PRKRIR

Gene Name		protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus
	Molecular Function	DNA Binding Metal Ion Binding Protein Dimerization Activity
	Biological Process	Response To Stress Signal Transduction Negative Regulation Of Cell Proliferation
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		7 interactors: DDX58 DNAJC3 EIF2AK2 EIF2S1 STK4 TACC1 TP53
Entrez ID		5612
HPRD ID		09567
Ensembl ID		ENSG00000137492
Uniprot IDs		O43422
PDB IDs
Enriched GO Terms of Interacting Partners?		ER-nucleus Signaling Pathway Response To Endoplasmic Reticulum Stress Positive Regulation Of Protein Phosphorylation Positive Regulation Of Phosphorylation Positive Regulation Of Protein Modification Process Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Unfolded Protein Regulation Of Translational Initiation In Response To Stress Cellular Response To Topologically Incorrect Protein Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Kinase Activity Response To Unfolded Protein Positive Regulation Of Kinase Activity Positive Regulation Of Protein Metabolic Process Regulation Of Translation In Response To Stress Regulation Of Phosphorylation Positive Regulation Of Transferase Activity Defense Response To Virus Positive Regulation Of Cellular Metabolic Process Regulation Of Phosphorus Metabolic Process Protein Autophosphorylation Regulation Of Protein Kinase Activity Response To Biotic Stimulus Regulation Of Kinase Activity Response To Virus Positive Regulation Of Metabolic Process Regulation Of Cellular Protein Metabolic Process Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Positive Regulation Of Nuclease Activity Immune System Process Regulation Of Protein Metabolic Process Regulation Of Catalytic Activity Regulation Of Translational Initiation Response To Organic Substance Regulation Of Defense Response To Virus Evasion Or Tolerance By Virus Of Host Immune Response Viral Process Regulation Of Apoptotic Process Regulation Of Stem Cell Proliferation Cellular Response To Stress Positive Regulation Of Catalytic Activity Regulation Of Cell Death Negative Regulation Of Macromitophagy Regulation Of Hematopoietic Stem Cell Differentiation Oligodendrocyte Apoptotic Process Signal Transduction Negative Regulation Of Cell Proliferation Negative Regulation Of Helicase Activity RIG-I Signaling Pathway
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