ZNF709 and ARF6

Number of citations of the paper that reports this interaction (PubMedID 16737952)
0

Data Source:
HPRD (in vitro)

		ZNF709	ARF6
Description		zinc finger protein 709	ARF GTPase 6
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Ruffle Cytoplasm Endosome Early Endosome Golgi Apparatus Cytosol Plasma Membrane Focal Adhesion Cell Cortex Endosome Membrane Membrane Endocytic Vesicle Midbody Filopodium Membrane Early Endosome Membrane Cleavage Furrow Cell Projection Recycling Endosome Recycling Endosome Membrane Extracellular Exosome Flemming Body Presynapse Postsynapse Glutamatergic Synapse
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Zinc Ion Binding Metal Ion Binding	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity GDP Binding Thioesterase Binding Signaling Adaptor Activity
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II	Mitotic Cytokinesis Liver Development Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Cell Adhesion Nervous System Development Regulation Of Neuron Projection Development Positive Regulation Of Neuron Projection Development Protein Transport Vesicle-mediated Transport Cell Differentiation Positive Regulation Of Actin Filament Polymerization Cortical Actin Cytoskeleton Organization Endocytic Recycling Protein Localization To Cell Surface Regulation Of Rac Protein Signal Transduction Protein Localization To Endosome Negative Regulation Of Receptor-mediated Endocytosis Synaptic Vesicle Endocytosis Positive Regulation Of Protein Secretion Cell Division Regulation Of Filopodium Assembly Positive Regulation Of Keratinocyte Migration Regulation Of Dendritic Spine Development Cellular Response To Diacyl Bacterial Lipopeptide Protein Localization To Plasma Membrane Establishment Of Epithelial Cell Polarity Ruffle Assembly Hepatocyte Apoptotic Process Maintenance Of Postsynaptic Density Structure Positive Regulation Of Focal Adhesion Disassembly Erythrocyte Apoptotic Process Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Mitotic Cytokinetic Process Protein Localization To Cleavage Furrow Regulation Of Presynapse Assembly Cellular Response To Nerve Growth Factor Stimulus Negative Regulation Of Protein Localization To Cell Surface Negative Regulation Of Dendrite Development
Pathways		Generic Transcription Pathway	TBC/RABGAPs Clathrin-mediated endocytosis MET receptor recycling
Drugs			5'-Guanosine-Diphosphate-Monothiophosphate Guanosine-5'-Diphosphate Myristic acid
Diseases
GWAS			Erythema nodosum in inflammatory bowel disease ( 24487271) Ferritin levels ( 33491795)
Interacting Genes		1 interacting genes: ARF6	40 interacting genes: AGAP1 AP1B1 AP2B1 AP3B1 AP3D1 AP3S2 APP ARFIP2 ARHGAP10 ARRB1 ARRB2 ASAP1 ASAP2 ASAP3 ATP6V0C CAPN1 CHRM3 CLTC CYTH1 CYTH2 EXOC5 EZR FILNC1 HTR2A IKBKG ITSN1 MEOX2 MT2A PALS1 PIP5K1A PIP5K1C PLD1 RAB11A RAB11FIP3 RAB11FIP4 RAB11FIP5 SMAP1 SNCA SPAG9 ZNF709
Entrez ID		163051	382
HPRD ID		08236	02714
Ensembl ID		ENSG00000242852	ENSG00000165527
Uniprot IDs		Q8N972	P62330
PDB IDs			1E0S 2A5D 2A5F 2A5G 2BAO 2BAU 2J5X 2W83 3LVQ 3LVR 3N5C 3PCR 4FME 4KAX 6BBP 6BBQ 6PAU 7RK3 7XRD
Enriched GO Terms of Interacting Partners?		Ruffle Assembly Positive Regulation Of Mitotic Cytokinesis Thioesterase Binding Response To Bacterial Lipoprotein Positive Regulation Of Keratinocyte Migration Maintenance Of Postsynaptic Specialization Structure Positive Regulation Of Mitotic Cytokinetic Process Negative Regulation Of Protein Localization To Cell Surface Cellular Response To Diacyl Bacterial Lipopeptide Negative Regulation Of Dendrite Development Regulation Of Mitotic Cytokinesis Protein Localization To Cleavage Furrow Positive Regulation Of Focal Adhesion Disassembly Erythrocyte Apoptotic Process Protein Localization To Endosome Cellular Response To Bacterial Lipopeptide Maintenance Of Postsynaptic Density Structure Myeloid Cell Apoptotic Process Hepatocyte Apoptotic Process Filopodium Membrane Postsynaptic Density Organization Postsynaptic Specialization Organization Regulation Of Presynapse Assembly Regulation Of Presynapse Organization Ruffle Organization Cortical Actin Cytoskeleton Organization Maintenance Of Synapse Structure Establishment Of Epithelial Cell Polarity Protein Localization To Cell Surface Negative Regulation Of Receptor-mediated Endocytosis Flemming Body Regulation Of Rac Protein Signal Transduction Regulation Of Protein Localization To Cell Surface Synaptic Vesicle Endocytosis Vesicle Docking Involved In Exocytosis Presynaptic Endocytosis Response To Nerve Growth Factor Cortical Cytoskeleton Organization Regulation Of Filopodium Assembly Positive Regulation Of Cytokinesis Cellular Response To Nerve Growth Factor Stimulus Epithelial Cell Apoptotic Process Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Epithelial Cell Migration Cell Junction Maintenance Regulation Of Dendritic Spine Development Cleavage Furrow Vesicle Docking Cellular Component Maintenance Mitotic Cytokinesis	Vesicle-mediated Transport Cytoplasmic Vesicle Intracellular Protein Localization Membrane Coat Establishment Of Localization In Cell Trans-Golgi Network Membrane Receptor-mediated Endocytosis Endocytosis Receptor Internalization Clathrin-coated Pit Protein Transport Melanosome Assembly Vesicle-mediated Transport In Synapse Regulation Of Vesicle-mediated Transport Cellular Localization Cytoplasmic Vesicle Membrane Organelle Localization Establishment Of Vesicle Localization Platelet Dense Granule Organization Import Into Cell Clathrin-coated Vesicle Cargo Loading, AP-3-mediated Golgi Membrane Establishment Of Protein Localization Vesicle Localization Clathrin-dependent Endocytosis Cellular Component Assembly Endocytic Vesicle Membrane Synaptic Vesicle Transport Melanosome Organization AP-3 Adaptor Complex Pigment Granule Organization Synaptic Vesicle Endocytosis Clathrin Adaptor Complex Positive Regulation Of Endocytosis GTPase Activator Activity Presynaptic Endocytosis Plasma Membrane Lysosomal Membrane Angiotensin Receptor Binding Golgi Apparatus Establishment Of Organelle Localization Secretion Post-Golgi Vesicle-mediated Transport Secretion By Cell Localization Within Membrane Intracellular Transport Regulation Of Cellular Component Organization Protein Localization To Plasma Membrane Anterograde Synaptic Vesicle Transport Focal Adhesion
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