AMOT and C1orf216

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		AMOT	C1orf216
Gene Name		angiomotin	chromosome 1 open reading frame 216
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Stress Fiber Ruffle Cytoplasm Cytosol Actin Filament Tight Junction COP9 Signalosome External Side Of Plasma Membrane Cell Surface Integral Component Of Membrane Lamellipodium Endocytic Vesicle
	Molecular Function	Receptor Activity Protein Binding Angiostatin Binding
	Biological Process	Vasculogenesis In Utero Embryonic Development Gastrulation With Mouth Forming Second Establishment Of Cell Polarity Involved In Ameboidal Cell Migration Chemotaxis Cell-cell Junction Assembly Negative Regulation Of Angiogenesis Actin Cytoskeleton Organization Regulation Of Cell Migration Negative Regulation Of GTPase Activity Cellular Protein Localization Hippo Signaling Positive Regulation Of Embryonic Development Cell Migration Involved In Gastrulation Negative Regulation Of Vascular Permeability Blood Vessel Endothelial Cell Migration Positive Regulation Of Blood Vessel Endothelial Cell Migration Positive Regulation Of Cell Size Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Stress Fiber Assembly
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		21 interactors: ACTA1 APP C1orf216 KRT15 KRT31 LATS1 LATS2 LMO4 LURAP1 MAGEA4 MAGI1 MAPK3 MED4 NEDD4 PIN1 PLG PPP2R4 SEPT1 SNAPC5 UNC119 WDYHV1	28 interactors: AES AMOT CCDC114 CCDC136 CCDC158 CDR2 CEP170P1 GGA1 KRT13 KRT15 KRT31 KRT38 KRT40 LINC00521 MED4 MTUS2 MYRIP NMI NRBF2 NUP62 PSMC6 RALBP1 TPM1 TPM3 TRAF1 TRIM54 USHBP1 ZDHHC17
Entrez ID		154796	127703
HPRD ID		02327	08798
Ensembl ID		ENSG00000126016	ENSG00000142686
Uniprot IDs		Q4VCS5	Q8TAB5
PDB IDs
Enriched GO Terms of Interacting Partners?		Tissue Development Regulation Of Phosphorus Metabolic Process Regulation Of Cellular Amino Acid Metabolic Process Regulation Of Protein Phosphorylation Regulation Of Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Cellular Ketone Metabolic Process Regulation Of Phosphorylation Epidermis Development Cell Cycle Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Hippo Signaling Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Protein Kinase Activity Negative Regulation Of Phosphorylation Cell Division Regulation Of Kinase Activity Negative Regulation Of Cellular Protein Metabolic Process Regulation Of ERK1 And ERK2 Cascade Platelet Activation Intracellular Receptor Signaling Pathway Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Protein Metabolic Process Positive Regulation Of Protein Modification Process DNA-templated Transcription, Initiation Positive Regulation Of Metabolic Process Mitotic Spindle Organization In Nucleus Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Negative Regulation Of Clathrin-mediated Endocytosis Negative Regulation Of Apolipoprotein Binding Transmission Of Virus Development Involved In Symbiotic Interaction Neuromuscular Junction Development Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Cellular Metabolic Process Regulation Of Signal Transduction Regulation Of Protein Tyrosine Kinase Activity Neuron Death Regulation Of Sodium Ion Transport Epithelium Development Negative Regulation Of Signal Transduction Protein Peptidyl-prolyl Isomerization Platelet Degranulation Response To Abiotic Stimulus Intracellular Steroid Hormone Receptor Signaling Pathway Skeletal Muscle Fiber Adaptation Synaptic Growth At Neuromuscular Junction Negative Regulation Of Caveolin-mediated Endocytosis Organ Development	Actin-myosin Filament Sliding Muscle Filament Sliding Actin-mediated Cell Contraction Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Actin Filament Bundle Assembly Positive Regulation Of Heart Rate By Epinephrine Actin Filament-based Movement Regulation Of Stress Fiber Assembly Cellular Response To Stimulus Regulation Of Signaling Establishment Of Cell Polarity Involved In Ameboidal Cell Migration
Tagcloud ?		actin alanine amotl2 amots angiomotin collectively consensus contain core dissociation endogenously exogenous filaments hippo hxrxxs lats1 lats2 mapping mediate members mimic negatively phospho promoted s175a s175d serine taz yap
Tagcloud (Difference) ?		actin alanine amotl2 amots angiomotin collectively consensus contain core dissociation endogenously exogenous filaments hippo hxrxxs lats1 lats2 mapping mediate members mimic negatively phospho promoted s175a s175d serine taz yap
Tagcloud (Intersection) ?