ZNF526 and THAP12

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		ZNF526	THAP12
Description		zinc finger protein 526	THAP domain containing 12
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding Protein Dimerization Activity
	Biological Process		Signal Transduction Negative Regulation Of Cell Population Proliferation
Pathways
Drugs
Diseases
GWAS		Hodgkin's lymphoma ( 34216518) Meat-related diet ( 32066663)	Asthma ( 31959851) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction ( 34099189)
Interacting Genes		54 interacting genes: ATXN7L2 BAHD1 C8orf33 FAM161A FAM90A1 FARS2 GPATCH2L GRAP2 HNRNPK IL16 INO80B IQUB KAT5 LMO1 LMO3 MAPRE3 MRPL11 NCK2 NME7 OVOL2 PADI6 PBK PHF1 PIN1 PRKAB2 PRPF18 RBM10 SCNM1 SEPHS1 SPANXN2 SYCE1L TCEA2 THAP1 THAP12 TRIM41 U2AF2 VCX2 YJU2 ZBTB24 ZFP91 ZNF124 ZNF264 ZNF408 ZNF438 ZNF497 ZNF524 ZNF575 ZNF578 ZNF696 ZNF76 ZNF774 ZNF792 ZNF835 ZNF837	10 interacting genes: DNAJC3 EIF2AK2 EIF2S1 KIAA1958 MAPKAPK3 RIGI STK4 TACC1 TP53 ZNF526
Entrez ID		116115	5612
HPRD ID		15818	09567
Ensembl ID		ENSG00000167625	ENSG00000137492
Uniprot IDs		H9ZYJ3 Q8TF50	A0A140VJQ7 O43422
PDB IDs
Enriched GO Terms of Interacting Partners?		Zinc Ion Binding Nucleus Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process Metal Ion Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Spliceosomal Complex MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing	Regulation Of Translation In Response To Endoplasmic Reticulum Stress Response To Endoplasmic Reticulum Stress Regulation Of Translational Initiation In Response To Stress Regulation Of Translational Initiation Positive Regulation Of Epithelial Cell Apoptotic Process Regulation Of Translation In Response To Stress Regulation Of Protein Metabolic Process Cellular Response To Starvation Negative Regulation Of Translation Intracellular Signal Transduction ER-nucleus Signaling Pathway Response To Starvation Negative Regulation Of Protein Metabolic Process Mitophagy Cellular Response To Amino Acid Starvation Regulation Of Epithelial Cell Apoptotic Process Translation Initiation Ternary Complex Cellular Response To Nutrient Levels Defense Response To Virus Positive Regulation Of Translation Initiation In Response To Endoplasmic Reticulum Stress Negative Regulation Of Endoplasmic Reticulum Stress-induced EIF2 Alpha Phosphorylation Positive Regulation Of Hepatocyte Apoptotic Process Negative Regulation Of Helicase Activity Negative Regulation Of G1 To G0 Transition MRNA Transcription Response To Amino Acid Starvation Endoplasmic Reticulum Unfolded Protein Response Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Autophagy Of Mitochondrion Double-stranded RNA Binding Translational Initiation Antiviral Innate Immune Response Protein Serine Kinase Activity Response To Manganese-induced Endoplasmic Reticulum Stress Glial Limiting End-foot Cellular Response To UV Cellular Response To Light Stimulus Regulation Of Translation Response To Virus Regulation Of Stem Cell Proliferation Protein Serine/threonine Kinase Activity Positive Regulation Of Translational Initiation In Response To Stress Protein-folding Chaperone Binding Negative Regulation Of Translation In Response To Endoplasmic Reticulum Stress Positive Regulation Of Substrate-dependent Cell Migration, Cell Attachment To Substrate Protein Tetramerization Oligodendrocyte Apoptotic Process Negative Regulation Of Fermentation Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia
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