GRAP2 and TSNAXIP1

Number of citations of the paper that reports this interaction (PubMedID 27107012)
72

Data Source:
BioGRID (two hybrid)

		GRAP2	TSNAXIP1
Description		GRB2 related adaptor protein 2	translin associated factor X interacting protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Endosome Cytosol Plasma Membrane	Cytoplasm Perinuclear Region Of Cytoplasm
	Molecular Function	Phosphotyrosine Residue Binding Protein Binding	Protein Binding
	Biological Process	Signal Transduction Ras Protein Signal Transduction Cell-cell Signaling Regulation Of MAPK Cascade	Spermatogenesis Cell Differentiation
Pathways		Signaling by SCF-KIT Generation of second messenger molecules DAP12 signaling FCERI mediated MAPK activation FCERI mediated Ca+2 mobilization FCERI mediated Ca+2 mobilization Co-stimulation by CD28 FLT3 Signaling Signaling by CSF1 (M-CSF) in myeloid cells
Drugs
Diseases
GWAS		Body mass index ( 26426971) Systemic lupus erythematosus ( 28714469)	A body shape index ( 34021172) Empathy quotient ( 29527006) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		78 interacting genes: AR BAG4 BEND5 BLNK CBL CBLB CBY2 CCHCR1 CCNDBP1 CD28 COG6 CSF1R DNM2 DVL2 EGFR ERBB2 ERBB3 ERBB4 ETV5 FASLG GAB1 GAB2 GAB3 GAREM1 GATA1 GFAP GOLGA2 GRB2 HNRNPK IHO1 IKZF3 KHDRBS1 KHDRBS2 KIT KPRP KRT13 KRTAP1-3 KRTAP4-11 KRTAP4-12 LAT LATS2 LAX1 LCP2 LNX1 LNX2 MAGED1 MAP4K1 MKRN3 MOS MTUS2 PBLD PNMA1 PRKAA2 PRPH2 PRR35 RACK1 RAVER1 RBPMS RIN3 RINT1 SH2D4A SHB SHC1 SOS2 SPRY2 SSX2IP STAMBP TFIP11 TLE5 TRAF1 TSNAXIP1 USP8 WWP2 YWHAE ZBTB7B ZNF250 ZNF319 ZNF526	12 interacting genes: APP CDC7 FAM161B GRAP2 HSPB1 PRPF18 PRPF6 ROPN1 SNW1 SPG21 TSNAX UTP6
Entrez ID		9402	55815
HPRD ID		05156	09656
Ensembl ID		ENSG00000100351	ENSG00000102904
Uniprot IDs		B7Z8E3 B7Z8F8 O75791 Q6FI14	B4DXD0 E7ENJ7 Q2TAA8
PDB IDs		5GJH
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Intracellular Signal Transduction Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Cell Surface Receptor Signaling Pathway Regulation Of Programmed Cell Death Regulation Of Intracellular Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Apoptotic Process Regulation Of Signal Transduction Positive Regulation Of Signal Transduction ERBB Signaling Pathway Positive Regulation Of Cell Communication Positive Regulation Of Signaling Signaling Adaptor Activity Enzyme-linked Receptor Protein Signaling Pathway Regulation Of Cell Communication Regulation Of Signaling Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Intracellular Signal Transduction Positive Regulation Of MAPK Cascade SH2 Domain Binding Antigen Receptor-mediated Signaling Pathway Regulation Of MAPK Cascade Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Immune Response-regulating Cell Surface Receptor Signaling Pathway Protein Binding Positive Regulation Of Protein Modification Process Identical Protein Binding Immune Response-activating Cell Surface Receptor Signaling Pathway Response To Growth Factor Signal Transduction Negative Regulation Of Programmed Cell Death Cellular Response To Growth Factor Stimulus Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity Positive Regulation Of Protein Metabolic Process Regulation Of Cell Population Proliferation Positive Regulation Of Protein Phosphorylation Regulation Of Protein Modification Process Lymphocyte Activation Intracellular Signaling Cassette Negative Regulation Of Apoptotic Process Leukocyte Activation Positive Regulation Of Phosphate Metabolic Process Phosphotyrosine Residue Binding Positive Regulation Of Phosphorylation Cellular Response To Epidermal Growth Factor Stimulus Immune Response-regulating Signaling Pathway ERBB2 Signaling Pathway Positive Regulation Of Cell Population Proliferation Transmembrane Receptor Protein Tyrosine Kinase Activity Response To Epidermal Growth Factor	Collateral Sprouting Neuron Maturation Cell Maturation RNA Processing Spliceosomal Complex U5 SnRNP Developmental Maturation U4/U6 X U5 Tri-snRNP Complex Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Negative Regulation Of Protein Kinase C Signaling U2-type Post-spliceosomal Complex Positive Regulation Of Interleukin-1 Beta Production Acetylcholine Receptor Activator Activity PTB Domain Binding Positive Regulation Of Interleukin-1 Production Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Axo-dendritic Transport Response To Growth Factor Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Nucleus Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Regulation Of Interleukin-1 Beta Production Protein Kinase C Inhibitor Activity A2A Adenosine Receptor Binding Generation Of Catalytic Spliceosome For Second Transesterification Step RNA Splicing Catalytic Step 2 Spliceosome Microtubule-based Movement Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Interleukin-1 Production Axon Midline Choice Point Recognition Positive Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Developmental Cell Growth
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?