PRKRIR and TACC1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PRKRIR	TACC1
Gene Name		protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)	transforming, acidic coiled-coil containing protein 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Cytoplasm Microtubule Organizing Center Microtubule Cytoskeleton Intermediate Filament Cytoskeleton
	Molecular Function	DNA Binding Metal Ion Binding Protein Dimerization Activity	Protein Binding Protein Domain Specific Binding
	Biological Process	Response To Stress Signal Transduction Negative Regulation Of Cell Proliferation	Microtubule Cytoskeleton Organization Cell Cycle Cell Proliferation Cerebral Cortex Development Neurogenesis Interkinetic Nuclear Migration Regulation Of Microtubule-based Process Cell Division
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: DDX58 DNAJC3 EIF2AK2 EIF2S1 STK4 TACC1 TP53	16 interactors: AURKA AURKB BTRC CKAP5 HTT ITSN2 KAT2A KDM1A LSM7 MEMO1 PRKRIR SH2D4A SNRPG STX5 TDRD7 YEATS4
Entrez ID		5612	6867
HPRD ID		09567	10391
Ensembl ID		ENSG00000137492	ENSG00000147526
Uniprot IDs		O43422	G8JLK4 O75410 Q5HYH0
PDB IDs
Enriched GO Terms of Interacting Partners?		ER-nucleus Signaling Pathway Response To Endoplasmic Reticulum Stress Positive Regulation Of Protein Phosphorylation Positive Regulation Of Phosphorylation Positive Regulation Of Protein Modification Process Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Unfolded Protein Regulation Of Translational Initiation In Response To Stress Cellular Response To Topologically Incorrect Protein Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Kinase Activity Response To Unfolded Protein Positive Regulation Of Kinase Activity Positive Regulation Of Protein Metabolic Process Regulation Of Translation In Response To Stress Regulation Of Phosphorylation Positive Regulation Of Transferase Activity Defense Response To Virus Positive Regulation Of Cellular Metabolic Process Regulation Of Phosphorus Metabolic Process Protein Autophosphorylation Regulation Of Protein Kinase Activity Response To Biotic Stimulus Regulation Of Kinase Activity Response To Virus Positive Regulation Of Metabolic Process Regulation Of Cellular Protein Metabolic Process Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Positive Regulation Of Nuclease Activity Immune System Process Regulation Of Protein Metabolic Process Regulation Of Catalytic Activity Regulation Of Translational Initiation Response To Organic Substance Regulation Of Defense Response To Virus Evasion Or Tolerance By Virus Of Host Immune Response Viral Process Regulation Of Apoptotic Process Regulation Of Stem Cell Proliferation Cellular Response To Stress Positive Regulation Of Catalytic Activity Regulation Of Cell Death Negative Regulation Of Macromitophagy Regulation Of Hematopoietic Stem Cell Differentiation Oligodendrocyte Apoptotic Process Signal Transduction Negative Regulation Of Cell Proliferation Negative Regulation Of Helicase Activity RIG-I Signaling Pathway	Spindle Stabilization Mitotic Cell Cycle Process Histone Modification Mitotic Cell Cycle Negative Regulation Of Protein Binding Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Histone-serine Phosphorylation Chromatin Modification Cell Cycle Process Negative Regulation Of Binding Mitotic Nuclear Division G2/M Transition Of Mitotic Cell Cycle Chromatin Organization Spindle Organization Regulation Of Protein Stability Regulation Of Protein Binding Cell Cycle Microtubule Cytoskeleton Organization Regulation Of Microtubule-based Process Posttranscriptional Regulation Of Gene Expression Histone Phosphorylation Negative Regulation Of Microtubule Depolymerization Mitotic Spindle Organization Positive Regulation Of Protein Catabolic Process Chromosome Organization Organelle Organization Negative Regulation Of Microtubule Polymerization Or Depolymerization Histone H4 Acetylation Anterior/posterior Pattern Specification Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Cytokinesis Proteasomal Protein Catabolic Process Regulation Of Binding Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Neural Plate Formation Regulation Of Primitive Erythrocyte Differentiation Negative Regulation Of Spindle Checkpoint Positive Regulation Of Metabolic Process Positive Regulation Of Cell Cycle Regulation Of Microtubule Polymerization Or Depolymerization Cell Proliferation Golgi Organization Spindle Assembly Spindle Assembly Involved In Female Meiosis I Serotonin Uptake Lactate Biosynthetic Process From Pyruvate Microtubule-based Process Diencephalon Development Centrosome Organization
Tagcloud ?			acidic additionally amplification clinicopathological coil coiled correlation cytoplasmic dysregulation fda fish gc her2 immunohistochemistry indicator lymph maybe node occurs positive prognostic resected stage synergistic thought tnm transforming unclear valuable
Tagcloud (Difference) ?			acidic additionally amplification clinicopathological coil coiled correlation cytoplasmic dysregulation fda fish gc her2 immunohistochemistry indicator lymph maybe node occurs positive prognostic resected stage synergistic thought tnm transforming unclear valuable
Tagcloud (Intersection) ?