TNFRSF10C and SYAP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TNFRSF10C	SYAP1
Description		TNF receptor superfamily member 10c	synapse associated protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Membrane Side Of Membrane	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Cytoplasmic Side Of Plasma Membrane Membrane Axon Dendrite Growth Cone Presynaptic Membrane Cell Projection Perikaryon Synapse Postsynaptic Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding TRAIL Binding	Protein Binding
	Biological Process	Apoptotic Process TRAIL-activated Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Process	Cell Differentiation Cellular Response To Insulin Stimulus Cellular Response To Platelet-derived Growth Factor Stimulus TORC2 Signaling Positive Regulation Of Fat Cell Differentiation Regulation Of Short-term Neuronal Synaptic Plasticity Cellular Response To Epidermal Growth Factor Stimulus Positive Regulation Of Protein Serine/threonine Kinase Activity Cellular Response To Insulin-like Growth Factor Stimulus
Pathways		TP53 Regulates Transcription of Death Receptors and Ligands
Drugs
Diseases
GWAS		Basophil count ( 32888494) Eosinophil count ( 27863252 32888494) Eosinophil percentage of white cells ( 27863252 32888494) Granulocyte count ( 27863252) Mean spheric corpuscular volume ( 32888494) Monocyte percentage of white cells ( 32888494) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252 32888494) Neutrophil percentage of granulocytes ( 27863252) Sum basophil neutrophil counts ( 27863252) Sum eosinophil basophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 32888494 27863252) White blood cell count (basophil) ( 27863252)
Interacting Genes		34 interacting genes: APOA1 AQP6 ARL13B ASZ1 CD79A COQ9 CREB3L1 CXCL14 CYB5R3 DNAJC1 ERGIC3 FAM209A GPR152 GPR37L1 KCNJ6 KCNK5 LMNA LRSAM1 MGST1 MRPS18B PDZK1IP1 RAP1A RFLNB SGTA SLC27A6 SLC30A4 SRPK1 SRPK2 STOM SYAP1 TMEM45B TMEM80 TNFSF10 ZHX1	7 interacting genes: ADIPOQ MIP OGT POT1 THRA TNFRSF10C ZFPL1
Entrez ID		8794	94056
HPRD ID		04681	06733
Ensembl ID		ENSG00000173535	ENSG00000169895
Uniprot IDs		O14798	Q96A49
PDB IDs			1X3A
Enriched GO Terms of Interacting Partners?			Positive Regulation Of Cold-induced Thermogenesis Regulation Of Cold-induced Thermogenesis Negative Regulation Of Cellular Component Organization Regulation Of Myeloid Cell Apoptotic Process Negative Regulation Of DNA Biosynthetic Process Regulation Of Lipid Metabolic Process Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Regulation Of Gluconeogenesis Negative Regulation Of Metanephric Mesenchymal Cell Migration Positive Regulation Of Renal Albumin Absorption Positive Regulation Of Metanephric Podocyte Development Positive Regulation Of Glycogen (starch) Synthase Activity Positive Regulation Of DNA Strand Elongation Positive Regulation Of Telomeric D-loop Disassembly G-rich Single-stranded DNA Binding Chromatin DNA Binding Regulation Of DNA Biosynthetic Process Negative Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly Regulation Of Programmed Cell Death Thyroid Hormone Receptor Signaling Pathway Female Courtship Behavior Macromolecule Biosynthetic Process Positive Regulation Of Thyroid Hormone Receptor Signaling Pathway Negative Regulation Of Protein-containing Complex Assembly Hormone-mediated Signaling Pathway Positive Regulation Of Female Receptivity Response To Monosaccharide Positive Regulation Of Lipid Metabolic Process Response To Glucose Response To Nutrient Regulation Of Glucose Metabolic Process Protein O-acetylglucosaminyltransferase Activity Circadian Rhythm Negative Regulation Of Platelet-derived Growth Factor Receptor-alpha Signaling Pathway Response To Linoleic Acid Detection Of Oxidative Stress Negative Regulation Of Protein Autophosphorylation Negative Regulation Of Receptor Binding Negative Regulation Of DNA Metabolic Process Positive Regulation Of CAMP-dependent Protein Kinase Activity Negative Regulation Of Cholesterol Import Regulation Of Glycogen (starch) Synthase Activity Positive Regulation Of Telomeric Loop Disassembly 8-hydroxy-2'-deoxyguanosine DNA Binding Telomeric G-quadruplex DNA Binding Telomeric D-loop Binding Telomere Assembly Negative Regulation Of Nucleobase-containing Compound Metabolic Process Thyroid Hormone Binding
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