Z Disc
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding Double-stranded DNA Binding Sequence-specific DNA Binding Transcription Factor Activity	Actin Binding Zinc Ion Binding
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Female Pregnancy Cell Death Response To Mechanical Stimulus Response To Progesterone Cellular Response To Hormone Stimulus Response To Drug Response To Morphine Positive Regulation Of Fibroblast Proliferation Response To Corticosterone Response To CAMP	Muscle Organ Development Actin Cytoskeleton Organization
Pathways
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233) Type 1 diabetes ( 21980299)
Protein-Protein Interactions		13 interactors: CREB5 DDIT3 DNAJA3 EP300 FHL3 GMCL1 GOPC JUN JUNB JUND LUZP4 SRA1 TRAF1	88 interactors: A1CF ACTB ADAM15 ADAMTSL4 AIMP2 AMBP C14orf105 C9orf116 CDC25B CDC42EP1 CNNM3 CORO1A CSF1 CTBP2 DCDC2B E2F8 EFCAB12 EPHA10 EPM2AIP1 FAM154A FAM71C FAM90A1 FBXL18 FHL2 FHL5 FOSL2 GATA2 GCM2 HIPK1 HYAL2 ITGA7 KIRREL2 KLF3 KLF8 KRTAP12-1 KRTAP12-2 KTI12 LASP1 LMO2 LNX1 MAPK1 MED15 MPZL1 MRPL27 MYBPC1 MYBPHL MZF1 NPRL3 P4HA2 PAK7 PATL1 PHC2 PHF21A PLEKHF2 PPIG PTPN6 QRICH1 RAD21 RBM42 RFX3 RFX6 RHEBL1 RNMTL1 SAP30BP SLAIN1 SLC25A46 SLC44A3 SMAD2 SMAD3 SMAD4 SNRPG SREBF2 SRF TMX3 TRAF3IP2 TRIM27 TRIP6 TRO TTLL10 TYK2 TYMSOS UBE2I UBE2Q1 WNK1 YPEL3 ZNF417 ZNF512B ZNRD1
Entrez ID		2355	2275
HPRD ID		03343	09101
Ensembl ID			ENSG00000183386
Uniprot IDs		P15408 Q9H5M2	Q13643 Q96C98
PDB IDs			1WYH 2CUQ 2EHE
Enriched GO Terms of Interacting Partners?		Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Developmental Process Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Cellular Response To Calcium Ion Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription In Response To Stress Apoptotic Process Programmed Cell Death Positive Regulation Of Transcription From RNA Polymerase II Promoter Cell Death Death Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation By Host Of Viral Transcription Positive Regulation Of Transcription, DNA-templated Response To Calcium Ion Regulation Of Metabolic Process Cellular Response To Metal Ion Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Cellular Response To Inorganic Substance Positive Regulation Of Gene Expression Cell Differentiation RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Response To Endoplasmic Reticulum Stress Cellular Macromolecule Biosynthetic Process Anatomical Structure Development Circadian Rhythm Positive Regulation Of Cellular Metabolic Process Macromolecule Biosynthetic Process Response To Abiotic Stimulus Interaction With Symbiont Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Response To Mechanical Stimulus Positive Regulation Of Viral Transcription Negative Regulation Of Biosynthetic Process RNA Metabolic Process Positive Regulation Of Neuron Apoptotic Process Rhythmic Process Nucleobase-containing Compound Metabolic Process Regulation Of Apoptotic Process Positive Regulation Of Metabolic Process Aging	RNA Metabolic Process Transcription, DNA-templated Gene Expression RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Heterocycle Metabolic Process Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process SMAD Protein Complex Assembly Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Regulation Of Cellular Process Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Cellular Metabolic Process Negative Regulation Of Cellular Metabolic Process Cell Differentiation Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Cell Proliferation Negative Regulation Of RNA Biosynthetic Process Tissue Development Positive Regulation Of Cellular Metabolic Process Cell Death Death Multicellular Organismal Homeostasis Positive Regulation Of Epithelial To Mesenchymal Transition Endoderm Development Negative Regulation Of Cell Growth Embryonic Organ Development Positive Regulation Of Metabolic Process Primary MiRNA Processing Organ Development Apoptotic Process
Tagcloud ?		acetylation antigen ap belongs beta1 correlates diverse facilitates fra indicates interacts little mechanistically migration nsclc p300 pathological physiological processes promotes regulate regulates show signalling smad3 suggests summary tgf	accompanied adhesion anchorage antiproliferative arrest b1 cip1 downregulated g1 g2 half implicated interfering knockdown lim marked marker member mobility p21 progression regulator sirna suppressed thereby transduction unclear waf1
Tagcloud (Difference) ?		acetylation antigen ap belongs beta1 correlates diverse facilitates fra indicates interacts little mechanistically migration nsclc p300 pathological physiological processes promotes regulate regulates show signalling smad3 suggests summary tgf	accompanied adhesion anchorage antiproliferative arrest b1 cip1 downregulated g1 g2 half implicated interfering knockdown lim marked marker member mobility p21 progression regulator sirna suppressed thereby transduction unclear waf1
Tagcloud (Intersection) ?