C1orf216 and CMC2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		C1orf216	CMC2
Description		chromosome 1 open reading frame 216	C-X9-C motif containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Mitochondrion Cytosol
	Molecular Function	Protein Binding	Protein Binding
	Biological Process
Pathways			Mitochondrial protein import
Drugs
Diseases
GWAS			Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		71 interacting genes: ABI2 AIMP2 AMOT BORCS6 CCDC136 CCDC158 CCDC197 CDR2 CDR2L CENPH CEP170P1 CEP55 CMC2 DES DMAP1 EIF3F EXOC5 FSD2 GGA1 HAP1 HAUS8 IFT20 KLHL20 KRT13 KRT15 KRT16 KRT24 KRT27 KRT31 KRT33B KRT34 KRT36 KRT38 KRT39 KRT40 KRT75 KRT76 LRRC61 MAGEA6 MDFI MED4 MIS18A MLPH MRFAP1L1 MTUS2 MYRIP NECAB2 NMI NRBF2 NUP62 ODAD1 PKNOX2 PPP1R16A PSMC6 RALBP1 SERTAD3 SNW1 SYCE1L THAP1 TLE5 TMCO5A TPM1 TPM3 TRAF1 TRIM54 TRIM72 USHBP1 VPS52 WASHC1 ZDHHC17 ZNF620	2 interacting genes: C1orf216 CTNNA3
Entrez ID		127703	56942
HPRD ID		08798	16783
Ensembl ID		ENSG00000142686	ENSG00000103121
Uniprot IDs		Q8TAB5	Q9NRP2
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Organization Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Keratin Filament Intermediate Filament Supramolecular Fiber Organization Structural Molecule Activity Cytoskeleton Cytoskeleton Organization Epithelial Cell Differentiation Morphogenesis Of An Epithelium Tissue Morphogenesis Protein Binding Organelle Organization Anatomical Structure Morphogenesis Exocyst Intermediate Filament Cytoskeleton Structural Constituent Of Cytoskeleton Identical Protein Binding Cytosol Muscle Thin Filament Tropomyosin Myosin Binding Small GTPase Binding Epidermis Development Cell Differentiation Actin Filament Post-Golgi Vesicle-mediated Transport Actin Cytoskeleton	Cardiac Muscle Cell-cardiac Muscle Cell Adhesion Bundle Of His Cell-Purkinje Myocyte Adhesion Involved In Cell Communication Fascia Adherens Regulation Of Ventricular Cardiac Muscle Cell Action Potential Regulation Of Heart Rate By Cardiac Conduction Regulation Of Cardiac Muscle Cell Action Potential Regulation Of Cardiac Muscle Cell Contraction Heterotypic Cell-cell Adhesion Desmosome Cardiac Conduction Regulation Of Action Potential Homotypic Cell-cell Adhesion Regulation Of Cardiac Muscle Contraction Beta-catenin Binding Regulation Of Heart Rate Regulation Of Striated Muscle Contraction Regulation Of Heart Contraction Regulation Of Muscle Contraction Actin Filament Binding Lamellipodium Adherens Junction
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