COX5B and KRT27

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		COX5B	KRT27
Description		cytochrome c oxidase subunit 5B	keratin 27
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Envelope Mitochondrial Inner Membrane Membrane Mitochondrial Membrane Respiratory Chain Complex IV	Cytoplasm Cytosol Cytoskeleton Intermediate Filament Keratin Filament Extracellular Exosome
	Molecular Function	Cytochrome-c Oxidase Activity Protein Binding Metal Ion Binding	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Oxidative Phosphorylation Mitochondrial Electron Transport, Cytochrome C To Oxygen Respiratory Gaseous Exchange By Respiratory System Cellular Respiration Proton Transmembrane Transport	Morphogenesis Of An Epithelium Epithelial Cell Differentiation Hair Follicle Morphogenesis Intermediate Filament Organization
Pathways		TP53 Regulates Metabolic Genes Respiratory electron transport Cytoprotection by HMOX1 Mitochondrial protein degradation Complex IV assembly	Keratinization Formation of the cornified envelope
Drugs		Cholic Acid N-Formylmethionine
Diseases
GWAS		Bipolar disorder ( 31043756) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Asthma ( 31959851)
Interacting Genes		35 interacting genes: AR ARID5A BHLHE40 CDC42EP2 CDR2 CDR2L DOK3 FAM228A FLOT1 GOLGA2 IHO1 KRT15 KRT27 KRT31 KRT33B LSM4 MCCD1 MID2 NUDT5 OIP5 PLEKHF2 PNMA1 PRDM6 PRKAR1B PRR22 RBM48 SAXO4 SLAIN1 TASOR2 TEX12 TFIP11 TRAF1 TRIM23 TRIM27 VPS28	139 interacting genes: AARD ABI2 AMOT ARFIP1 ARHGEF6 ATP6V1D BCAS2 BEX2 BFSP2 C19orf44 C1orf216 C21orf58 CCBE1 CCDC138 CCDC146 CCDC185 CCDC187 CCDC22 CCDC68 CCHCR1 CCNC CEP95 CFAP58 COX5B DPPA3 DTNB DUSP26 EXOC3L1 EXOSC5 FAM107A FAM110A FMNL2 GADD45GIP1 GFAP GNG13 GOLGA1 GPS2 GSTK1 HAPLN2 HDAC4 HGS HOXB9 HSPBP1 ICA1L IGF1R INSR INSRR JOSD1 KANK2 KIAA1217 KLHL38 KRT1 KRT2 KRT20 KRT3 KRT4 KRT5 KRT6A KRT6B KRT6C KRT7 KRT71 KRT72 KRT74 KRT75 KRT76 KRT77 KRT78 KRT79 KRT8 KRT81 KRT82 KRT83 KRT85 KRT86 LKAAEAR1 LMNTD2 MATR3 MBD3L2 MID2 MORN4 MOS MTMR9 NDC80 NDUFAF3 NTAQ1 NUP54 NUP58 ODAD3 OIP5 PBX3 PCDHB14 PNN POLL PPP1R18 PRPH PSMC5 RASAL3 RBM41 RCOR3 RNF39 RTP5 RUNX1T1 SCNM1 SDHAF1 SEMA4C SLC22A5 SLIRP SMARCC2 SMARCD1 SMARCE1 SSC5D SSX3 SUFU SUOX TBRG4 TEAD4 TEDC2 TEX28 THAP7 TNNT1 TRAF3IP3 TRIML2 TSKS TTC23 TXLNB TXN2 USHBP1 USP2 VPS37C WASHC3 XRCC4 ZC3H14 ZFYVE26 ZNF3 ZNF580 ZNF581 ZNF669 ZNF80
Entrez ID		1329	342574
HPRD ID		00467	17244
Ensembl ID		ENSG00000135940	ENSG00000171446
Uniprot IDs		A0A384NL93 P10606	Q7Z3Y8
PDB IDs		5Z62
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Structural Molecule Activity Keratin Filament Intermediate Filament-based Process Intermediate Filament Organization Supramolecular Fiber Organization Organelle Organization Intermediate Filament Cellular Response To Estrogen Stimulus Morphogenesis Of An Epithelium Cytoskeleton Suppression Of Viral Release By Host Negative Regulation Of Viral Transcription Cytoskeleton Organization Regulation Of Viral Transcription	Intermediate Filament Organization Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Keratinization Keratin Filament Supramolecular Fiber Organization Cytoskeleton Organization Protein Binding Organelle Organization Insulin Receptor Activity Structural Constituent Of Cytoskeleton Insulin Receptor Complex Intermediate Filament Cytoskeleton Structural Molecule Activity Insulin Receptor Substrate Binding Epidermis Development Brahma Complex NpBAF Complex RSC-type Complex NBAF Complex Phosphatidylinositol 3-kinase Binding Nucleosome Disassembly Insulin Binding
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