CRYAB and LALBA

Number of citations of the paper that reports this interaction (PMID 21152271)
2

Data Source:
BioGRID (pull down)

		CRYAB	LALBA
Gene Name		crystallin, alpha B	lactalbumin, alpha-
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Golgi Apparatus Cytosol Plasma Membrane Cell Surface Microtubule Cytoskeleton Z Disc Actin Filament Bundle Extracellular Vesicular Exosome	Extracellular Space
	Molecular Function	Structural Constituent Of Eye Lens Protein Binding Microtubule Binding Identical Protein Binding Protein Homodimerization Activity Metal Ion Binding Unfolded Protein Binding	Lactose Synthase Activity Calcium Ion Binding
	Biological Process	Response To Hypoxia Lens Development In Camera-type Eye Protein Folding Muscle Contraction Tubulin Complex Assembly Muscle Organ Development Aging Regulation Of Cell Death Negative Regulation Of Cell Growth Microtubule Polymerization Or Depolymerization Response To Estradiol Negative Regulation Of Intracellular Transport Response To Hydrogen Peroxide Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Protein Homooligomerization Stress-activated MAPK Cascade Apoptotic Process Involved In Morphogenesis Cellular Response To Gamma Radiation Negative Regulation Of Reactive Oxygen Species Metabolic Process	Lactose Biosynthetic Process Apoptotic Process Signal Transduction Cell-cell Signaling Defense Response To Bacterium
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		44 interactors: ACOT7 APOC2 APP AVP B2M BAG3 BCL2L1 BMPR2 CASP3 CCL22 CCND1 CRYAA CRYBA1 CRYBB2 CRYGC CRYGD CS DDX20 DES EPB41 FCGR2A FGF2 GFAP HBA1 HSPB1 HSPB2 HSPB8 INS KRTAP19-5 KRTAP8-1 LALBA MDH2 MIP MRPL11 NGF PRKAG3 PSMA3 SNCA SOD1 TNPO2 TRAPPC6A TTN UBE2D1 VEGFA	7 interactors: B4GALT1 CRYAA CRYAB HIST2H2BE HIST2H3A HSPA8 UBC
Entrez ID		1410	3906
HPRD ID		00428	01024
Ensembl ID		ENSG00000109846	ENSG00000167531
Uniprot IDs		P02511	P00709
PDB IDs		2KLR 2WJ7 2Y1Y 2Y1Z 2Y22 2YGD 3L1G 3SGM 3SGN 3SGO 3SGP 3SGR 3SGS	1A4V 1B9O 1CB3 1HML 3B0I 3B0O 4L41
Enriched GO Terms of Interacting Partners?		Response To Stress Negative Regulation Of Cell Death Positive Regulation Of Protein Metabolic Process Regulation Of Protein Phosphorylation Regulation Of Cell Death Response To External Stimulus Negative Regulation Of Apoptotic Process Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Programmed Cell Death Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Regulation Of Phosphorus Metabolic Process Regulation Of Phosphorylation Response To Abiotic Stimulus Positive Regulation Of Protein Modification Process Positive Regulation Of Endothelial Cell Chemotaxis Positive Regulation Of Transferase Activity Regulation Of Cellular Protein Metabolic Process Visual Perception Sensory Perception Of Light Stimulus Regulation Of Apoptotic Process Negative Regulation Of Catalytic Activity Regulation Of Lipid Metabolic Process Response To Stimulus Regulation Of Catalytic Activity Positive Regulation Of Catalytic Activity Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Cellular Response To Oxidative Stress Regulation Of Proteolysis Regulation Of Protein Metabolic Process Positive Regulation Of Cell Growth Positive Regulation Of Growth Response To Wounding Neuron Apoptotic Process Camera-type Eye Development Positive Regulation Of Protein Autophosphorylation Positive Regulation Of Endothelial Cell Migration Positive Regulation Of Protein Phosphorylation Regulation Of Neuron Apoptotic Process Regulation Of Lipid Biosynthetic Process Organ Development Neuron Death Apoptotic Process Positive Regulation Of Blood Vessel Endothelial Cell Migration Eye Development Programmed Cell Death Sensory Organ Development Response To Oxidative Stress Platelet Degranulation Sensory Perception	Response To Stress Negative Regulation Of Fibril Organization Regulation Of Apoptotic Process Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Negative Regulation Of Intracellular Transport Regulation Of Cell Death Response To Stimulus Notch Signaling Pathway Regulation Of Fibril Organization Lactose Biosynthetic Process Carbohydrate Biosynthetic Process Clathrin Coat Disassembly Pathogenesis Hexose Metabolic Process Disaccharide Metabolic Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Apoptotic Process MAPK Cascade Negative Regulation Of Programmed Cell Death Cellular Carbohydrate Metabolic Process Negative Regulation Of Cell Death Tubulin Complex Assembly Penetration Of Zona Pellucida Positive Regulation Of Epithelial Cell Proliferation Involved In Wound Healing Monosaccharide Metabolic Process Protein Homooligomerization Positive Regulation Of Apoptotic Process Involved In Mammary Gland Involution Protein Complex Assembly Regulation Of Cellular Localization Signal Transduction By Phosphorylation Protein Folding Response To Abiotic Stimulus Negative Regulation Of Transcription, DNA-templated Response To Hypoxia Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Acrosome Reaction Viral Protein Processing Negative Regulation Of RNA Biosynthetic Process DNA Methylation On Cytosine Development Of Secondary Sexual Characteristics Chromatin Silencing At RDNA Negative Regulation Of Gene Expression Innate Immune Response In Mucosa Defense Response Negative Regulation Of Biosynthetic Process Oligosaccharide Biosynthetic Process Negative Regulation Of Transport Chaperone Mediated Protein Folding Requiring Cofactor Apoptotic Process Involved In Morphogenesis
Tagcloud ?		adaptive aggregated antiapoptotic assisting cardiomyocyte cardiomyocytes chaperons confers correct crystallin elicit emphasizing folding hsp hsps interplay lumen mini misfolded mitigate myocardium myocytes referred stressed stresses undergo unfolded upr worldwide	casein concentration csn1s1 csn1s2 csn2 csn3 driven elf5 factorial focusing greatest incubated jak lys met methionine milk mm mtor optimum peak peaked ppm preliminary rapamycin stat stat5 supplemental upregulation
Tagcloud (Difference) ?		adaptive aggregated antiapoptotic assisting cardiomyocyte cardiomyocytes chaperons confers correct crystallin elicit emphasizing folding hsp hsps interplay lumen mini misfolded mitigate myocardium myocytes referred stressed stresses undergo unfolded upr worldwide	casein concentration csn1s1 csn1s2 csn2 csn3 driven elf5 factorial focusing greatest incubated jak lys met methionine milk mm mtor optimum peak peaked ppm preliminary rapamycin stat stat5 supplemental upregulation
Tagcloud (Intersection) ?