DDIT3 and JUNB

Number of citations of the paper that reports this interaction (PMID 23661758)
2

Data Source:
BioGRID (fluorescent resonance energy transfer)

		DDIT3	JUNB
Gene Name		DNA-damage-inducible transcript 3	jun B proto-oncogene
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Late Endosome Cytosol CHOP-C/EBP Complex	Chromatin Nucleoplasm
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Transcription Factor Binding Transcription Regulatory Region DNA Binding Protein Heterodimerization Activity	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA Binding Double-stranded DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding
	Biological Process	Blood Vessel Maturation Regulation Of Transcription, DNA-templated Cellular Response To DNA Damage Stimulus ER Overload Response Response To Unfolded Protein Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Cell Cycle Arrest Wnt Signaling Pathway Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Interleukin-8 Production Response To Endoplasmic Reticulum Stress Response To Starvation MRNA Transcription From RNA Polymerase II Promoter Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Neuron Apoptotic Process Regulation Of DNA-templated Transcription In Response To Stress Cellular Protein Metabolic Process Regulation Of Transcription Involved In Anterior/posterior Axis Specification Cell Redox Homeostasis Negative Regulation Of Myoblast Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Release Of Sequestered Calcium Ion Into Cytosol Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Negative Regulation Of Determination Of Dorsal Identity	Vasculogenesis Osteoblast Differentiation Trophectodermal Cell Differentiation Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transforming Growth Factor Beta Receptor Signaling Pathway Response To Light Stimulus Response To Mechanical Stimulus Gene Expression Osteoclast Differentiation Response To Progesterone Cellular Response To Hormone Stimulus Osteoblast Proliferation Response To Cytokine Response To Drug Response To Peptide Hormone Positive Regulation Of Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Decidualization Response To Corticosterone Response To CAMP Regulation Of Cell Cycle Embryonic Process Involved In Female Pregnancy Labyrinthine Layer Blood Vessel Development Cellular Response To Calcium Ion Negative Regulation Of Nucleic Acid-templated Transcription
Pathways		ATF4 activates genes PERK regulates gene expression ATF6-alpha activates chaperones ATF6-alpha activates chaperone genes Unfolded Protein Response (UPR)	Loss of Function of TGFBR2 in Cancer TGFBR2 MSI Frameshift Mutants in Cancer SMAD2/3 Phosphorylation Motif Mutants in Cancer Loss of Function of SMAD2/3 in Cancer TGFBR2 Kinase Domain Mutants in Cancer Loss of Function of SMAD4 in Cancer SMAD2/3 MH2 Domain Mutants in Cancer TGFBR1 KD Mutants in Cancer TGFBR1 LBD Mutants in Cancer SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer Loss of Function of TGFBR1 in Cancer Generic Transcription Pathway Signaling by TGF-beta Receptor Complex Signaling by TGF-beta Receptor Complex in Cancer SMAD4 MH2 Domain Mutants in Cancer
Drugs
Diseases
GWAS
Protein-Protein Interactions		57 interactors: AMOTL2 ATF2 ATF3 ATF4 ATPAF2 BACH1 BACH2 BATF BATF2 BATF3 C11orf30 C14orf80 CCDC153 CDK6 CEBPB CEBPE CEBPG CREB3 CREB3L1 CSNK2A1 DBP DGCR2 EP300 EPAS1 F2 FOS FOSL1 FOSL2 GIPC1 GP1BA HOXA5 HSD17B14 IKBKG JUN JUNB JUND KPNA2 LMO2 MAFF MAFG MAPK14 MCMBP NFIL3 PICALM POLR1D RAI1 RPS3A SNAPC5 SPOP SRA1 SSX3 TNFSF12 TRIB3 VPS37C ZBTB25 ZC3H14 ZSCAN31	37 interactors: APLP2 ATF3 ATF4 BATF BATF2 BATF3 BCL6 BDNF BRCA1 C19orf68 DDIT3 EP300 ESR1 FOS FOSB FOSL1 FOSL2 HOXA7 JDP2 MAP2 MAPK14 MAPK6 MAPK8 MAPK9 NEU1 NFE2L1 NINL PKIA SAT1 SET SMAD3 SMAD4 SMURF1 TCERG1 TDG USP24 ZNF595
Entrez ID		1649	3726
HPRD ID		00529	01303
Ensembl ID		ENSG00000175197	ENSG00000171223
Uniprot IDs		P35638 Q53YD1	P17275 Q5U079
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Biosynthetic Process Transcription, DNA-templated Gene Expression RNA Metabolic Process Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of RNA Metabolic Process Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Immune System Process Cellular Metabolic Process Regulation Of Cellular Process Response To Endoplasmic Reticulum Stress Myeloid Cell Differentiation Myeloid Leukocyte Differentiation Hemopoiesis Response To Stress Immune System Development Developmental Process Response To Other Organism Leukocyte Differentiation Anatomical Structure Development Response To Biotic Stimulus Circadian Rhythm Cellular Response To Stress Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Defense Response Toll-like Receptor 5 Signaling Pathway Organ Development Toll-like Receptor 10 Signaling Pathway System Development	Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Regulation Of Gene Expression Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Metabolic Process Biosynthetic Process RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Cellular Response To Organic Substance Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cellular Protein Metabolic Process Cellular Metabolic Process Regulation Of Protein Metabolic Process Response To Organic Substance Positive Regulation Of Transcription From RNA Polymerase II Promoter Multicellular Organismal Development Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Gene Expression Response To External Stimulus Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Response To Lipid Response To Mechanical Stimulus Positive Regulation Of Transcription, DNA-templated Anatomical Structure Development Response To Abiotic Stimulus Developmental Process Response To Corticosterone Response To Biotic Stimulus Positive Regulation Of Macromolecule Biosynthetic Process Cellular Response To Stress Response To Mineralocorticoid Positive Regulation Of Cellular Biosynthetic Process
Tagcloud ?		a5 aapoaii advance aggregated amyloid amyloidosis apoa2c apolipoprotein atf4 atf6 atg5 deposition deposits doi eif2ak3 extracellularly fibril fibrils hspa5 intravenously labinvest online p1 protecting publication r1 senile unfolded xbp1s	accumulated amplified clones delay differentiate differentiative ectopic epo erythroid erythropoietin evaluating g418 grow heavy introduced lg modifies modify neither plasmacytoma proliferated proliferative providing responsive retrovirally stat5 tepc transduced varied
Tagcloud (Difference) ?		a5 aapoaii advance aggregated amyloid amyloidosis apoa2c apolipoprotein atf4 atf6 atg5 deposition deposits doi eif2ak3 extracellularly fibril fibrils hspa5 intravenously labinvest online p1 protecting publication r1 senile unfolded xbp1s	accumulated amplified clones delay differentiate differentiative ectopic epo erythroid erythropoietin evaluating g418 grow heavy introduced lg modifies modify neither plasmacytoma proliferated proliferative providing responsive retrovirally stat5 tepc transduced varied
Tagcloud (Intersection) ?