KRT27 and KRT75

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRT27	KRT75
Description		keratin 27	keratin 75
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Intermediate Filament Keratin Filament Extracellular Exosome	Cornified Envelope Cytosol Intermediate Filament Keratin Filament Extracellular Exosome
	Molecular Function	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Morphogenesis Of An Epithelium Epithelial Cell Differentiation Hair Follicle Morphogenesis Intermediate Filament Organization	Hematopoietic Progenitor Cell Differentiation Keratinization Intermediate Filament Organization
Pathways		Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs
Diseases			Pseudofolliculitis barbae
GWAS		Asthma ( 31959851)
Interacting Genes		139 interacting genes: AARD ABI2 AMOT ARFIP1 ARHGEF6 ATP6V1D BCAS2 BEX2 BFSP2 C19orf44 C1orf216 C21orf58 CCBE1 CCDC138 CCDC146 CCDC185 CCDC187 CCDC22 CCDC68 CCHCR1 CCNC CEP95 CFAP58 COX5B DPPA3 DTNB DUSP26 EXOC3L1 EXOSC5 FAM107A FAM110A FMNL2 GADD45GIP1 GFAP GNG13 GOLGA1 GPS2 GSTK1 HAPLN2 HDAC4 HGS HOXB9 HSPBP1 ICA1L IGF1R INSR INSRR JOSD1 KANK2 KIAA1217 KLHL38 KRT1 KRT2 KRT20 KRT3 KRT4 KRT5 KRT6A KRT6B KRT6C KRT7 KRT71 KRT72 KRT74 KRT75 KRT76 KRT77 KRT78 KRT79 KRT8 KRT81 KRT82 KRT83 KRT85 KRT86 LKAAEAR1 LMNTD2 MATR3 MBD3L2 MID2 MORN4 MOS MTMR9 NDC80 NDUFAF3 NTAQ1 NUP54 NUP58 ODAD3 OIP5 PBX3 PCDHB14 PNN POLL PPP1R18 PRPH PSMC5 RASAL3 RBM41 RCOR3 RNF39 RTP5 RUNX1T1 SCNM1 SDHAF1 SEMA4C SLC22A5 SLIRP SMARCC2 SMARCD1 SMARCE1 SSC5D SSX3 SUFU SUOX TBRG4 TEAD4 TEDC2 TEX28 THAP7 TNNT1 TRAF3IP3 TRIML2 TSKS TTC23 TXLNB TXN2 USHBP1 USP2 VPS37C WASHC3 XRCC4 ZC3H14 ZFYVE26 ZNF3 ZNF580 ZNF581 ZNF669 ZNF80	119 interacting genes: - ABI2 AIRIM AMOT ANKS1A ARMC7 ASB15 BCAS2 BEX2 C19orf25 C1orf216 CAMK2A CARD10 CARD9 CATSPERT CCDC102B CCDC197 CCHCR1 CDC37 CDK18 CDKN2D CEP57 CFAP206 CPNE7 CRACR2A DHX15 DMAP1 DTNBP1 DYDC1 EFHC1 EPM2AIP1 FBXO17 FKBP6 GLYCTK GMCL1 GOLGA2 GOLGA6L9 GPANK1 HGS HNRNPF INCA1 IQUB KANK2 KCTD7 KIF9 KIFC3 KRT13 KRT20 KRT24 KRT25 KRT26 KRT27 KRT31 KRT32 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT40 KRT76 LCA5L LMO1 LMO2 LMO4 LONRF1 MAGOHB MID2 MKRN3 MNS1 MTUS2 MYO15B MYOZ3 NCDN NDC80 NEK6 NFKBID NME7 NUDT21 NUP62 OIP5 OSGIN1 PLEKHG4 PM20D2 POLR1C POLR3C RCOR3 RSPH14 SCNM1 SMARCD1 SPAG5 SPTA1 STX11 SUFU TBC1D1 TCHP TEKT1 TEKT4 TJAP1 TNPO2 TNPO3 TRAF1 TRIM23 TRIM27 TRIM54 TRIML2 TSG101 TSSK3 TXLNA TXLNB U2AF1 USHBP1 WASHC1 WASHC3 WWOX XPOT ZNF76 ZWINT
Entrez ID		342574	9119
HPRD ID		17244	11057
Ensembl ID		ENSG00000171446	ENSG00000170454
Uniprot IDs		Q7Z3Y8	O95678
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Organization Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Keratinization Keratin Filament Supramolecular Fiber Organization Cytoskeleton Organization Protein Binding Organelle Organization Insulin Receptor Activity Structural Constituent Of Cytoskeleton Insulin Receptor Complex Intermediate Filament Cytoskeleton Structural Molecule Activity Insulin Receptor Substrate Binding Epidermis Development Brahma Complex NpBAF Complex RSC-type Complex NBAF Complex Phosphatidylinositol 3-kinase Binding Nucleosome Disassembly Insulin Binding	Structural Constituent Of Skin Epidermis Intermediate Filament Organization Keratin Filament Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Cytoskeleton Structural Molecule Activity Supramolecular Fiber Organization Cytoskeleton Organization Protein Binding Morphogenesis Of An Epithelium Epithelial Cell Differentiation Tissue Morphogenesis Motile Cilium Organelle Organization Axonemal A Tubule Inner Sheath Radial Spoke Microtubule-based Process Sperm Flagellum Axonemal Microtubule Cytoplasm Microtubule-based Movement Flagellated Sperm Motility Sperm Motility Cytosol Cilium-dependent Cell Motility Cilium Movement Cilium Movement Involved In Cell Motility Cilium Identical Protein Binding Microtubule Binding Regulation Of Actin Nucleation Microtubule Regulation Of Organelle Organization Spliceosomal Complex CBM Complex Centrosome Regulation Of Arp2/3 Complex-mediated Actin Nucleation Phosphatidylinositol 3-kinase Inhibitor Activity Polymeric Cytoskeletal Fiber Spindle Organization
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