ZNF526 and SEPHS1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZNF526	SEPHS1
Description		zinc finger protein 526	selenophosphate synthetase 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Cytoplasm Plasma Membrane Membrane Nuclear Membrane
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Nucleotide Binding Selenide, Water Dikinase Activity Protein Binding ATP Binding GTP Binding Kinase Activity Transferase Activity Identical Protein Binding Protein Homodimerization Activity Metal Ion Binding Protein Heterodimerization Activity
	Biological Process		Selenocysteine Biosynthetic Process Protein Modification Process
Pathways
Drugs
Diseases
GWAS		Hodgkin's lymphoma ( 34216518) Meat-related diet ( 32066663)	Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Metabolite levels ( 23823483) Schizophrenia x sex interaction ( 34099189)
Interacting Genes		54 interacting genes: ATXN7L2 BAHD1 C8orf33 FAM161A FAM90A1 FARS2 GPATCH2L GRAP2 HNRNPK IL16 INO80B IQUB KAT5 LMO1 LMO3 MAPRE3 MRPL11 NCK2 NME7 OVOL2 PADI6 PBK PHF1 PIN1 PRKAB2 PRPF18 RBM10 SCNM1 SEPHS1 SPANXN2 SYCE1L TCEA2 THAP1 THAP12 TRIM41 U2AF2 VCX2 YJU2 ZBTB24 ZFP91 ZNF124 ZNF264 ZNF408 ZNF438 ZNF497 ZNF524 ZNF575 ZNF578 ZNF696 ZNF76 ZNF774 ZNF792 ZNF835 ZNF837	18 interacting genes: CDCA4 CRMP1 DEPDC7 ERG28 GBP2 IGSF21 PLAGL2 QRICH1 SAT1 SLC35F6 SPACA9 UNC119 XAF1 ZBTB25 ZNF202 ZNF276 ZNF474 ZNF526
Entrez ID		116115	22929
HPRD ID		15818	02944
Ensembl ID		ENSG00000167625	ENSG00000086475
Uniprot IDs		H9ZYJ3 Q8TF50	P49903
PDB IDs			3FD5 3FD6
Enriched GO Terms of Interacting Partners?		Zinc Ion Binding Nucleus Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process Metal Ion Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Spliceosomal Complex MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing
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