C1orf216 and HAUS8

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		C1orf216	HAUS8
Description		chromosome 1 open reading frame 216	HAUS augmin like complex subunit 8
Image		No pdb structure
GO Annotations	Cellular Component		Spindle Pole Cytoplasm Centrosome Spindle Cytosol Cytoskeleton Microtubule Nuclear Microtubule HAUS Complex Mitotic Spindle Microtubule
	Molecular Function	Protein Binding	Protein Binding Microtubule Binding
	Biological Process		Centrosome Cycle Regulation Of Microtubule Nucleation Spindle Assembly Cell Division
Pathways			Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS			Mean corpuscular hemoglobin concentration ( 32888494) Mosquito bite size ( 28199695) Selective IgA deficiency ( 27723758) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		71 interacting genes: ABI2 AIMP2 AMOT BORCS6 CCDC136 CCDC158 CCDC197 CDR2 CDR2L CENPH CEP170P1 CEP55 CMC2 DES DMAP1 EIF3F EXOC5 FSD2 GGA1 HAP1 HAUS8 IFT20 KLHL20 KRT13 KRT15 KRT16 KRT24 KRT27 KRT31 KRT33B KRT34 KRT36 KRT38 KRT39 KRT40 KRT75 KRT76 LRRC61 MAGEA6 MDFI MED4 MIS18A MLPH MRFAP1L1 MTUS2 MYRIP NECAB2 NMI NRBF2 NUP62 ODAD1 PKNOX2 PPP1R16A PSMC6 RALBP1 SERTAD3 SNW1 SYCE1L THAP1 TLE5 TMCO5A TPM1 TPM3 TRAF1 TRIM54 TRIM72 USHBP1 VPS52 WASHC1 ZDHHC17 ZNF620	14 interacting genes: APP C1orf216 CCHCR1 DEUP1 HAUS6 HSPB1 NME7 NRDE2 NTAQ1 NUP54 OGT TXN2 USHBP1 ZG16B
Entrez ID		127703	93323
HPRD ID		08798	11318
Ensembl ID		ENSG00000142686	ENSG00000131351
Uniprot IDs		Q8TAB5	Q9BT25
PDB IDs			7SQK
Enriched GO Terms of Interacting Partners?		Intermediate Filament Organization Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Keratin Filament Intermediate Filament Supramolecular Fiber Organization Structural Molecule Activity Cytoskeleton Cytoskeleton Organization Epithelial Cell Differentiation Morphogenesis Of An Epithelium Tissue Morphogenesis Protein Binding Organelle Organization Anatomical Structure Morphogenesis Exocyst Intermediate Filament Cytoskeleton Structural Constituent Of Cytoskeleton Identical Protein Binding Cytosol Muscle Thin Filament Tropomyosin Myosin Binding Small GTPase Binding Epidermis Development Cell Differentiation Actin Filament Post-Golgi Vesicle-mediated Transport Actin Cytoskeleton	Amyloid-beta Complex Growth Cone Lamellipodium Cytoskeleton-dependent Intracellular Transport Regulation Of Response To Calcium Ion Regulation Of Glycolytic Process Microtubule-based Transport Transport Along Microtubule Amylin Binding Positive Regulation Of Toll Signaling Pathway Microtubule-based Process Negative Regulation Of Protein Kinase C Signaling Spindle Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Regulation Of Microtubule Nucleation Protein-N-terminal Glutamine Amidohydrolase Activity
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