CRYAB and ACOT7

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CRYAB	ACOT7
Gene Name		crystallin, alpha B	acyl-CoA thioesterase 7
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Golgi Apparatus Cytosol Plasma Membrane Cell Surface Microtubule Cytoskeleton Z Disc Actin Filament Bundle Extracellular Vesicular Exosome	Nucleoplasm Cytoplasm Mitochondrion Cytosol Neuron Projection Cell Body Extracellular Vesicular Exosome
	Molecular Function	Structural Constituent Of Eye Lens Protein Binding Microtubule Binding Identical Protein Binding Protein Homodimerization Activity Metal Ion Binding Unfolded Protein Binding	Fatty-acyl-CoA Binding Protein Binding Palmitoyl-CoA Hydrolase Activity Long-chain Fatty Acyl-CoA Binding Protein Homodimerization Activity Carboxylic Ester Hydrolase Activity
	Biological Process	Response To Hypoxia Lens Development In Camera-type Eye Protein Folding Muscle Contraction Tubulin Complex Assembly Muscle Organ Development Aging Regulation Of Cell Death Negative Regulation Of Cell Growth Microtubule Polymerization Or Depolymerization Response To Estradiol Negative Regulation Of Intracellular Transport Response To Hydrogen Peroxide Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Protein Homooligomerization Stress-activated MAPK Cascade Apoptotic Process Involved In Morphogenesis Cellular Response To Gamma Radiation Negative Regulation Of Reactive Oxygen Species Metabolic Process	Fatty Acid Catabolic Process Coenzyme A Biosynthetic Process Medium-chain Fatty-acyl-CoA Catabolic Process Long-chain Fatty-acyl-CoA Catabolic Process Medium-chain Fatty Acid Biosynthetic Process Palmitic Acid Biosynthetic Process
Pathways
Drugs
Diseases
GWAS			QT interval ( 19305408)
Protein-Protein Interactions		44 interactors: ACOT7 APOC2 APP AVP B2M BAG3 BCL2L1 BMPR2 CASP3 CCL22 CCND1 CRYAA CRYBA1 CRYBB2 CRYGC CRYGD CS DDX20 DES EPB41 FCGR2A FGF2 GFAP HBA1 HSPB1 HSPB2 HSPB8 INS KRTAP19-5 KRTAP8-1 LALBA MDH2 MIP MRPL11 NGF PRKAG3 PSMA3 SNCA SOD1 TNPO2 TRAPPC6A TTN UBE2D1 VEGFA	10 interactors: ATXN1 ATXN1L CAMK2B CRYAB MAGEA6 POT1 TERF1 THAP1 TINF2 UBQLN1
Entrez ID		1410	11332
HPRD ID		00428	12517
Ensembl ID		ENSG00000109846	ENSG00000097021
Uniprot IDs		P02511	F5GWE2 O00154
PDB IDs		2KLR 2WJ7 2Y1Y 2Y1Z 2Y22 2YGD 3L1G 3SGM 3SGN 3SGO 3SGP 3SGR 3SGS	2QQ2
Enriched GO Terms of Interacting Partners?		Response To Stress Negative Regulation Of Cell Death Positive Regulation Of Protein Metabolic Process Regulation Of Protein Phosphorylation Regulation Of Cell Death Response To External Stimulus Negative Regulation Of Apoptotic Process Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Programmed Cell Death Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Regulation Of Phosphorus Metabolic Process Regulation Of Phosphorylation Response To Abiotic Stimulus Positive Regulation Of Protein Modification Process Positive Regulation Of Endothelial Cell Chemotaxis Positive Regulation Of Transferase Activity Regulation Of Cellular Protein Metabolic Process Visual Perception Sensory Perception Of Light Stimulus Regulation Of Apoptotic Process Negative Regulation Of Catalytic Activity Regulation Of Lipid Metabolic Process Response To Stimulus Regulation Of Catalytic Activity Positive Regulation Of Catalytic Activity Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Cellular Response To Oxidative Stress Regulation Of Proteolysis Regulation Of Protein Metabolic Process Positive Regulation Of Cell Growth Positive Regulation Of Growth Response To Wounding Neuron Apoptotic Process Camera-type Eye Development Positive Regulation Of Protein Autophosphorylation Positive Regulation Of Endothelial Cell Migration Positive Regulation Of Protein Phosphorylation Regulation Of Neuron Apoptotic Process Regulation Of Lipid Biosynthetic Process Organ Development Neuron Death Apoptotic Process Positive Regulation Of Blood Vessel Endothelial Cell Migration Eye Development Programmed Cell Death Sensory Organ Development Response To Oxidative Stress Platelet Degranulation Sensory Perception	Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Replication Telomere Maintenance Telomere Assembly Negative Regulation Of Chromosome Organization Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Negative Regulation Of DNA Metabolic Process Positive Regulation Of Telomere Maintenance Positive Regulation Of Organelle Organization Regulation Of Telomerase Activity Regulation Of DNA Replication RNA-dependent DNA Replication Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Chromosome Organization Negative Regulation Of Biosynthetic Process Regulation Of DNA Biosynthetic Process Lung Alveolus Development Regulation Of Organelle Organization Negative Regulation Of Protein ADP-ribosylation Positive Regulation Of DNA Strand Elongation Inhibitory G-protein Coupled Receptor Phosphorylation Regulation Of Cellular Component Organization Response To Abiotic Stimulus Regulation Of Protein ADP-ribosylation Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Activation Of Meiosis Involved In Egg Activation Telomeric Loop Formation Age-dependent Telomere Shortening Positive Regulation Of Hematopoietic Stem Cell Proliferation Telomere Formation Via Telomerase Positive Regulation Of Cell Division Telomere Maintenance Via Telomere Shortening Negative Regulation Of Protein Glycosylation Activation Of Meiosis Positive Regulation Of DNA Metabolic Process Regulation Of Apoptotic Process Regulation Of Metabolic Process Telomere Capping Protein Localization To Chromosome, Telomeric Region Positive Regulation Of Helicase Activity Regulation Of Cell Death Positive Regulation Of Telomerase Activity Regulation Of Hematopoietic Stem Cell Proliferation Positive Regulation Of Telomere Maintenance Via Telomerase
Tagcloud ?		adaptive aggregated antiapoptotic assisting cardiomyocyte cardiomyocytes chaperons confers correct crystallin elicit emphasizing folding hsp hsps interplay lumen mini misfolded mitigate myocardium myocytes referred stressed stresses undergo unfolded upr worldwide	16p11 17q21 2p21 autism auts2 cask categorised cnvs crebbp ctnnd2 delineating exonic grm8 homozygous incidental instrumental iq kb med13l microdeletion morbid ndds neurodevelopmental nrxn3 omim pafah1b1 satb2 sizing undiagnosed
Tagcloud (Difference) ?		adaptive aggregated antiapoptotic assisting cardiomyocyte cardiomyocytes chaperons confers correct crystallin elicit emphasizing folding hsp hsps interplay lumen mini misfolded mitigate myocardium myocytes referred stressed stresses undergo unfolded upr worldwide	16p11 17q21 2p21 autism auts2 cask categorised cnvs crebbp ctnnd2 delineating exonic grm8 homozygous incidental instrumental iq kb med13l microdeletion morbid ndds neurodevelopmental nrxn3 omim pafah1b1 satb2 sizing undiagnosed
Tagcloud (Intersection) ?