THAP12 and KIAA1958

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		THAP12	KIAA1958
Description		THAP domain containing 12	KIAA1958
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding Protein Dimerization Activity	Protein Binding
	Biological Process	Signal Transduction Negative Regulation Of Cell Population Proliferation
Pathways
Drugs
Diseases
GWAS		Asthma ( 31959851) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction ( 34099189)	Caudate nucleus volume ( 31530798) Cobalt levels ( 26025379) Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy) ( 25065397) Self-reported childhood asthma in adult smokers ( 30373671)
Interacting Genes		10 interacting genes: DNAJC3 EIF2AK2 EIF2S1 KIAA1958 MAPKAPK3 RIGI STK4 TACC1 TP53 ZNF526	13 interacting genes: AQP1 CEP19 COASY FAM124B GABARAPL2 LMO4 MCRS1 RWDD2B SOCS3 STAC TCEA2 TCEANC THAP12
Entrez ID		5612	158405
HPRD ID		09567	11173
Ensembl ID		ENSG00000137492	ENSG00000165185
Uniprot IDs		A0A140VJQ7 O43422	Q8N8K9
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Translation In Response To Endoplasmic Reticulum Stress Response To Endoplasmic Reticulum Stress Regulation Of Translational Initiation In Response To Stress Regulation Of Translational Initiation Positive Regulation Of Epithelial Cell Apoptotic Process Regulation Of Translation In Response To Stress Regulation Of Protein Metabolic Process Cellular Response To Starvation Negative Regulation Of Translation Intracellular Signal Transduction ER-nucleus Signaling Pathway Response To Starvation Negative Regulation Of Protein Metabolic Process Mitophagy Cellular Response To Amino Acid Starvation Regulation Of Epithelial Cell Apoptotic Process Translation Initiation Ternary Complex Cellular Response To Nutrient Levels Defense Response To Virus Positive Regulation Of Translation Initiation In Response To Endoplasmic Reticulum Stress Negative Regulation Of Endoplasmic Reticulum Stress-induced EIF2 Alpha Phosphorylation Positive Regulation Of Hepatocyte Apoptotic Process Negative Regulation Of Helicase Activity Negative Regulation Of G1 To G0 Transition MRNA Transcription Response To Amino Acid Starvation Endoplasmic Reticulum Unfolded Protein Response Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Autophagy Of Mitochondrion Double-stranded RNA Binding Translational Initiation Antiviral Innate Immune Response Protein Serine Kinase Activity Response To Manganese-induced Endoplasmic Reticulum Stress Glial Limiting End-foot Cellular Response To UV Cellular Response To Light Stimulus Regulation Of Translation Response To Virus Regulation Of Stem Cell Proliferation Protein Serine/threonine Kinase Activity Positive Regulation Of Translational Initiation In Response To Stress Protein-folding Chaperone Binding Negative Regulation Of Translation In Response To Endoplasmic Reticulum Stress Positive Regulation Of Substrate-dependent Cell Migration, Cell Attachment To Substrate Protein Tetramerization Oligodendrocyte Apoptotic Process Negative Regulation Of Fermentation Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia
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