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UBE2K and MARCH7
Number of citations of the paper that reports this interaction (PMID
16868077
)
12
Data Source:
BioGRID
(pull down)
UBE2K
MARCH7
Gene Name
ubiquitin-conjugating enzyme E2K
membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Actin Cytoskeleton
Intermediate Filament Cytoskeleton
Extracellular Vesicular Exosome
Molecular Function
Ubiquitin-protein Transferase Activity
Protein Binding
ATP Binding
Ligase Activity
Ubiquitin-like Protein Transferase Activity
Ubiquitin Protein Ligase Binding
Ubiquitin-ubiquitin Ligase Activity
Ubiquitin Protein Ligase Activity
Zinc Ion Binding
Ligase Activity
Biological Process
Ubiquitin-dependent Protein Catabolic Process
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
Protein K48-linked Ubiquitination
Protein Ubiquitination
Pathways
RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
Antigen processing: Ubiquitination & Proteasome degradation
Negative regulators of RIG-I/MDA5 signaling
Class I MHC mediated antigen processing & presentation
Innate Immune System
Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
68 interactors:
AMFR
ANAPC11
BFAR
BIRC7
BIRC8
BRCA1
CASP12
CBLC
CDC6
DDI1
DDX58
DIABLO
DTX3
DTX3L
DZIP3
FZR1
HTT
ITCH
ITSN1
LRSAM1
MARCH3
MARCH7
MDM2
MID1
MIPOL1
MKRN2
MKRN3
NEDD4L
NEDD8
NFKB1
NUB1
PIAS4
PRPF40A
PRRG4
RBCK1
REL
RING1
RNF111
RNF114
RNF125
RNF138
RNF144A
RNF167
RNF2
RNF32
RNF4
RNF41
RNF5
SIAH1
TP53
TRAF7
TRAIP
TRIM2
TRIM27
TRIM3
TRIM31
TRIM34
TRIM35
TRIM39
TRIM43
TRIM5
UBA1
UBC
UBE2I
UBOX5
UHRF2
WWP2
ZDHHC17
15 interactors:
MAPT
PPP3CA
PPP3CB
RNF111
TRIM65
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2E1
UBE2K
UBE2M
UBE2N
USP7
VAV2
Entrez ID
3093
64844
HPRD ID
04165
09817
Ensembl ID
ENSG00000078140
Uniprot IDs
B4DIZ2
P61086
Q9H992
PDB IDs
1YLA
2O25
3E46
3F92
3K9O
3K9P
Enriched GO Terms of Interacting Partners
?
Protein Modification By Small Protein Conjugation
Protein Ubiquitination
Cellular Protein Modification Process
Protein Polyubiquitination
Cellular Protein Metabolic Process
Protein Metabolic Process
Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Ubiquitin-dependent Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Cellular Metabolic Process
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Proteolysis
Proteasomal Protein Catabolic Process
Apoptotic Process
Programmed Cell Death
Cell Death
Death
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of Cell Death
Protein K63-linked Ubiquitination
Negative Regulation Of Cellular Metabolic Process
Metabolic Process
Regulation Of Apoptotic Process
Catabolic Process
Protein Autoubiquitination
Positive Regulation Of Signal Transduction
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Innate Immune Response
Regulation Of Signal Transduction
Regulation Of Protein Metabolic Process
Positive Regulation Of Intracellular Signal Transduction
Negative Regulation Of RNA Biosynthetic Process
Viral Process
Neuron Apoptotic Process
Response To Stress
Negative Regulation Of Biosynthetic Process
Regulation Of Viral Release From Host Cell
Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Protein Metabolic Process
Regulation Of Cell Cycle Process
Neuron Death
Regulation Of Signaling
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Transcription, DNA-templated
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Cell Cycle
Protein Polyubiquitination
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Protein Catabolic Process
Protein K48-linked Ubiquitination
Immune Response-regulating Signaling Pathway
Cellular Macromolecule Catabolic Process
Toll-like Receptor 4 Signaling Pathway
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Cellular Protein Modification Process
Toll-like Receptor Signaling Pathway
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Innate Immune Response
Proteasomal Protein Catabolic Process
Regulation Of Immune Response
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Positive Regulation Of Protein Ubiquitination
Activation Of Innate Immune Response
Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Regulation Of DNA-templated Transcription In Response To Stress
Proteolysis
TRIF-dependent Toll-like Receptor Signaling Pathway
Positive Regulation Of Innate Immune Response
Cellular Response To Transforming Growth Factor Beta Stimulus
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Response To Transforming Growth Factor Beta
Positive Regulation Of Ubiquitin-protein Transferase Activity
Regulation Of Protein Ubiquitination
Cellular Protein Metabolic Process
Positive Regulation Of Ligase Activity
Catabolic Process
Response To Organic Substance
Fc-epsilon Receptor Signaling Pathway
Cellular Response To Organic Substance
Immune Response
Regulation Of Ubiquitin-protein Transferase Activity
Regulation Of Immune System Process
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Regulation Of Innate Immune Response
Defense Response
Cellular Response To Hypoxia
Cellular Response To Decreased Oxygen Levels
Fc Receptor Signaling Pathway
Tagcloud
?
antiviral
attributes
breadth
chains
conjugase
cooperated
demands
e3
elicits
elusive
epsilon
hundreds
identifies
ifn
ikkepsilon
interacted
interferons
isg
isgs
k48
ligase
polyubiquitin
stat1
trim
trim6
tripartite
ubiquitin
unanchored
unrecognized
Tagcloud (Difference)
?
antiviral
attributes
breadth
chains
conjugase
cooperated
demands
e3
elicits
elusive
epsilon
hundreds
identifies
ifn
ikkepsilon
interacted
interferons
isg
isgs
k48
ligase
polyubiquitin
stat1
trim
trim6
tripartite
ubiquitin
unanchored
unrecognized
Tagcloud (Intersection)
?