SRSF6 and CRNDE

Number of citations of the paper that reports this interaction (PubMedID 33397371)
10

Data Source:
BioGRID (unspecified method, affinity chromatography technology)

		SRSF6	CRNDE
Description		serine and arginine rich splicing factor 6	colorectal neoplasia differentially expressed
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Speck
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding Pre-mRNA Binding
	Biological Process	RNA Splicing, Via Transesterification Reactions Alternative MRNA Splicing, Via Spliceosome Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splice Site Recognition MRNA Processing RNA Splicing Negative Regulation Of Gene Expression Regulation Of Keratinocyte Proliferation Response To Insulin Negative Regulation Of Keratinocyte Differentiation Negative Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Regulation Of Wound Healing Negative Regulation Of Type B Pancreatic Cell Apoptotic Process
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway mRNA 3'-end processing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Adult body size ( 32376654) Antibody level in response to infection ( 25758998) Daytime sleep phenotypes ( 27126917) HDL cholesterol levels in HIV infection ( 33109212)	Brugada syndrome ( 35210625) Carotid intima media thickness x smoking interaction ( 32117412) Intake of sweets ( 31005972) Thrombin-activatable fibrinolysis inhibitor activation peptide ( 29378355)
Interacting Genes		16 interacting genes: APP CLK1 CRNDE LUC7L LUC7L2 OGT PPARGC1A RBM10 RNPS1 SF3B4 SREK1 SRPK1 SRSF4 TERF1 TERF2 TOE1	2 interacting genes: HNRNPA2B1 SRSF6
Entrez ID		6431	643911
HPRD ID		09054
Ensembl ID		ENSG00000124193	ENSG00000245694
Uniprot IDs		Q13247
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Splicing Nuclear Speck MRNA Processing Regulation Of RNA Splicing RNA Processing Nucleic Acid Binding MRNA Metabolic Process Negative Regulation Of Telomeric D-loop Disassembly Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Negative Regulation Of MRNA Splicing, Via Spliceosome Nucleic Acid Metabolic Process Negative Regulation Of RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Shelterin Complex RNA Metabolic Process Nucleoplasm Nucleobase-containing Compound Metabolic Process Telomerase Activity RNA Binding Protein-RNA Complex Assembly Nuclear Telomere Cap Complex Telomeric D-loop Disassembly Double-stranded Telomeric DNA Binding RNA Splicing, Via Transesterification Reactions G-rich Strand Telomeric DNA Binding Telomeric Loop Disassembly Nucleus Telomere Capping Protein-containing Complex Assembly Negative Regulation Of MRNA Metabolic Process U2-type Prespliceosome Macromolecule Metabolic Process U1 SnRNP Protein-containing Complex Organization Negative Regulation Of Telomere Maintenance Via Telomerase Regulation Of MRNA Metabolic Process RNA-templated DNA Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Telomeric DNA Binding Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Biosynthetic Process MRNA Splice Site Recognition Negative Regulation Of Telomere Maintenance Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Cellular Component Assembly Positive Regulation Of Toll Signaling Pathway	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome Single-stranded Telomeric DNA Binding DNA Geometric Change RNA Splicing Nucleic Acid Binding MRNA Metabolic Process MRNA Processing MiRNA Transport G-rich Strand Telomeric DNA Binding Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Negative Regulation Of Type B Pancreatic Cell Apoptotic Process Negative Regulation Of Keratinocyte Differentiation Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Primary MiRNA Processing N6-methyladenosine-containing RNA Reader Activity Negative Regulation Of Epidermal Cell Differentiation DNA Conformation Change Pre-mRNA Binding RNA Processing DNA Polymerase Binding Negative Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Epithelial Cell Apoptotic Process Negative Regulation Of RNA Splicing Alternative MRNA Splicing, Via Spliceosome MiRNA Processing MRNA Splice Site Recognition MiRNA Binding Regulation Of Keratinocyte Differentiation Regulation Of Keratinocyte Proliferation Molecular Condensate Scaffold Activity Negative Regulation Of Epithelial Cell Differentiation Regulation Of Telomere Maintenance Via Telomere Lengthening Regulation Of Epithelial Cell Apoptotic Process RNA Metabolic Process Regulation Of Epidermal Cell Differentiation Cajal Body MRNA Export From Nucleus RNA Binding Regulation Of Epidermis Development Regulation Of Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of Telomere Maintenance RNA Export From Nucleus Catalytic Step 2 Spliceosome Positive Regulation Of Chromosome Organization Negative Regulation Of MRNA Metabolic Process Regulation Of Telomere Maintenance Regulation Of MRNA Splicing, Via Spliceosome Nucleic Acid Metabolic Process
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