PRDX2 and NLGN3

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		PRDX2	NLGN3
Gene Name		peroxiredoxin 2	neuroligin 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Extracellular Vesicular Exosome	Extracellular Space Integral Component Of Plasma Membrane Cell Surface Cell Junction Endocytic Vesicle Synapse Excitatory Synapse
	Molecular Function	Thioredoxin Peroxidase Activity Antioxidant Activity	Receptor Activity Protein Binding Neurexin Family Protein Binding Cell Adhesion Molecule Binding Carboxylic Ester Hydrolase Activity
	Biological Process	Response To Reactive Oxygen Species Response To Oxidative Stress Removal Of Superoxide Radicals Cellular Response To Oxidative Stress Hydrogen Peroxide Catabolic Process Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Neuron Apoptotic Process Oxidation-reduction Process	Regulation Of Respiratory Gaseous Exchange By Neurological System Process Receptor-mediated Endocytosis Neuron Cell-cell Adhesion Synapse Assembly Learning Metabolic Process Visual Learning Adult Behavior Social Behavior Axon Extension Oligodendrocyte Differentiation Regulation Of Synaptic Transmission Synapse Organization Positive Regulation Of Synapse Assembly Positive Regulation Of Synaptic Transmission, Glutamatergic Rhythmic Synaptic Transmission Regulation Of Inhibitory Postsynaptic Membrane Potential Regulation Of Dendritic Spine Morphogenesis Vocalization Behavior Postsynaptic Membrane Assembly Presynaptic Membrane Assembly Regulation Of Long-term Synaptic Potentiation Regulation Of N-methyl-D-aspartate Selective Glutamate Receptor Activity Regulation Of Terminal Button Organization Positive Regulation Of Excitatory Postsynaptic Membrane Potential Positive Regulation Of Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Activity
Pathways		Detoxification of Reactive Oxygen Species
Drugs		3-Sulfinoalanine N-Carbamoyl-Alanine
Diseases
GWAS
Protein-Protein Interactions		23 interactors: A2M APOE APP BAD CA4 CD320 CDC37 COPS5 ECSIT EXOC6 IFIT5 MAST1 NLGN3 PDGFRB PPP2R1A PPP2R1B PRDX4 PSEN1 RNF32 SAT1 SUMO4 UTY YWHAZ	8 interactors: DLG2 DLG3 DLG4 MEOX2 NRXN1 NRXN2 NRXN3 PRDX2
Entrez ID		7001	54413
HPRD ID		02763	02275
Ensembl ID		ENSG00000167815	ENSG00000196338
Uniprot IDs		A6NIW5 B4DF70 P32119	D3DVV1 Q4G160 Q9NZ94
PDB IDs		1QMV
Enriched GO Terms of Interacting Partners?		Exocytosis Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Signal Transduction Regulation Of Signaling Establishment Of Localization In Cell Secretion By Cell Regulation Of Kinase Activity Regulation Of Phosphorylation Positive Regulation Of Cell Death Secretion Intracellular Signal Transduction Cellular Localization Cellular Component Assembly Vesicle-mediated Transport Regulation Of Cellular Component Organization Regulation Of Phosphorus Metabolic Process Positive Regulation Of Apoptotic Signaling Pathway Response To Oxidative Stress Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Protein Kinase Activity Synapse Assembly Protein Metabolic Process Positive Regulation Of Signal Transduction Membrane Organization Immune Response Regulation Of MAP Kinase Activity Positive Regulation Of Proteolysis Regulation Of Catalytic Activity Homeostatic Process Anatomical Structure Morphogenesis Positive Regulation Of Apoptotic Process Regulation Of Receptor Activity Positive Regulation Of Programmed Cell Death Apoptotic Process Regulation Of MAPK Cascade Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Regulation Of Cellular Protein Metabolic Process Regulation Of Apoptotic Process Programmed Cell Death Developmental Process Cell Death Anion Transport Regulation Of Proteolysis Death Regulation Of Epidermal Growth Factor-activated Receptor Activity Regulation Of Protein Phosphorylation Regulation Of Cell Death Mitochondrial Transport Postsynaptic Membrane Organization Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway	Receptor Localization To Synapse Vocalization Behavior Protein Localization To Synapse Social Behavior Receptor Clustering Synapse Assembly Synaptic Transmission Neuron Cell-cell Adhesion Protein Localization To Membrane Postsynaptic Membrane Organization Learning Cell-cell Signaling Neuroligin Clustering Synapse Organization Gephyrin Clustering Nucleotide Phosphorylation Vocal Learning Regulation Of Grooming Behavior Learning Or Memory Postsynaptic Membrane Assembly Cognition Postsynaptic Density Protein 95 Clustering Membrane Organization Auditory Behavior Neurotransmitter Secretion Axon Guidance Positive Regulation Of Synapse Maturation Single-organism Behavior Regulation Of Neurotransmitter Levels Regulation Of Synapse Maturation Secretion By Cell Neurological System Process Mechanosensory Behavior Axonogenesis Response To Auditory Stimulus Neurotransmitter Transport Adult Behavior Regulation Of N-methyl-D-aspartate Selective Glutamate Receptor Activity Nervous System Development Membrane Assembly Axon Development Cell Morphogenesis Involved In Neuron Differentiation Behavior Cellular Localization Chemotaxis Cellular Protein Localization Membrane Biogenesis Secretion Neuron Projection Morphogenesis Establishment Or Maintenance Of Apical/basal Cell Polarity
Tagcloud ?		2de angustifolia apoa1 atp5a1 atp5a1were bioinformatics caliber david diminishing dysregulated histopathology hspa5 kegg la lavandula lavender le likewise ontology operate pharmaceutically predictedinteractions scrutinized searching slowing snca string sum tof	88mm alcohol chip chromosomes cpg cyp4f13 defect deficit elavl2 epityper fasd hist1h3d igf2r imprinted imprinting islands landscape medip methylation neurofacial neurulation olfaction remarkably retardation sequenom sim1 sox21 tightly tube
Tagcloud (Difference) ?		2de angustifolia apoa1 atp5a1 atp5a1were bioinformatics caliber david diminishing dysregulated histopathology hspa5 kegg la lavandula lavender le likewise ontology operate pharmaceutically predictedinteractions scrutinized searching slowing snca string sum tof	88mm alcohol chip chromosomes cpg cyp4f13 defect deficit elavl2 epityper fasd hist1h3d igf2r imprinted imprinting islands landscape medip methylation neurofacial neurulation olfaction remarkably retardation sequenom sim1 sox21 tightly tube
Tagcloud (Intersection) ?