ZNF473 and DHX57

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ZNF473	DHX57
Gene Name		zinc finger protein 473	DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cajal Body	Nucleus Mitochondrion
	Molecular Function	DNA Binding Protein Binding Metal Ion Binding	ATP-dependent RNA Helicase Activity ATP Binding Poly(A) RNA Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription Histone MRNA 3'-end Processing Histone MRNA Metabolic Process Gene Expression MRNA 3'-end Processing	RNA Processing
Pathways		SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs RNA Polymerase II Transcription Generic Transcription Pathway Processing of Capped Intronless Pre-mRNA Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination SLBP independent Processing of Histone Pre-mRNAs
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		14 interactors: AEN CLK2 DHX57 GPATCH2L KRTAP10-8 KRTAP10-9 LSM11 RNPS1 SLBP TRIM41 ZNF202 ZNF250 ZNF792 ZSCAN12	10 interactors: CBX2 CEP44 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP9-4 ZNF473
Entrez ID		25888	90957
HPRD ID		11721	09919
Ensembl ID		ENSG00000142528	ENSG00000163214
Uniprot IDs		F8WEC7 Q8WTR7	Q6P158 Q8N4U2
PDB IDs		2EMB 2EMC 2EME 2EOU 2EOX 2EOY 2EOZ 2YRH 2YRJ 2YSV 2YTD 2YTE 2YTT 2YU5
Enriched GO Terms of Interacting Partners?		Termination Of RNA Polymerase II Transcription Histone MRNA 3'-end Processing DNA-templated Transcription, Termination MRNA 3'-end Processing RNA Metabolic Process RNA 3'-end Processing Nucleobase-containing Compound Metabolic Process Transcription, DNA-templated Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Histone MRNA Metabolic Process Nitrogen Compound Metabolic Process Cellular Metabolic Process RNA Processing Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process MRNA Export From Nucleus Transcription From RNA Polymerase II Promoter RNA Export From Nucleus MRNA Processing Regulation Of RNA Splicing Nuclear Export MRNA Transport MRNA Metabolic Process RNA Transport Response To Ionizing Radiation Biosynthetic Process RNA Localization Metabolic Process Negative Regulation Of Gluconeogenesis Nucleocytoplasmic Transport Nuclear Transport Regulation Of RNA Metabolic Process Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Nuclear DNA Replication Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Gene Expression Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Nitrogen Compound Metabolic Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Response To Radiation Regulation Of Gluconeogenesis Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator	Histone MRNA 3'-end Processing
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