C1orf216 and TMCO5A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		C1orf216	TMCO5A
Description		chromosome 1 open reading frame 216	transmembrane and coiled-coil domains 5A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Nuclear Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process
Pathways
Drugs
Diseases
GWAS			Body size at age 10 ( 32376654) Femoral neck bone mineral density ( 29499414) Gut microbiota (bacterial taxa) ( 27723756) Lumbar spine bone mineral density ( 29499414) Major depressive disorder ( 27479909) NASH resolution in nonalcoholic steatohepatitis ( 31832568) Total body bone mineral density ( 29304378) Urate levels in overweight individuals ( 25811787)
Interacting Genes		71 interacting genes: ABI2 AIMP2 AMOT BORCS6 CCDC136 CCDC158 CCDC197 CDR2 CDR2L CENPH CEP170P1 CEP55 CMC2 DES DMAP1 EIF3F EXOC5 FSD2 GGA1 HAP1 HAUS8 IFT20 KLHL20 KRT13 KRT15 KRT16 KRT24 KRT27 KRT31 KRT33B KRT34 KRT36 KRT38 KRT39 KRT40 KRT75 KRT76 LRRC61 MAGEA6 MDFI MED4 MIS18A MLPH MRFAP1L1 MTUS2 MYRIP NECAB2 NMI NRBF2 NUP62 ODAD1 PKNOX2 PPP1R16A PSMC6 RALBP1 SERTAD3 SNW1 SYCE1L THAP1 TLE5 TMCO5A TPM1 TPM3 TRAF1 TRIM54 TRIM72 USHBP1 VPS52 WASHC1 ZDHHC17 ZNF620	7 interacting genes: BET1 C1orf216 GOSR2 PRH1 TMEM60 TSPAN18 VAMP5
Entrez ID		127703	145942
HPRD ID		08798	11341
Ensembl ID		ENSG00000142686	ENSG00000166069
Uniprot IDs		Q8TAB5	A0A024R9I9 Q8N6Q1
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Organization Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Keratin Filament Intermediate Filament Supramolecular Fiber Organization Structural Molecule Activity Cytoskeleton Cytoskeleton Organization Epithelial Cell Differentiation Morphogenesis Of An Epithelium Tissue Morphogenesis Protein Binding Organelle Organization Anatomical Structure Morphogenesis Exocyst Intermediate Filament Cytoskeleton Structural Constituent Of Cytoskeleton Identical Protein Binding Cytosol Muscle Thin Filament Tropomyosin Myosin Binding Small GTPase Binding Epidermis Development Cell Differentiation Actin Filament Post-Golgi Vesicle-mediated Transport Actin Cytoskeleton	SNARE Complex SNAP Receptor Activity Golgi Vesicle Transport Vesicle Fusion Organelle Membrane Fusion Vesicle-mediated Transport Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Organelle Fusion Membrane Fusion Vesicle Fusion With Golgi Apparatus Endomembrane System
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