SAXO1 and OSGIN1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		SAXO1	OSGIN1
Description		stabilizer of axonemal microtubules 1	oxidative stress induced growth inhibitor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Centriole Cytoskeleton Axonemal Microtubule Cilium Motile Cilium Ciliary Basal Body Sperm Flagellum Cell Projection	Midbody
	Molecular Function	Protein Binding Microtubule Binding	Monooxygenase Activity Protein Binding Growth Factor Activity Oxidoreductase Activity
	Biological Process	Cold Acclimation Cell Projection Organization Positive Regulation Of Cilium Assembly Protein Stabilization Cellular Response To Cold	Signal Transduction Cell Differentiation Negative Regulation Of Cell Growth
Pathways
Drugs
Diseases
GWAS		Cardiovascular event in colchicine-treated recent myocardial infarction (time to event) ( 33560138) Prudent dietary pattern ( 28644415)	Alanine aminotransferase levels ( 33547301) LDL cholesterol ( 30275531) Liver enzyme levels (alanine transaminase) ( 33972514) Liver enzyme levels (alkaline phosphatase) ( 33972514) Pursuit maintenance gain ( 29064472) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872) Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		48 interacting genes: ACTMAP ACTN2 AKAP8L ARMC7 BAG4 BEGAIN CARD9 CDKN2D CFAP206 CHERP CPNE7 CRK CYSRT1 FAM124A FBXO17 FHL2 FHL3 FHL5 GLYCTK HEXIM2 HOMER3 HSF2BP IQUB KIR3DX1 KLHL40 LMO1 LMO2 MAPK9 MVP NEK6 NUDT22 OIP5 OSGIN1 PFDN5 PLEKHG4 PM20D2 POLR1C SMARCB1 SORBS3 STK16 TNK1 TRIB3 TRIP6 VPS28 WWOX ZMAT1 ZMYND12 ZMYND19	47 interacting genes: AKT1 ARNT2 ATM BCAR3 BEND7 BTBD2 CAPN3 CCDC33 CENPN CRX DECR2 DNAJA3 FGFR4 GCLM HOMEZ IKBKG IKZF3 INCA1 KATNBL1 KRAS KRT75 LNX1 MEI4 MEIS2 MEOX1 MEOX2 MTERF4 PAX5 PDE4A PDE4C PICK1 POLDIP3 POLR2G PPM1D PTEN REL SAXO1 SMARCB1 SORBS3 TCF12 TCF4 TLE5 TRIM54 XRCC3 ZBTB42 ZC2HC1C ZKSCAN4
Entrez ID		158297	29948
HPRD ID		16676	06412
Ensembl ID		ENSG00000155875	ENSG00000140961
Uniprot IDs		B3KQ57 F6S232 Q5VZT6 Q8IYX7	Q9UJX0
PDB IDs
Enriched GO Terms of Interacting Partners?		Cytoplasm Transcription Coactivator Activity Regulation Of Calcineurin-mediated Signaling Regulation Of Calcineurin-NFAT Signaling Cascade	Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Metabolic Process Regulation Of Gene Expression Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Macromolecule Biosynthetic Process Protein-containing Complex Binding Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Positive Regulation Of Biosynthetic Process Protein Binding DNA Binding Regulation Of Macromolecule Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Positive Regulation Of Macromolecule Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity Somite Specification Positive Regulation Of Metabolic Process Chromatin Regulation Of Metabolic Process Nervous System Development Activation-induced Cell Death Of T Cells Identical Protein Binding Regulation Of Intracellular Signal Transduction Regulation Of Signal Transduction Developmental Process Response To Nitrosative Stress Positive Regulation Of Proteolysis CAMP Catabolic Process Regulation Of Cell Communication Regulation Of Signaling System Development Regulation Of Cell Population Proliferation Anoikis HMG Box Domain Binding Nucleus Embryonic Pattern Specification Cyclic Nucleotide Catabolic Process Myelin Maintenance Nucleoplasm Positive Regulation Of Intracellular Signal Transduction Segment Specification
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