SAXO1 and TNK1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SAXO1	TNK1
Description		stabilizer of axonemal microtubules 1	tyrosine kinase non receptor 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Centriole Cytoskeleton Axonemal Microtubule Cilium Motile Cilium Ciliary Basal Body Sperm Flagellum Cell Projection	Cytoplasm Plasma Membrane Membrane
	Molecular Function	Protein Binding Microtubule Binding	Nucleotide Binding Protein Kinase Activity Protein Tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity
	Biological Process	Cold Acclimation Cell Projection Organization Positive Regulation Of Cilium Assembly Protein Stabilization Cellular Response To Cold	Protein Phosphorylation Protein Autophosphorylation
Pathways
Drugs			Fostamatinib
Diseases
GWAS		Cardiovascular event in colchicine-treated recent myocardial infarction (time to event) ( 33560138) Prudent dietary pattern ( 28644415)
Interacting Genes		48 interacting genes: ACTMAP ACTN2 AKAP8L ARMC7 BAG4 BEGAIN CARD9 CDKN2D CFAP206 CHERP CPNE7 CRK CYSRT1 FAM124A FBXO17 FHL2 FHL3 FHL5 GLYCTK HEXIM2 HOMER3 HSF2BP IQUB KIR3DX1 KLHL40 LMO1 LMO2 MAPK9 MVP NEK6 NUDT22 OIP5 OSGIN1 PFDN5 PLEKHG4 PM20D2 POLR1C SMARCB1 SORBS3 STK16 TNK1 TRIB3 TRIP6 VPS28 WWOX ZMAT1 ZMYND12 ZMYND19	8 interacting genes: FAM168A GRB10 PLCG1 SAXO1 SS18L1 UBC ZNF250 ZNF329
Entrez ID		158297	8711
HPRD ID		16676	09730
Ensembl ID		ENSG00000155875	ENSG00000174292
Uniprot IDs		B3KQ57 F6S232 Q5VZT6 Q8IYX7	Q13470
PDB IDs			7T8J 7TCY 7TDY 7U4W 7U4Z 9CPL
Enriched GO Terms of Interacting Partners?		Cytoplasm Transcription Coactivator Activity Regulation Of Calcineurin-mediated Signaling Regulation Of Calcineurin-NFAT Signaling Cascade
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