KRT27 and SSC5D

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRT27	SSC5D
Description		keratin 27	scavenger receptor cysteine rich family member with 5 domains
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Intermediate Filament Keratin Filament Extracellular Exosome	Extracellular Region Extracellular Space Cytoplasm Membrane Extracellular Matrix
	Molecular Function	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis	Fibronectin Binding Scavenger Receptor Activity Protein Binding Laminin Binding Extracellular Matrix Binding
	Biological Process	Morphogenesis Of An Epithelium Epithelial Cell Differentiation Hair Follicle Morphogenesis Intermediate Filament Organization	Immune System Process Defense Response Vesicle-mediated Transport Regulation Of Interleukin-8 Production Negative Regulation Of Interleukin-8 Production Detection Of Bacterial Lipoprotein Innate Immune Response Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium
Pathways		Keratinization Formation of the cornified envelope	Scavenging by Class B Receptors
Drugs
Diseases
GWAS		Asthma ( 31959851)	Height ( 28552196) Lung adenocarcinoma ( 28604730)
Interacting Genes		139 interacting genes: AARD ABI2 AMOT ARFIP1 ARHGEF6 ATP6V1D BCAS2 BEX2 BFSP2 C19orf44 C1orf216 C21orf58 CCBE1 CCDC138 CCDC146 CCDC185 CCDC187 CCDC22 CCDC68 CCHCR1 CCNC CEP95 CFAP58 COX5B DPPA3 DTNB DUSP26 EXOC3L1 EXOSC5 FAM107A FAM110A FMNL2 GADD45GIP1 GFAP GNG13 GOLGA1 GPS2 GSTK1 HAPLN2 HDAC4 HGS HOXB9 HSPBP1 ICA1L IGF1R INSR INSRR JOSD1 KANK2 KIAA1217 KLHL38 KRT1 KRT2 KRT20 KRT3 KRT4 KRT5 KRT6A KRT6B KRT6C KRT7 KRT71 KRT72 KRT74 KRT75 KRT76 KRT77 KRT78 KRT79 KRT8 KRT81 KRT82 KRT83 KRT85 KRT86 LKAAEAR1 LMNTD2 MATR3 MBD3L2 MID2 MORN4 MOS MTMR9 NDC80 NDUFAF3 NTAQ1 NUP54 NUP58 ODAD3 OIP5 PBX3 PCDHB14 PNN POLL PPP1R18 PRPH PSMC5 RASAL3 RBM41 RCOR3 RNF39 RTP5 RUNX1T1 SCNM1 SDHAF1 SEMA4C SLC22A5 SLIRP SMARCC2 SMARCD1 SMARCE1 SSC5D SSX3 SUFU SUOX TBRG4 TEAD4 TEDC2 TEX28 THAP7 TNNT1 TRAF3IP3 TRIML2 TSKS TTC23 TXLNB TXN2 USHBP1 USP2 VPS37C WASHC3 XRCC4 ZC3H14 ZFYVE26 ZNF3 ZNF580 ZNF581 ZNF669 ZNF80	17 interacting genes: BLOC1S2 CEP170P1 DTNBP1 EXOC7 HAUS1 KRT27 MED11 MED21 MED29 NECAB2 NUP62 PIN1 SDCBP SEC23IP SKA1 TCEA2 TRAF1
Entrez ID		342574	284297
HPRD ID		17244	11444
Ensembl ID		ENSG00000171446	ENSG00000179954
Uniprot IDs		Q7Z3Y8	A1L4H1
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Organization Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Keratinization Keratin Filament Supramolecular Fiber Organization Cytoskeleton Organization Protein Binding Organelle Organization Insulin Receptor Activity Structural Constituent Of Cytoskeleton Insulin Receptor Complex Intermediate Filament Cytoskeleton Structural Molecule Activity Insulin Receptor Substrate Binding Epidermis Development Brahma Complex NpBAF Complex RSC-type Complex NBAF Complex Phosphatidylinositol 3-kinase Binding Nucleosome Disassembly Insulin Binding	Regulation Of DNA-templated Transcription Elongation Core Mediator Complex Cytoskeleton Organization Cellular Component Assembly RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of Transcription Elongation By RNA Polymerase II Mediator Complex Positive Regulation Of Mitotic Cytokinetic Process Positive Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Transcription Initiation By RNA Polymerase II Transcription Preinitiation Complex Assembly Regulation Of Receptor Internalization Positive Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Initiation By RNA Polymerase II Regulation Of DNA-templated Transcription Initiation Positive Regulation Of Mitotic Cytokinesis Organelle Localization Regulation Of Cytokinesis Microtubule-based Process Regulation Of Mitotic Cytokinesis BLOC-1 Complex Negative Regulation Of Receptor Internalization Regulation Of Transcription Elongation By RNA Polymerase II Mitotic Spindle Microtubule Anterograde Synaptic Vesicle Transport Regulation Of Mitotic Nuclear Division Regulation Of Receptor-mediated Endocytosis Organelle Organization Transcription Coregulator Activity Platelet Dense Granule Organization Centrosome Regulation Of Nuclear Division Negative Regulation Of Receptor-mediated Endocytosis Flemming Body Regulation Of Microtubule Cytoskeleton Organization Synaptic Vesicle Transport Melanosome Organization Pigment Granule Organization Regulation Of Cell Division Midbody Protein-DNA Complex Assembly Positive Regulation Of Cytokinesis Microtubule Cytoskeleton Organization Anterograde Axonal Transport Cis-trans Isomerase Activity Interleukin-5 Receptor Complex Positive Regulation Of Mitotic Nuclear Division Mitotic Metaphase Chromosome Alignment Vesicle Transport Along Microtubule Establishment Of Protein Localization
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