MED14 and MED29

Number of citations of the paper that reports this interaction (PMID 14576168)
11

Data Source:
HPRD (in vitro)

		MED14	MED29
Gene Name		mediator complex subunit 14	mediator complex subunit 29
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Membrane Mediator Complex	Nucleoplasm Mediator Complex
	Molecular Function	RNA Polymerase II Transcription Cofactor Activity Transcription Cofactor Activity Transcription Coactivator Activity Receptor Activity Protein Binding Ligand-dependent Nuclear Receptor Transcription Coactivator Activity Vitamin D Receptor Binding Thyroid Hormone Receptor Binding	Protein Binding
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Gene Expression Stem Cell Maintenance Intracellular Steroid Hormone Receptor Signaling Pathway Androgen Receptor Signaling Pathway Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter	Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways		PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)	PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-Protein Interactions		20 interactors: ACTN1 ACTN2 AR CTDP1 DCTN1 ESR1 ESR2 HNF4A MED1 MED29 MED9 MYC NECAB2 NR3C1 PARP1 PPARGC1A SREBF1 STAT2 UACA VDR	9 interactors: MED1 MED12 MED13 MED14 MED17 MED20 MED21 MED9 USP47
Entrez ID		9282	55588
HPRD ID		02172	13748
Ensembl ID		ENSG00000180182	ENSG00000063322
Uniprot IDs		O60244	B4DUA7 Q9NX70
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Transcription From RNA Polymerase II Promoter Intracellular Receptor Signaling Pathway Transcription, DNA-templated RNA Biosynthetic Process Cellular Response To Hormone Stimulus Hormone-mediated Signaling Pathway Regulation Of Nitrogen Compound Metabolic Process Cellular Response To Lipid Intracellular Steroid Hormone Receptor Signaling Pathway Cellular Response To Steroid Hormone Stimulus Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Organic Substance Steroid Hormone Mediated Signaling Pathway RNA Metabolic Process Regulation Of Metabolic Process Response To Hormone Gene Expression Regulation Of Nucleic Acid-templated Transcription Cellular Macromolecule Biosynthetic Process Response To Steroid Hormone Positive Regulation Of Transcription From RNA Polymerase II Promoter Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Response To Organic Substance Mammary Gland Branching Involved In Pregnancy Positive Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Response To Lipid Positive Regulation Of Cellular Biosynthetic Process Response To Organic Cyclic Compound Cellular Response To Organic Cyclic Compound Positive Regulation Of Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process Regulation Of Signaling Regulation Of Apoptotic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Cell Death Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process Gland Morphogenesis Positive Regulation Of Metabolic Process Mammary Gland Duct Morphogenesis Regulation Of Signal Transduction Regulation Of Transcription, DNA-templated	Androgen Receptor Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Intracellular Steroid Hormone Receptor Signaling Pathway DNA-templated Transcription, Initiation Transcription From RNA Polymerase II Promoter Intracellular Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Stem Cell Maintenance Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Stem Cell Development Gene Expression Nitrogen Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Cell Differentiation Stem Cell Differentiation Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Biosynthetic Process Regulation Of Metabolic Process Axis Elongation Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Differentiation Cell Development Base-excision Repair Thyroid Hormone Mediated Signaling Pathway Positive Regulation Of Metabolic Process Cellular Metabolic Process Developmental Growth Involved In Morphogenesis Enucleate Erythrocyte Development Positive Regulation Of Interferon-gamma-mediated Signaling Pathway Positive Regulation Of G0 To G1 Transition Axis Elongation Involved In Somitogenesis Depyrimidination Regulation Of Organ Morphogenesis
Tagcloud ?		bridges cha1 eliminated eukaryotes gal11 kin28 machinery med15 med17 med18 mediator module modules paf1 rbp1 recruitment remodeling rgr1 ser2 ser5 severely snf srb4 srb5 swi tata tbp ts unaffected
Tagcloud (Difference) ?		bridges cha1 eliminated eukaryotes gal11 kin28 machinery med15 med17 med18 mediator module modules paf1 rbp1 recruitment remodeling rgr1 ser2 ser5 severely snf srb4 srb5 swi tata tbp ts unaffected
Tagcloud (Intersection) ?