ZNF135 and SCNM1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZNF135	SCNM1
Description		zinc finger protein 135	sodium channel modifier 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Spliceosomal Complex Nuclear Speck
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding Zinc Ion Binding Enzyme Binding Metal Ion Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Cytoskeleton Organization Regulation Of Anatomical Structure Morphogenesis Regulation Of Cell Morphogenesis	Alternative MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing
Pathways		Generic Transcription Pathway
Drugs
Diseases
GWAS
Interacting Genes		10 interacting genes: ANKS1A ANXA7 CDKN1A GADD45A GSK3B LMO4 RAP1B RCC1 SCNM1 WWOX	179 interacting genes: ADAMTSL4 AKAP9 AVPI1 AXIN2 BACH2 BEND7 BLZF1 CALCOCO2 CARD10 CARD9 CBY2 CCDC136 CCDC28B CCDC33 CCDC74B CCDC85B CDR2 CDR2L CEP44 CEP70 CEP76 CHIC2 CIB3 COG6 CTDSP1 CYSRT1 CYTIP DRC4 DVL2 EZHIP FAM161A FAM228A FANCL FHL2 FHL5 FNDC11 FRS3 FSD2 GIGYF1 GOLGA2 GOLGA6L9 GPRASP3 HAP1 HMBOX1 HMG20A HOMER3 HOMEZ HOOK2 HSF2BP IKZF1 IKZF3 INCA1 IRAK1BP1 JAKMIP1 KANK2 KATNBL1 KIFC3 KLF15 KRT27 KRT31 KRT33B KRT34 KRT35 KRT38 KRT39 KRT40 KRT75 KRTAP1-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP5-9 LCN2 LDOC1 LHX1 LHX3 LIMS1 LNX1 LNX2 LRP2BP LZTS1 LZTS2 MCM6 MDFI MEOX2 MID2 MIPOL1 MKRN3 MORN3 MRPL28 MSS51 MTUS2 MYLIP MYO1F NAB2 NAP1L2 NBPF19 NDUFB7 NFKBID NOTCH2NLA NUTM1 PBX4 PDE4DIP PDLIM7 PFDN5 PIBF1 PICK1 PIH1D1 PLSCR1 PNMA1 PNMA2 PPP1R16A PPP1R16B PRDM14 PRNP PRR5L PSTPIP1 RBAK RBM11 RBM48 RDM1 REL RHOH RINT1 RORB RPGRIP1 RPH3AL SMARCD1 SORBS3 SSX2IP STX11 STX19 SYCE1 TAX1BP1 TFIP11 TLE5 TNNI1 TP53BP2 TRAF1 TRAF2 TRIB3 TRIM10 TRIM23 TRIM27 TRIM37 TRIM42 TRIM54 TTC23L UBXN11 USH1G USHBP1 VIM VMAC VPS52 VWC2 ZBTB1 ZBTB14 ZDHHC17 ZGPAT ZIM2 ZMAT1 ZMYND12 ZNF135 ZNF19 ZNF20 ZNF202 ZNF438 ZNF511 ZNF526 ZNF547 ZNF552 ZNF641 ZNF688 ZNF76 ZNF774 ZNF829 ZRANB1
Entrez ID		7694	79005
HPRD ID		07242	12162
Ensembl ID		ENSG00000176293	ENSG00000163156
Uniprot IDs		B4DLZ7 P52742 Q8N9M3	Q9BWG6
PDB IDs			7DVQ 8Y7E
Enriched GO Terms of Interacting Partners?		Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Phase Transition Negative Regulation Of Catalytic Activity Cell Cycle Phase Transition Positive Regulation Of Programmed Cell Death Regulation Of Catalytic Activity Cellular Developmental Process Regulation Of Kinase Activity Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Positive Regulation Of Reactive Oxygen Species Metabolic Process Negative Regulation Of Peptidyl-serine Phosphorylation Of STAT Protein Regulation Of Microtubule Anchoring At Centrosome Apoptotic Signaling Pathway Cellular Response To Ionizing Radiation Negative Regulation Of Protein Kinase Activity Negative Regulation Of Kinase Activity PCNA-p21 Complex Negative Regulation Of Cardiac Muscle Tissue Regeneration Superior Temporal Gyrus Development Negative Regulation Of Type B Pancreatic Cell Development Negative Regulation Of Mesenchymal Stem Cell Differentiation Negative Regulation Of Glycogen (starch) Synthase Activity Negative Regulation Of Protein Phosphorylation Signal Transduction By P53 Class Mediator Regulation Of Phosphorylation Regulation Of Protein-containing Complex Assembly Ventral Spinal Cord Interneuron Differentiation Intracellular Signal Transduction Negative Regulation Of Phosphorylation Regulation Of Cell Cycle Cellular Response To Cell-matrix Adhesion Extrinsic Apoptotic Signaling Pathway Negative Regulation Of TORC2 Signaling Negative Regulation Of Dopaminergic Neuron Differentiation Regulation Of Glycogen (starch) Synthase Activity Positive Regulation Of Kinase Activity Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Mitotic Cell Cycle Negative Regulation Of Protein-containing Complex Assembly RNA Polymerase II Transcription Regulator Complex Sulfate Binding Beta-arrestin-dependent Dopamine Receptor Signaling Pathway Response To Ionizing Radiation Regulation Of Phosphorus Metabolic Process Negative Regulation Of Phosphate Metabolic Process Oncogene-induced Cell Senescence Stress-induced Premature Senescence Signal Transduction In Response To DNA Damage Negative Regulation Of Protein Metabolic Process	Protein Binding Keratin Filament Intermediate Filament Zinc Ion Binding Intermediate Filament Organization Structural Constituent Of Skin Epidermis Identical Protein Binding Cytoskeleton Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Microtubule Binding Regulation Of RNA Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Supramolecular Fiber Organization Centrosome TORC1 Complex Assembly Structural Molecule Activity Regulation Of Transcription By RNA Polymerase II DNA Binding Cytoskeleton Organization Ubiquitin Protein Ligase Activity Negative Regulation Of Calcineurin-NFAT Signaling Cascade
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