DPPA3 and PLEKHG4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DPPA3	PLEKHG4
Description		developmental pluripotency associated 3	pleckstrin homology and RhoGEF domain containing G4
Image			No pdb structure
GO Annotations	Cellular Component	Female Pronucleus Male Pronucleus Nucleus Cytoplasm	Cytoplasm Cytosol Plasma Membrane Extrinsic Component Of Membrane
	Molecular Function	Protein Binding Histone H3K9me2/3 Reader Activity	Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Chromatin Organization Epigenetic Programing Of Female Pronucleus	Axon Guidance Regulation Of Small GTPase Mediated Signal Transduction
Pathways		Chromatin modifications during the maternal to zygotic transition (MZT)	RHOA GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle
Drugs
Diseases
GWAS		Borderline personality disorder ( 28632202) White matter hyperintensities in ischemic stroke ( 26674333)	A body shape index ( 34021172) Heel bone mineral density ( 28869591) High density lipoprotein cholesterol levels ( 33339817) Refractive error ( 32231278) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		15 interacting genes: CFTR DEPDC5 DYNLL1 DYNLL2 HAUS7 IPO5 KRT27 KRT76 NUP62 PLEKHG4 SERTAD3 SYCE1L TFIP11 TRIB3 ZNF618	65 interacting genes: A1CF ARHGEF5 ARMC7 BEX2 CCDC120 CCDC187 CDC42 CDKN2C CHIC2 COIL DCUN1D5 DPPA3 DTX2 DUSP13B FAM161A FGD2 GATA3 GCM2 GSTZ1 HCK HOXB9 HOXC8 KRT3 KRT75 MALSU1 MATR3 MDFI METAP1 MSRB3 MTA1 MYEF2 MYOZ1 NATD1 OTX1 PFKFB1 PKP2 PRPF18 PRPF31 PSMB1 RHOA RIN1 SAXO1 SAXO4 SETD5 SH2D4A SHISA6 SIX1 SMCP SMG9 TBC1D22B TBX18 TEKT3 TENT5D TFAP2D TFG TRIM55 TRIM63 TSSK3 TTC23 USP2 VPS37C ZCCHC14 ZNF148 ZNF319 ZNF648
Entrez ID		359787	25894
HPRD ID		16331	10890
Ensembl ID		ENSG00000187569	ENSG00000196155
Uniprot IDs		Q6W0C5	A0A024R6X4 Q58EX7
PDB IDs		8WMS 8XV7 8XV8
Enriched GO Terms of Interacting Partners?			Protein Binding Regulation Of Podosome Assembly Positive Regulation Of Ureteric Bud Formation
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