ZNF473 and SLBP

Number of citations of the paper that reports this interaction (PubMedID 11782445)
69

Data Source:
HPRD (two hybrid, in vitro)

		ZNF473	SLBP
Description		zinc finger protein 473	stem-loop histone mRNA binding protein
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cajal Body	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Histone MRNA Stem-loop Binding Complex Histone Pre-mRNA 3'end Processing Complex Ribonucleoprotein Complex
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	RNA Binding MRNA Binding Protein Binding Identical Protein Binding Histone Pre-mRNA Stem-loop Binding Histone Pre-mRNA DCP Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II MRNA 3'-end Processing By Stem-loop Binding And Cleavage	Cap-dependent Translational Initiation MRNA Processing MRNA 3'-end Processing By Stem-loop Binding And Cleavage MRNA Transport
Pathways		SLBP independent Processing of Histone Pre-mRNAs Generic Transcription Pathway RNA Polymerase II Transcription Termination SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs	Transport of the SLBP Dependant Mature mRNA RNA Polymerase II Transcription Termination SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
Drugs
Diseases
GWAS			Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Hip circumference adjusted for BMI ( 25673412 34021172) Hip index ( 34021172) Hip minimal joint space width ( 27701424) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Mean reticulocyte volume ( 32888494) Metabolite levels ( 23823483) Subcortical volume (MOSTest) ( 32665545) Urinary bladder cancer ( 20348956)
Interacting Genes		22 interacting genes: AEN APP CLK2 CLK3 DHX57 GPATCH2L KRTAP10-10 KRTAP10-8 KRTAP10-9 LSM11 PRPF31 RBM10 RNPS1 SLBP TRIM41 ZNF202 ZNF250 ZNF408 ZNF497 ZNF792 ZNF837 ZSCAN12	12 interacting genes: CDK1 CDK2 CDK4 CDK6 CEBPA CSNK2A1 DCAF11 ERI1 LSM10 PTGER4 USP8 ZNF473
Entrez ID		25888	7884
HPRD ID		11721	03884
Ensembl ID		ENSG00000142528	ENSG00000163950
Uniprot IDs		B4DY71 F8WEC7 Q8WTR7	B3KSC5 B3KST9 B4DUW7 E7EUV9 Q14493 Q53XR2
PDB IDs		2EMB 2EMC 2EME 2EOU 2EOX 2EOY 2EOZ 2YRH 2YRJ 2YSV 2YTD 2YTE 2YTT 2YU5 9AZI	2KJM 4L8R 4QOZ
Enriched GO Terms of Interacting Partners?		Identical Protein Binding PTB Domain Binding Nucleus MRNA 3'-end Processing By Stem-loop Binding And Cleavage Histone Pre-mRNA 3'end Processing Complex Regulation Of RNA Splicing Zinc Ion Binding Nuclear Speck RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding MRNA Processing Keratin Filament Negative Regulation Of MRNA Splicing, Via Spliceosome Histone MRNA Metabolic Process Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of Response To Calcium Ion Amylin Binding Regulation Of Gene Expression Positive Regulation Of Toll Signaling Pathway Protein Serine/threonine/tyrosine Kinase Activity RNA Processing MRNA 3'-end Processing MRNA Metabolic Process Vascular Associated Smooth Muscle Cell Apoptotic Process Negative Regulation Of Ribosomal Large Subunit Export From Nucleus Negative Regulation Of RNA Splicing Ribonucleoprotein Complex Localization Intermediate Filament Ribonucleoprotein Complex	Cyclin Binding Cyclin-dependent Protein Serine/threonine Kinase Activity Cyclin-dependent Protein Kinase Holoenzyme Complex Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle Phase Transition Histone MRNA Metabolic Process Regulation Of G2/M Transition Of Mitotic Cell Cycle Cyclin-dependent Protein Kinase Activity Regulation Of Cell Cycle G2/M Phase Transition Mitotic Cell Cycle Phase Transition Regulation Of Mitotic Cell Cycle Phase Transition Protein Serine Kinase Activity Negative Regulation Of Cell Cycle Cell Cycle Phase Transition Regulation Of Cell Cycle Histone Kinase Activity MRNA 3'-end Processing By Stem-loop Binding And Cleavage Protein Serine/threonine Kinase Activity Regulation Of Cell Cycle Process Cajal Body Response To Ketone Cellular Response To Oxygen-containing Compound Negative Regulation Of Macromolecule Metabolic Process Regulation Of Mitotic Cell Cycle Protein Kinase Activity RNA 3'-end Processing Regulation Of Macromolecule Metabolic Process Nucleic Acid Metabolic Process Positive Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Metabolic Process DNA Damage Checkpoint Signaling Kinase Activity Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cell Cycle Phase Transition Negative Regulation Of Hemopoiesis Macromolecule Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Metabolic Process Positive Regulation Of Mitotic Cell Cycle Nucleoplasm Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of Protein Catabolic Process Protein Localization To Site Of Double-strand Break Intracellular Signal Transduction Regulation Of Transcription By RNA Polymerase II Signal Transduction In Response To DNA Damage Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle DNA Damage Response
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