COX5B and PRR22

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		COX5B	PRR22
Description		cytochrome c oxidase subunit 5B	proline rich 22
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Envelope Mitochondrial Inner Membrane Membrane Mitochondrial Membrane Respiratory Chain Complex IV
	Molecular Function	Cytochrome-c Oxidase Activity Protein Binding Metal Ion Binding
	Biological Process	Oxidative Phosphorylation Mitochondrial Electron Transport, Cytochrome C To Oxygen Respiratory Gaseous Exchange By Respiratory System Cellular Respiration Proton Transmembrane Transport
Pathways		TP53 Regulates Metabolic Genes Respiratory electron transport Cytoprotection by HMOX1 Mitochondrial protein degradation Complex IV assembly
Drugs		Cholic Acid N-Formylmethionine
Diseases
GWAS		Bipolar disorder ( 31043756) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		35 interacting genes: AR ARID5A BHLHE40 CDC42EP2 CDR2 CDR2L DOK3 FAM228A FLOT1 GOLGA2 IHO1 KRT15 KRT27 KRT31 KRT33B LSM4 MCCD1 MID2 NUDT5 OIP5 PLEKHF2 PNMA1 PRDM6 PRKAR1B PRR22 RBM48 SAXO4 SLAIN1 TASOR2 TEX12 TFIP11 TRAF1 TRIM23 TRIM27 VPS28	26 interacting genes: CDC23 COX5B CREB5 CRYBA2 CRYBA4 CYSRT1 DOK6 FOXH1 GPS2 GRB2 HGS HNRNPF KCTD7 KRTAP26-1 MKRN3 NELFA OTX1 PATZ1 PPIL1 SMYD1 SNRPB TFAP2D TNS2 TRAPPC6A UFSP1 VGLL3
Entrez ID		1329	163154
HPRD ID		00467	14501
Ensembl ID		ENSG00000135940	ENSG00000212123
Uniprot IDs		A0A384NL93 P10606	Q8IZ63
PDB IDs		5Z62
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Structural Molecule Activity Keratin Filament Intermediate Filament-based Process Intermediate Filament Organization Supramolecular Fiber Organization Organelle Organization Intermediate Filament Cellular Response To Estrogen Stimulus Morphogenesis Of An Epithelium Cytoskeleton Suppression Of Viral Release By Host Negative Regulation Of Viral Transcription Cytoskeleton Organization Regulation Of Viral Transcription
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