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DDIT3 and CEBPG
Number of citations of the paper that reports this interaction (PMID
16189514
)
699
Data Source:
HPRD
(two hybrid)
DDIT3
CEBPG
Gene Name
DNA-damage-inducible transcript 3
CCAAT/enhancer binding protein (C/EBP), gamma
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Late Endosome
Cytosol
CHOP-C/EBP Complex
Nucleus
Nucleoplasm
Molecular Function
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription
DNA Binding
Sequence-specific DNA Binding Transcription Factor Activity
Transcription Corepressor Activity
Protein Binding
Transcription Factor Binding
Transcription Regulatory Region DNA Binding
Protein Heterodimerization Activity
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription
DNA Binding
Double-stranded DNA Binding
Protein Binding
Transcription Factor Binding
Sequence-specific DNA Binding
Protein Heterodimerization Activity
Biological Process
Blood Vessel Maturation
Regulation Of Transcription, DNA-templated
Cellular Response To DNA Damage Stimulus
ER Overload Response
Response To Unfolded Protein
Activation Of Signaling Protein Activity Involved In Unfolded Protein Response
Cell Cycle Arrest
Wnt Signaling Pathway
Endoplasmic Reticulum Unfolded Protein Response
Positive Regulation Of Interleukin-8 Production
Response To Endoplasmic Reticulum Stress
Response To Starvation
MRNA Transcription From RNA Polymerase II Promoter
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Positive Regulation Of Neuron Apoptotic Process
Regulation Of DNA-templated Transcription In Response To Stress
Cellular Protein Metabolic Process
Regulation Of Transcription Involved In Anterior/posterior Axis Specification
Cell Redox Homeostasis
Negative Regulation Of Myoblast Differentiation
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Release Of Sequestered Calcium Ion Into Cytosol
Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
Negative Regulation Of Canonical Wnt Signaling Pathway
Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress
Negative Regulation Of Determination Of Dorsal Identity
Liver Development
Transcription, DNA-templated
Regulation Of Transcription From RNA Polymerase II Promoter
Immune Response
MRNA Metabolic Process
B Cell Differentiation
Natural Killer Cell Mediated Cytotoxicity
Enucleate Erythrocyte Differentiation
Positive Regulation Of DNA Binding
Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Positive Regulation Of Interferon-gamma Biosynthetic Process
Positive Regulation Of DNA Repair
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Pathways
ATF4 activates genes
PERK regulates gene expression
ATF6-alpha activates chaperones
ATF6-alpha activates chaperone genes
Unfolded Protein Response (UPR)
Drugs
Diseases
GWAS
Inflammatory bowel disease (
23128233
)
Protein-Protein Interactions
57 interactors:
AMOTL2
ATF2
ATF3
ATF4
ATPAF2
BACH1
BACH2
BATF
BATF2
BATF3
C11orf30
C14orf80
CCDC153
CDK6
CEBPB
CEBPE
CEBPG
CREB3
CREB3L1
CSNK2A1
DBP
DGCR2
EP300
EPAS1
F2
FOS
FOSL1
FOSL2
GIPC1
GP1BA
HOXA5
HSD17B14
IKBKG
JUN
JUNB
JUND
KPNA2
LMO2
MAFF
MAFG
MAPK14
MCMBP
NFIL3
PICALM
POLR1D
RAI1
RPS3A
SNAPC5
SPOP
SRA1
SSX3
TNFSF12
TRIB3
VPS37C
ZBTB25
ZC3H14
ZSCAN31
22 interactors:
ATF2
ATF3
ATF4
ATF5
BATF
BATF2
BATF3
CEBPA
CEBPB
CEBPD
CEBPE
CREB3
CREB3L3
DBP
DDIT3
FOS
FOSL1
GTF2F2
JUN
MLLT6
PLAU
POLR2M
Entrez ID
1649
1054
HPRD ID
00529
00738
Ensembl ID
ENSG00000175197
ENSG00000153879
Uniprot IDs
P35638
Q53YD1
P53567
PDB IDs
Enriched GO Terms of Interacting Partners
?
RNA Biosynthetic Process
Transcription, DNA-templated
Gene Expression
RNA Metabolic Process
Transcription From RNA Polymerase II Promoter
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Regulation Of Gene Expression
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Cellular Nitrogen Compound Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of RNA Metabolic Process
Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Regulation Of Metabolic Process
Positive Regulation Of Gene Expression
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Cellular Biosynthetic Process
Positive Regulation Of Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Immune System Process
Cellular Metabolic Process
Regulation Of Cellular Process
Response To Endoplasmic Reticulum Stress
Myeloid Cell Differentiation
Myeloid Leukocyte Differentiation
Hemopoiesis
Response To Stress
Immune System Development
Developmental Process
Response To Other Organism
Leukocyte Differentiation
Anatomical Structure Development
Response To Biotic Stimulus
Circadian Rhythm
Cellular Response To Stress
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Defense Response
Toll-like Receptor 5 Signaling Pathway
Organ Development
Toll-like Receptor 10 Signaling Pathway
System Development
Transcription From RNA Polymerase II Promoter
RNA Biosynthetic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription, DNA-templated
RNA Metabolic Process
Macromolecule Biosynthetic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Macromolecule Biosynthetic Process
Gene Expression
Positive Regulation Of Gene Expression
Regulation Of Transcription, DNA-templated
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of Nucleic Acid-templated Transcription
Cellular Macromolecule Biosynthetic Process
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Positive Regulation Of Transcription, DNA-templated
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Biosynthetic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Response To Endoplasmic Reticulum Stress
Positive Regulation Of Cellular Metabolic Process
Response To External Stimulus
Myeloid Leukocyte Differentiation
Response To Biotic Stimulus
Regulation Of Metabolic Process
Positive Regulation Of Metabolic Process
Response To Stress
Endoplasmic Reticulum Unfolded Protein Response
Cellular Response To Unfolded Protein
ER-nucleus Signaling Pathway
Cellular Response To Topologically Incorrect Protein
Myeloid Cell Differentiation
Response To Unfolded Protein
Response To Other Organism
Organ Development
Cellular Response To Stress
Leukocyte Differentiation
Defense Response
Myeloid Dendritic Cell Differentiation
System Development
Myeloid Dendritic Cell Activation
Cellular Response To Organic Substance
Response To Extracellular Stimulus
Cellular Metabolic Process
Tagcloud
?
a5
aapoaii
advance
aggregated
amyloid
amyloidosis
apoa2c
apolipoprotein
atf4
atf6
atg5
deposition
deposits
doi
eif2ak3
extracellularly
fibril
fibrils
hspa5
intravenously
labinvest
online
p1
protecting
publication
r1
senile
unfolded
xbp1s
Tagcloud (Difference)
?
a5
aapoaii
advance
aggregated
amyloid
amyloidosis
apoa2c
apolipoprotein
atf4
atf6
atg5
deposition
deposits
doi
eif2ak3
extracellularly
fibril
fibrils
hspa5
intravenously
labinvest
online
p1
protecting
publication
r1
senile
unfolded
xbp1s
Tagcloud (Intersection)
?