ZNF526 and GRAP2

Number of citations of the paper that reports this interaction (PubMedID 27107012)
72

Data Source:
BioGRID (two hybrid)

		ZNF526	GRAP2
Description		zinc finger protein 526	GRB2 related adaptor protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Cytoplasm Endosome Cytosol Plasma Membrane
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Phosphotyrosine Residue Binding Protein Binding
	Biological Process		Signal Transduction Ras Protein Signal Transduction Cell-cell Signaling Regulation Of MAPK Cascade
Pathways			Signaling by SCF-KIT Generation of second messenger molecules DAP12 signaling FCERI mediated MAPK activation FCERI mediated Ca+2 mobilization FCERI mediated Ca+2 mobilization Co-stimulation by CD28 FLT3 Signaling Signaling by CSF1 (M-CSF) in myeloid cells
Drugs
Diseases
GWAS		Hodgkin's lymphoma ( 34216518) Meat-related diet ( 32066663)	Body mass index ( 26426971) Systemic lupus erythematosus ( 28714469)
Interacting Genes		54 interacting genes: ATXN7L2 BAHD1 C8orf33 FAM161A FAM90A1 FARS2 GPATCH2L GRAP2 HNRNPK IL16 INO80B IQUB KAT5 LMO1 LMO3 MAPRE3 MRPL11 NCK2 NME7 OVOL2 PADI6 PBK PHF1 PIN1 PRKAB2 PRPF18 RBM10 SCNM1 SEPHS1 SPANXN2 SYCE1L TCEA2 THAP1 THAP12 TRIM41 U2AF2 VCX2 YJU2 ZBTB24 ZFP91 ZNF124 ZNF264 ZNF408 ZNF438 ZNF497 ZNF524 ZNF575 ZNF578 ZNF696 ZNF76 ZNF774 ZNF792 ZNF835 ZNF837	78 interacting genes: AR BAG4 BEND5 BLNK CBL CBLB CBY2 CCHCR1 CCNDBP1 CD28 COG6 CSF1R DNM2 DVL2 EGFR ERBB2 ERBB3 ERBB4 ETV5 FASLG GAB1 GAB2 GAB3 GAREM1 GATA1 GFAP GOLGA2 GRB2 HNRNPK IHO1 IKZF3 KHDRBS1 KHDRBS2 KIT KPRP KRT13 KRTAP1-3 KRTAP4-11 KRTAP4-12 LAT LATS2 LAX1 LCP2 LNX1 LNX2 MAGED1 MAP4K1 MKRN3 MOS MTUS2 PBLD PNMA1 PRKAA2 PRPH2 PRR35 RACK1 RAVER1 RBPMS RIN3 RINT1 SH2D4A SHB SHC1 SOS2 SPRY2 SSX2IP STAMBP TFIP11 TLE5 TRAF1 TSNAXIP1 USP8 WWP2 YWHAE ZBTB7B ZNF250 ZNF319 ZNF526
Entrez ID		116115	9402
HPRD ID		15818	05156
Ensembl ID		ENSG00000167625	ENSG00000100351
Uniprot IDs		H9ZYJ3 Q8TF50	B7Z8E3 B7Z8F8 O75791 Q6FI14
PDB IDs			5GJH
Enriched GO Terms of Interacting Partners?		Zinc Ion Binding Nucleus Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process Metal Ion Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Spliceosomal Complex MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing	Positive Regulation Of Intracellular Signal Transduction Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Cell Surface Receptor Signaling Pathway Regulation Of Programmed Cell Death Regulation Of Intracellular Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Apoptotic Process Regulation Of Signal Transduction Positive Regulation Of Signal Transduction ERBB Signaling Pathway Positive Regulation Of Cell Communication Positive Regulation Of Signaling Signaling Adaptor Activity Enzyme-linked Receptor Protein Signaling Pathway Regulation Of Cell Communication Regulation Of Signaling Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Intracellular Signal Transduction Positive Regulation Of MAPK Cascade SH2 Domain Binding Antigen Receptor-mediated Signaling Pathway Regulation Of MAPK Cascade Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Immune Response-regulating Cell Surface Receptor Signaling Pathway Protein Binding Positive Regulation Of Protein Modification Process Identical Protein Binding Immune Response-activating Cell Surface Receptor Signaling Pathway Response To Growth Factor Signal Transduction Negative Regulation Of Programmed Cell Death Cellular Response To Growth Factor Stimulus Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity Positive Regulation Of Protein Metabolic Process Regulation Of Cell Population Proliferation Positive Regulation Of Protein Phosphorylation Regulation Of Protein Modification Process Lymphocyte Activation Intracellular Signaling Cassette Negative Regulation Of Apoptotic Process Leukocyte Activation Positive Regulation Of Phosphate Metabolic Process Phosphotyrosine Residue Binding Positive Regulation Of Phosphorylation Cellular Response To Epidermal Growth Factor Stimulus Immune Response-regulating Signaling Pathway ERBB2 Signaling Pathway Positive Regulation Of Cell Population Proliferation Transmembrane Receptor Protein Tyrosine Kinase Activity Response To Epidermal Growth Factor
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?