SAXO1 and AKAP8L

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SAXO1	AKAP8L
Description		stabilizer of axonemal microtubules 1	A-kinase anchoring protein 8 like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Centriole Cytoskeleton Axonemal Microtubule Cilium Motile Cilium Ciliary Basal Body Sperm Flagellum Cell Projection	Chromatin Nucleus Nucleoplasm Cytoplasm Nuclear Matrix PML Body Nuclear Speck Ribonucleoprotein Complex
	Molecular Function	Protein Binding Microtubule Binding	DNA Binding RNA Binding Protein Binding Lamin Binding Zinc Ion Binding DEAD/H-box RNA Helicase Binding Protein Kinase A Regulatory Subunit Binding Histone Deacetylase Binding Metal Ion Binding
	Biological Process	Cold Acclimation Cell Projection Organization Positive Regulation Of Cilium Assembly Protein Stabilization Cellular Response To Cold	MRNA Processing Mitotic Chromosome Condensation RNA Splicing Regulation Of MRNA Export From Nucleus Cell Cycle G2/M Phase Transition Positive Regulation Of Transcription By RNA Polymerase II Nuclear Membrane Disassembly
Pathways			Formation of WDR5-containing histone-modifying complexes
Drugs
Diseases
GWAS		Cardiovascular event in colchicine-treated recent myocardial infarction (time to event) ( 33560138) Prudent dietary pattern ( 28644415)	Red blood cell count ( 32888494)
Interacting Genes		48 interacting genes: ACTMAP ACTN2 AKAP8L ARMC7 BAG4 BEGAIN CARD9 CDKN2D CFAP206 CHERP CPNE7 CRK CYSRT1 FAM124A FBXO17 FHL2 FHL3 FHL5 GLYCTK HEXIM2 HOMER3 HSF2BP IQUB KIR3DX1 KLHL40 LMO1 LMO2 MAPK9 MVP NEK6 NUDT22 OIP5 OSGIN1 PFDN5 PLEKHG4 PM20D2 POLR1C SMARCB1 SORBS3 STK16 TNK1 TRIB3 TRIP6 VPS28 WWOX ZMAT1 ZMYND12 ZMYND19	60 interacting genes: ABI2 ATOSB ATPAF2 CARHSP1 CATSPER1 CCDC120 CCDC24 CDC6 CNNM3 CREB5 CSTF2 CSTF2T DGCR6 DHX9 DMRT3 DSCR9 EMD ENKD1 FOXD4 GPANK1 GPS2 HEMK1 HGS HSF4 HUNK INCA1 KPRP LAGE3 LBR MYOZ1 MYPOP PATZ1 PCDHB14 PEF1 PITX1 PLEKHN1 PRKAA2 PRKACA PRPF40A PTP4A2 RAMAC RTP5 RUSC1 SAMD4A SAXO1 SAXO4 SH3RF2 SNRPC TEKT4 TEKT5 TENT5B TFAP2D TIAL1 TLE5 TMPO TMSB4X TRIB3 TSGA10IP WDR25 ZNF366
Entrez ID		158297	26993
HPRD ID		16676	10641
Ensembl ID		ENSG00000155875	ENSG00000011243
Uniprot IDs		B3KQ57 F6S232 Q5VZT6 Q8IYX7	Q9ULX6
PDB IDs
Enriched GO Terms of Interacting Partners?		Cytoplasm Transcription Coactivator Activity Regulation Of Calcineurin-mediated Signaling Regulation Of Calcineurin-NFAT Signaling Cascade	Protein Binding Sperm Flagellum
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