RALYL and THAP1

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
HPRD (two hybrid)

		RALYL	THAP1
Description		RALY RNA binding protein like	THAP domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Chromatin Fibrillar Center Nucleus Nucleoplasm PML Body
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding Identical Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Identical Protein Binding Protein Homodimerization Activity Sequence-specific DNA Binding Metal Ion Binding
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II Endothelial Cell Proliferation DNA-templated Transcription Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Regulation Of Mitotic Cell Cycle
Pathways
Drugs
Diseases			Primary torsion dystonia (PTD)
GWAS		Adult body size ( 32376654) Body mass index ( 25673413 28892062) Diastolic blood pressure ( 27841878) General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Night sleep phenotypes ( 27126917) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Systolic blood pressure ( 27841878) Trunk fat mass ( 28552196)	Pelvic organ prolapse (moderate/severe) ( 26545240)
Interacting Genes		25 interacting genes: ADISSP AEBP2 AEN BYSL CAMK2A CCDC85B CEP170P1 EWSR1 EXOSC7 FXR1 FXR2 HNRNPC LMO3 LRRK2 MBD2 MCRS1 NXF1 PCBP2 PSMF1 RBM41 THAP1 TIGD3 TSC1 TSNAX ZNF408	105 interacting genes: ABCF3 ACOT7 AEBP2 AKAP17A AKAP9 AP2B1 APP ARL6IP4 BAG5 BEND7 BMS1P1 BYSL C1orf216 C1orf35 CDC37 CDKN2D CHD2 CHLSN CSNK2A1 DCAF8 DRC4 DVL2 FAM124A FAM133A FAM9A FGF10 FGF11 FGF12 FXR2 GPATCH2L HNRNPLL HYPK INO80B KANK2 KLF12 KRTAP10-7 L3MBTL2 LASP1 LMNB2 LMO3 LNX1 METTL13 MFAP1 MIS18A MORF4L1 MORF4L2 MRPL11 MRPL53 NDUFAB1 NKAP NKAPD1 NTAQ1 NUP62 PAWR PHF1 PHF19 PID1 PNKP POLR2L POLR2M POU6F2 PPIG PRKAA1 PRR20A PRR20B PRR20C PRR20D PRR20E QKI RAD54L2 RALY RALYL RBM10 RBM39 RIPPLY1 RNF4 RP9P RPL22 RPS25 SAP30BP SERF2 SLU7 SPANXN2 SPMIP2 SREK1IP1 STRBP TCEA2 TCEANC TPM3 TRAF5 TRIM26 TRIP10 TTLL10 TXN2 U2AF2 UBE2I VCX2 WT1 YES1 ZBTB48 ZCCHC10 ZGPAT ZNF385C ZNF408 ZNF526
Entrez ID		138046	55145
HPRD ID		11236	15496
Ensembl ID		ENSG00000184672	ENSG00000131931
Uniprot IDs		B3KT61 Q86SE5	Q9NVV9
PDB IDs			2JTG 2KO0 2L1G
Enriched GO Terms of Interacting Partners?		Nucleic Acid Binding Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Nucleus RNA Binding MRNA Binding Negative Regulation Of Metabolic Process Positive Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Neuronal Synaptic Plasticity Negative Regulation Of Macromolecule Metabolic Process Regulation Of Protein Localization To Nucleolus Regulation Of Gene Expression Regulation Of Metabolic Process Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Catabolic Process Regulation Of Macromolecule Metabolic Process Translation Regulator Activity Cytoplasmic Stress Granule Nucleoplasm Regulation Of RNA Metabolic Process Protein Homodimerization Activity Poly(U) RNA Binding Identical Protein Binding Negative Regulation Of Macromolecule Biosynthetic Process Dentate Gyrus Development Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Nucleobase-containing Compound Metabolic Process MRNA 3'-UTR Binding Negative Regulation Of Biosynthetic Process Negative Regulation Of Telomere Maintenance Via Telomere Lengthening MRNA 3'-UTR AU-rich Region Binding MRNA Transport Regulation Of Primary Metabolic Process RNA Processing Negative Regulation Of Hydrolase Activity Peptidyl-threonine Autophosphorylation Neuron Projection Negative Regulation Of Telomere Maintenance Memory T Cell Differentiation Negative Regulation Of Macroautophagy RNA Transport Cellular Response To Curcumin Caveola Neck GTP-dependent Protein Kinase Activity Wnt Signalosome Assembly Nucleosomal DNA Binding Presynaptic Modulation Of Chemical Synaptic Transmission Nucleolus Regulation Of Telomere Maintenance Via Telomere Lengthening Regulation Of MRNA Stability U12 SnRNA Binding	Nucleus RNA Splicing Nucleic Acid Binding RNA Binding Protein Binding MRNA Processing Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process PTB Domain Binding ESC/E(Z) Complex Regulation Of Nucleobase-containing Compound Metabolic Process RNA Processing MRNA Metabolic Process Positive Regulation Of Fat Cell Proliferation
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