ZNF526 and PADI6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZNF526	PADI6
Description		zinc finger protein 526	peptidyl arginine deiminase 6
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Cytoplasm Cytoplasmic Vesicle Intermediate Filament Cytoskeleton Cortical Granule Cytoplasmic Lattice Ooplasm
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Protein-arginine Deiminase Activity Calcium Ion Binding Protein Binding Tubulin Binding Identical Protein Binding Structural Constituent Of Cytoplasmic Lattice
	Biological Process		In Utero Embryonic Development Cytoskeleton Organization Cytoplasm Organization Intracellular Protein Localization Embryonic Cleavage Regulation Of Translation By Machinery Localization Epigenetic Programming In The Zygotic Pronuclei Protein Storage
Pathways			Chromatin modifying enzymes
Drugs			Citrulline
Diseases
GWAS		Hodgkin's lymphoma ( 34216518) Meat-related diet ( 32066663)	Basal cell carcinoma ( 18849993 24403052 25855136) Mean platelet volume ( 27863252)
Interacting Genes		54 interacting genes: ATXN7L2 BAHD1 C8orf33 FAM161A FAM90A1 FARS2 GPATCH2L GRAP2 HNRNPK IL16 INO80B IQUB KAT5 LMO1 LMO3 MAPRE3 MRPL11 NCK2 NME7 OVOL2 PADI6 PBK PHF1 PIN1 PRKAB2 PRPF18 RBM10 SCNM1 SEPHS1 SPANXN2 SYCE1L TCEA2 THAP1 THAP12 TRIM41 U2AF2 VCX2 YJU2 ZBTB24 ZFP91 ZNF124 ZNF264 ZNF408 ZNF438 ZNF497 ZNF524 ZNF575 ZNF578 ZNF696 ZNF76 ZNF774 ZNF792 ZNF835 ZNF837	3 interacting genes: KLHL2 SUV39H1 ZNF526
Entrez ID		116115	353238
HPRD ID		15818	15095
Ensembl ID		ENSG00000167625	ENSG00000276747
Uniprot IDs		H9ZYJ3 Q8TF50	Q6TGC4
PDB IDs			4DAT 4DAU 8QL0 9FMN
Enriched GO Terms of Interacting Partners?		Zinc Ion Binding Nucleus Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process Metal Ion Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Spliceosomal Complex MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing	Nuclear Lamina Histone H3K9 Trimethyltransferase Activity Histone H3K9me2 Methyltransferase Activity Regulation Of Transcription By Glucose Histone H3K9 Methyltransferase Activity RDNA Heterochromatin Formation ENoSc Complex RDNA Heterochromatin Facultative Heterochromatin Formation Epigenetic Programming In The Zygotic Pronuclei Chromatin Silencing Complex S-adenosylmethionine-dependent Methyltransferase Activity Blastocyst Hatching Histone H3 Methyltransferase Activity
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