DPPA3 and ZNF618

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DPPA3	ZNF618
Description		developmental pluripotency associated 3	zinc finger protein 618
Image			No pdb structure
GO Annotations	Cellular Component	Female Pronucleus Male Pronucleus Nucleus Cytoplasm	Chromatin Nucleus Chromosome Pericentric Heterochromatin
	Molecular Function	Protein Binding Histone H3K9me2/3 Reader Activity	Transcription Coregulator Binding DNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding Chromatin-protein Adaptor Activity
	Biological Process	Chromatin Organization Epigenetic Programing Of Female Pronucleus	Chromatin Organization Regulation Of Transcription By RNA Polymerase II
Pathways		Chromatin modifications during the maternal to zygotic transition (MZT)
Drugs
Diseases
GWAS		Borderline personality disorder ( 28632202) White matter hyperintensities in ischemic stroke ( 26674333)	Adventurousness ( 30643258) Chronotype ( 30696823) Cognitive function in longevity ( 33607172) Coronary artery aneurysm in Kawasaki disease ( 27171184) Femur bone mineral density x serum urate levels interaction ( 34046847) General risk tolerance (MTAG) ( 30643258) Low density lipoprotein cholesterol levels ( 30498476) Neutrophil level response to clozapine in treatment-resistant schizophrenia ( 30647433) Pulse pressure ( 30224653 30578418) Serum metabolite concentrations in chronic kidney disease ( 29545352) Systolic blood pressure ( 30578418) Tea consumption ( 31046077)
Interacting Genes		15 interacting genes: CFTR DEPDC5 DYNLL1 DYNLL2 HAUS7 IPO5 KRT27 KRT76 NUP62 PLEKHG4 SERTAD3 SYCE1L TFIP11 TRIB3 ZNF618	12 interacting genes: CSNK1D CSNK1E DPPA3 G3BP2 MID1 NTAQ1 RIIAD1 TBC1D13 TPTEP2-CSNK1E UBE2I UBL5 UHRF2
Entrez ID		359787	114991
HPRD ID		16331	18719
Ensembl ID		ENSG00000187569	ENSG00000157657
Uniprot IDs		Q6W0C5	Q5T7W0
PDB IDs		8WMS 8XV7 8XV8
Enriched GO Terms of Interacting Partners?			Positive Regulation Of Non-canonical Wnt Signaling Pathway SUMO Transferase Activity Histone H3K9me2/3 Reader Activity Regulation Of Non-canonical Wnt Signaling Pathway Protein Modification Process Protein Localization To Cytoskeleton Protein Sumoylation SUMO Conjugating Enzyme Activity Protein-N-terminal Glutamine Amidohydrolase Activity Circadian Regulation Of Gene Expression Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein-N-terminal Asparagine Amidohydrolase Activity Positive Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Circadian Rhythm Positive Regulation Of Proteasomal Protein Catabolic Process RING-like Zinc Finger Domain Binding SUMO Ligase Complex HLH Domain Binding Epigenetic Programing Of Female Pronucleus
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