SAT2

Description		spermidine/spermine N1-acetyltransferase family member 2
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GO Annotations	Cellular Component	Cytoplasm Extracellular Exosome
	Molecular Function	Diamine N-acetyltransferase Activity Protein Binding N-acetyltransferase Activity Transferase Activity Acyltransferase Activity Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups Identical Protein Binding
	Biological Process	Polyamine Biosynthetic Process Spermidine Acetylation Spermine Acetylation Putrescine Acetylation Nor-spermidine Metabolic Process
Pathways
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Serum metabolite levels ( 33031748) Sex hormone-binding globulin levels ( 22675492)
Interacting Genes		5 interacting genes: ELOC KAT2B SAT1 TGFBR1 VHL
Entrez ID		112483
HPRD ID		15296
Ensembl ID		ENSG00000141504
Uniprot IDs		I3L0W4 Q502X4 Q96F10
PDB IDs		2BEI 2Q4V
Enriched GO Terms of Interacting Partners?		Diamine N-acetyltransferase Activity Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups Spermidine Acetylation Putrescine Catabolic Process Regulation Of Cell Population Proliferation Spermidine Binding Protein Modification Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Vascular Endothelial Cell Proliferation Epicardium Morphogenesis Negative Regulation Of RRNA Processing Histone H3K9 Acetyltransferase Activity Polyamine Catabolic Process Acyltransferase Activity Catabolic Process Target-directed MiRNA Degradation Elongin Complex Negative Regulation Of Cell Population Proliferation Positive Regulation Of Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation Proepicardium Development Angiogenesis Involved In Coronary Vascular Morphogenesis Positive Regulation Of Tight Junction Disassembly Transforming Growth Factor Beta Ligand-receptor Complex DNA-binding Transcription Factor Binding N-terminal Peptidyl-lysine Acetylation Negative Regulation Of Ribosome Biogenesis Spermidine Metabolic Process Putrescine Metabolic Process Positive Regulation Of Biosynthetic Process Macromolecule Catabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Gene Expression Positive Regulation Of Mesenchymal Stem Cell Proliferation Myofibroblast Differentiation Activin Receptor Complex Activin Receptor Activity, Type I Ventricular Compact Myocardium Morphogenesis Coronary Artery Morphogenesis Parathyroid Gland Development Positive Regulation Of Cardiac Epithelial To Mesenchymal Transition Germ Cell Migration Transforming Growth Factor Beta Receptor Activity Trophoblast Cell Migration Heart Development Regulation Of Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation Negative Regulation Of Programmed Cell Death Transforming Growth Factor Beta Receptor Activity, Type I Transcription Elongation Factor Activity
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