SAT2 and SAT1

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SAT2	SAT1
Gene Name		spermidine/spermine N1-acetyltransferase family member 2	spermidine/spermine N1-acetyltransferase 1
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Extracellular Vesicular Exosome	Intracellular Cytosol
	Molecular Function	Diamine N-acetyltransferase Activity	Diamine N-acetyltransferase Activity Protein Binding Spermidine Binding
	Biological Process	Putrescine Catabolic Process Spermidine Acetylation Spermine Acetylation Putrescine Acetylation Nor-spermidine Metabolic Process	Angiogenesis Polyamine Metabolic Process Polyamine Biosynthetic Process Putrescine Catabolic Process Spermidine Acetylation Cellular Nitrogen Compound Metabolic Process Regulation Of Cell Proliferation Small Molecule Metabolic Process
Pathways			Metabolism of polyamines Interconversion of polyamines Metabolism of amino acids and derivatives
Drugs			N-ethyl-N-[3-(propylamino)propyl]propane-1,3-diamine
Diseases
GWAS		Sex hormone-binding globulin levels ( 22675492)
Protein-Protein Interactions		5 interactors: KAT2B SAT1 TCEB1 TGFBR1 VHL	75 interactors: ABCB8 APLP1 B4GALT3 C14orf1 C19orf25 CASP7 CCDC148 CCDC90B CCHCR1 CHD3 COPS6 CRMP1 CSNK2A1 CSNK2A2 DDX39A DGKZ DMRT3 DNPEP EEF1G EIF3D EPHB6 EVA1A FAM156A FAM69B FAM86C1 FTSJ3 FUNDC2 GBP2 GDF9 GNB2L1 HIF1A HOXB6 HOXB9 HSPE1 INO80C ITGA9 JUNB KAT5 KAT7 KCNA4 KIAA1377 LNX1 LRIF1 LUC7L2 MED31 MRPL9 MTA1 NIF3L1 NMRK2 PLGRKT PRDX2 PTN RBM17 RBM48 REL RELA RPLP1 SARAF SAT2 SEPHS1 SETDB1 SNAI2 TACO1 TCF25 TLE1 TP53 TP53TG1 TSC22D4 TUBB2A UBE2D3 UNC119 UTP14A VASP VKORC1 ZHX1
Entrez ID		112483	6303
HPRD ID		15296	02431
Ensembl ID		ENSG00000141504	ENSG00000130066
Uniprot IDs		I3L0W4 Q96F10	P21673 Q6ICU9
PDB IDs		2BEI 2Q4V	2B3U 2B3V 2B4B 2B4D 2B58 2B5G 2F5I 2FXF 2G3T 2JEV
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Positive Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Regulation Of Cell Proliferation Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Cellular Response To Oxygen Levels Negative Regulation Of Cell Proliferation Cell Cycle Arrest Histone H3-K9 Acetylation Regulation Of Protein ADP-ribosylation Spermidine Acetylation N-terminal Peptidyl-lysine Acetylation Putrescine Catabolic Process Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Oxalate Transport Polyamine Catabolic Process 3'-phosphoadenosine 5'-phosphosulfate Biosynthetic Process Positive Regulation Of Gluconeogenesis By Positive Regulation Of Transcription From RNA Polymerase II Promoter Response To Hypoxia Regulation Of Cellular Ketone Metabolic Process By Positive Regulation Of Transcription From RNA Polymerase II Promoter Parathyroid Gland Development Regulation Of Gluconeogenesis By Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Stimulus Angiogenesis Positive Regulation Of Metabolic Process Regulation Of Protein Glycosylation N-terminal Protein Amino Acid Acetylation Endothelial Cell Activation Neurotransmitter Uptake Pathway-restricted SMAD Protein Phosphorylation Positive Regulation Of SMAD Protein Import Into Nucleus Blood Vessel Morphogenesis 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Negative Regulation Of Cell Cycle Regulation Of SMAD Protein Import Into Nucleus Polyamine Biosynthetic Process Positive Regulation Of Gluconeogenesis Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter Germ Cell Migration Regulation Of Transcription From RNA Polymerase II Promoter Pharyngeal System Development Blood Vessel Development Response To Cholesterol Regulation Of Transcription, DNA-templated	RNA Metabolic Process Gene Expression RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Transcription, DNA-templated Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Macromolecule Biosynthetic Process Cellular Metabolic Process Biosynthetic Process Negative Regulation Of Biosynthetic Process Metabolic Process Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Protein Metabolic Process Response To Radiation Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nucleic Acid-templated Transcription Cellular Process Regulation Of RNA Biosynthetic Process Regulation Of Protein Metabolic Process Regulation Of RNA Metabolic Process Response To External Stimulus Negative Regulation Of Oxidative Stress-induced Neuron Death Regulation Of Metabolic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Interleukin-12 Biosynthetic Process Negative Regulation Of Gene Expression Chemotaxis Response To Light Stimulus DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Notch Signaling Pathway Transcription From RNA Polymerase II Promoter Osteoblast Differentiation Locomotion Regulation Of Interleukin-12 Biosynthetic Process DNA Damage Response, Signal Transduction Resulting In Transcription Response To Ionizing Radiation Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Mitotic Cell Cycle Phase Transition Axon Guidance Response To Abiotic Stimulus
Tagcloud ?		aada1 aeromonas altogether anthropogenic antimicrobials bacteria bearing cassette cassettes class dfra1 ecosystems environments harbouring hydrophila integron integrons klebsiella lactamase lakes living multocida park pasteurella pneumoniae poland preservation shv wielkopolski	acetyltransferase biologic catabolism chemoradiation databases dr dramatic explaining gbm glioblastoma ionizing lies mechanistically multiforme n1 neurosphere oncomine polyamine radiation radioresistance radiosensitization recombination referenced rembrandt sensitization sensitize shrna spermidine spermine
Tagcloud (Difference) ?		aada1 aeromonas altogether anthropogenic antimicrobials bacteria bearing cassette cassettes class dfra1 ecosystems environments harbouring hydrophila integron integrons klebsiella lactamase lakes living multocida park pasteurella pneumoniae poland preservation shv wielkopolski	acetyltransferase biologic catabolism chemoradiation databases dr dramatic explaining gbm glioblastoma ionizing lies mechanistically multiforme n1 neurosphere oncomine polyamine radiation radioresistance radiosensitization recombination referenced rembrandt sensitization sensitize shrna spermidine spermine
Tagcloud (Intersection) ?