C1orf216 and NUP62

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		C1orf216	NUP62
Gene Name		chromosome 1 open reading frame 216	nucleoporin 62kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Spindle Pole Nuclear Envelope Nuclear Pore Cytoplasm Ribonucleoprotein Complex Nucleocytoplasmic Shuttling Complex Nuclear Membrane Intracellular Membrane-bounded Organelle Pore Complex
	Molecular Function		Chromatin Binding Nucleocytoplasmic Transporter Activity Protein Binding Structural Constituent Of Nuclear Pore Receptor Signaling Complex Scaffold Activity SH2 Domain Binding Ubiquitin Binding Thyroid Hormone Receptor Binding PTB Domain Binding
	Biological Process		Mitotic Cell Cycle Carbohydrate Metabolic Process Transcription, DNA-templated Nucleocytoplasmic Transport Mitotic Nuclear Envelope Disassembly Cell Surface Receptor Signaling Pathway Cell Aging Cell Death Negative Regulation Of Cell Proliferation Hexose Transport Pathogenesis Hormone-mediated Signaling Pathway Regulation Of Signal Transduction Gene Expression Regulation Of Glucose Transport Protein Transport Glucose Transport Viral Process Viral Life Cycle Viral Transcription Cytokine-mediated Signaling Pathway Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of MAP Kinase Activity Small Molecule Metabolic Process Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Transcription, DNA-templated Regulation Of Ras Protein Signal Transduction Negative Regulation Of Ras Protein Signal Transduction MRNA Transport Transmembrane Transport
Pathways			Mitotic Prophase HIV Infection Nuclear import of Rev protein Regulatory RNA pathways Rev-mediated nuclear export of HIV RNA Nuclear Envelope Breakdown SLC-mediated transmembrane transport M Phase Influenza Life Cycle HIV Life Cycle Influenza Viral RNA Transcription and Replication Rev-mediated nuclear export of HIV RNA Myoclonic epilepsy of Lafora Glycogen storage diseases Transcriptional regulation by small RNAs Vpr-mediated nuclear import of PICs ISG15 antiviral mechanism Interferon Signaling Host Interactions of HIV factors Nuclear Pore Complex (NPC) Disassembly Regulation of Glucokinase by Glucokinase Regulatory Protein Cytokine Signaling in Immune system Interactions of Vpr with host cellular proteins Interactions of Rev with host cellular proteins Influenza Infection Hexose transport Cell Cycle, Mitotic Late Phase of HIV Life Cycle Antiviral mechanism by IFN-stimulated genes Viral Messenger RNA Synthesis Metabolism of carbohydrates Glucose transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		28 interactors: AES AMOT CCDC114 CCDC136 CCDC158 CDR2 CEP170P1 GGA1 KRT13 KRT15 KRT31 KRT38 KRT40 LINC00521 MED4 MTUS2 MYRIP NMI NRBF2 NUP62 PSMC6 RALBP1 TPM1 TPM3 TRAF1 TRIM54 USHBP1 ZDHHC17	65 interactors: ABI2 ADAM15 AGR3 ATXN7 BFSP1 BLOC1S6 C1orf216 CCDC121 CCDC146 CCDC150 CCDC153 CCDC53 CCHCR1 CENPU CEP57L1 CLIC1 CRCT1 DDX3X DGCR6 DTNB FABP3 GOPC GORASP2 GTF2E2 HAUS1 HSF2 IFT20 IK IKBIP IPO5 ISCU KANSL1 KIFC3 KLHL32 KPNA1 KPNA2 KPNB1 KRT20 LMO2 MUC1 MYO15B NFX1 NUP153 NUP54 NUP98 NUPL1 NUTF2 NXF1 NXF2 OGT OIP5 PBX2 PHF21A PIN1 PTMA RANBP2 SMARCE1 SNAPC5 SP1 SSC5D THAP1 TRAF3 TXLNA XPO1 XPO6
Entrez ID		127703	23636
HPRD ID		08798	05782
Ensembl ID		ENSG00000142686	ENSG00000213024
Uniprot IDs		Q8TAB5	P37198
PDB IDs			2H4D
Enriched GO Terms of Interacting Partners?		Actin-myosin Filament Sliding Muscle Filament Sliding Actin-mediated Cell Contraction Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Actin Filament Bundle Assembly Positive Regulation Of Heart Rate By Epinephrine Actin Filament-based Movement Regulation Of Stress Fiber Assembly Cellular Response To Stimulus Regulation Of Signaling Establishment Of Cell Polarity Involved In Ameboidal Cell Migration	Nucleocytoplasmic Transport Nuclear Transport Viral Process Cytoplasmic Transport MRNA Transport RNA Transport RNA Localization Intracellular Transport Nuclear Import Nucleus Organization Viral Life Cycle NLS-bearing Protein Import Into Nucleus Mitotic Nuclear Envelope Disassembly Nuclear Envelope Disassembly Establishment Of Localization In Cell Protein Transport Protein Localization To Nucleus Cytokine-mediated Signaling Pathway Establishment Of Protein Localization Nuclear Export Cellular Localization Protein Import Into Nucleus Protein Export From Nucleus Intracellular Transport Of Virus Nuclear Envelope Organization Glucose Transport Protein Localization Cellular Response To Cytokine Stimulus Organelle Organization Protein Import Mitotic Cell Cycle Hexose Transport Cellular Protein Localization Viral Transcription Regulation Of Glucose Transport Response To Cytokine RNA Biosynthetic Process Intracellular Protein Transport Cell Cycle Carbohydrate Transport Regulation Of Gluconeogenesis Involved In Cellular Glucose Homeostasis Cellular Response To Organic Substance Protein Localization To Organelle Gene Expression Response To Organic Substance Protein Targeting Nuclear Pore Complex Assembly Pathogenesis Establishment Of Protein Localization To Organelle Ribosomal Protein Import Into Nucleus
Tagcloud ?			barr bblf2 bblf4 betaherpesviruses bglf4 bslf1 cotransfected dilation ebv egress epstein fg gammaherpesviruses gateways import importin lytic mpm nls nlss nucleocapsids nucleocytoplasmic nucleoporins nup153 nups pore reorganization replicating vca
Tagcloud (Difference) ?			barr bblf2 bblf4 betaherpesviruses bglf4 bslf1 cotransfected dilation ebv egress epstein fg gammaherpesviruses gateways import importin lytic mpm nls nlss nucleocapsids nucleocytoplasmic nucleoporins nup153 nups pore reorganization replicating vca
Tagcloud (Intersection) ?