CRYAB and KRTAP8-1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CRYAB	KRTAP8-1
Gene Name		crystallin, alpha B	keratin associated protein 8-1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Golgi Apparatus Cytosol Plasma Membrane Cell Surface Microtubule Cytoskeleton Z Disc Actin Filament Bundle Extracellular Vesicular Exosome	Intermediate Filament
	Molecular Function	Structural Constituent Of Eye Lens Protein Binding Microtubule Binding Identical Protein Binding Protein Homodimerization Activity Metal Ion Binding Unfolded Protein Binding
	Biological Process	Response To Hypoxia Lens Development In Camera-type Eye Protein Folding Muscle Contraction Tubulin Complex Assembly Muscle Organ Development Aging Regulation Of Cell Death Negative Regulation Of Cell Growth Microtubule Polymerization Or Depolymerization Response To Estradiol Negative Regulation Of Intracellular Transport Response To Hydrogen Peroxide Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Protein Homooligomerization Stress-activated MAPK Cascade Apoptotic Process Involved In Morphogenesis Cellular Response To Gamma Radiation Negative Regulation Of Reactive Oxygen Species Metabolic Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		44 interactors: ACOT7 APOC2 APP AVP B2M BAG3 BCL2L1 BMPR2 CASP3 CCL22 CCND1 CRYAA CRYBA1 CRYBB2 CRYGC CRYGD CS DDX20 DES EPB41 FCGR2A FGF2 GFAP HBA1 HSPB1 HSPB2 HSPB8 INS KRTAP19-5 KRTAP8-1 LALBA MDH2 MIP MRPL11 NGF PRKAG3 PSMA3 SNCA SOD1 TNPO2 TRAPPC6A TTN UBE2D1 VEGFA	5 interactors: CRYAB DAB1 DAZAP2 PSMA3 RBPMS
Entrez ID		1410	337879
HPRD ID		00428	11221
Ensembl ID		ENSG00000109846	ENSG00000183640
Uniprot IDs		P02511	Q8IUC2
PDB IDs		2KLR 2WJ7 2Y1Y 2Y1Z 2Y22 2YGD 3L1G 3SGM 3SGN 3SGO 3SGP 3SGR 3SGS
Enriched GO Terms of Interacting Partners?		Response To Stress Negative Regulation Of Cell Death Positive Regulation Of Protein Metabolic Process Regulation Of Protein Phosphorylation Regulation Of Cell Death Response To External Stimulus Negative Regulation Of Apoptotic Process Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Programmed Cell Death Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Regulation Of Phosphorus Metabolic Process Regulation Of Phosphorylation Response To Abiotic Stimulus Positive Regulation Of Protein Modification Process Positive Regulation Of Endothelial Cell Chemotaxis Positive Regulation Of Transferase Activity Regulation Of Cellular Protein Metabolic Process Visual Perception Sensory Perception Of Light Stimulus Regulation Of Apoptotic Process Negative Regulation Of Catalytic Activity Regulation Of Lipid Metabolic Process Response To Stimulus Regulation Of Catalytic Activity Positive Regulation Of Catalytic Activity Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Cellular Response To Oxidative Stress Regulation Of Proteolysis Regulation Of Protein Metabolic Process Positive Regulation Of Cell Growth Positive Regulation Of Growth Response To Wounding Neuron Apoptotic Process Camera-type Eye Development Positive Regulation Of Protein Autophosphorylation Positive Regulation Of Endothelial Cell Migration Positive Regulation Of Protein Phosphorylation Regulation Of Neuron Apoptotic Process Regulation Of Lipid Biosynthetic Process Organ Development Neuron Death Apoptotic Process Positive Regulation Of Blood Vessel Endothelial Cell Migration Eye Development Programmed Cell Death Sensory Organ Development Response To Oxidative Stress Platelet Degranulation Sensory Perception	Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration Positive Regulation Of Protein Modification Process Cerebellum Structural Organization Positive Regulation Of Cellular Protein Metabolic Process Lateral Motor Column Neuron Migration Positive Regulation Of Protein Metabolic Process Spinal Cord Motor Neuron Migration Radial Glia Guided Migration Of Purkinje Cell Tubulin Complex Assembly Intracellular Signal Transduction Regulation Of Intracellular Transport Positive Regulation Of SMAD Protein Import Into Nucleus Golgi Localization Negative Regulation Of Astrocyte Differentiation Regulation Of SMAD Protein Import Into Nucleus Apoptotic Process Involved In Morphogenesis Positive Regulation Of Transferase Activity Cellular Response To Gamma Radiation Midgut Development Anatomical Structure Arrangement Negative Regulation Of JAK-STAT Cascade Regulation Of Catalytic Activity Cell Migration In Hindbrain Apoptotic Process Involved In Development Regulation Of Proteolysis Positive Regulation Of Cellular Metabolic Process Regulation Of Astrocyte Differentiation Positive Regulation Of Protein Phosphorylation Regulation Of Signal Transduction Developmental Programmed Cell Death Negative Regulation Of Glial Cell Differentiation Microtubule Polymerization Or Depolymerization Negative Regulation Of Catalytic Activity Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Reactive Oxygen Species Metabolic Process Positive Regulation Of Phosphorylation Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Negative Regulation Of Protein Metabolic Process Regulation Of Signaling Adult Walking Behavior Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Cerebellum Morphogenesis Response To Gamma Radiation Regulation Of Pathway-restricted SMAD Protein Phosphorylation Hindbrain Morphogenesis Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Apoptotic Process
Tagcloud ?		adaptive aggregated antiapoptotic assisting cardiomyocyte cardiomyocytes chaperons confers correct crystallin elicit emphasizing folding hsp hsps interplay lumen mini misfolded mitigate myocardium myocytes referred stressed stresses undergo unfolded upr worldwide
Tagcloud (Difference) ?		adaptive aggregated antiapoptotic assisting cardiomyocyte cardiomyocytes chaperons confers correct crystallin elicit emphasizing folding hsp hsps interplay lumen mini misfolded mitigate myocardium myocytes referred stressed stresses undergo unfolded upr worldwide
Tagcloud (Intersection) ?