TNFRSF10C and TNFSF10

Number of citations of the paper that reports this interaction (PMID 9325248)
74

Data Source:
HPRD (in vivo, in vitro)

		TNFRSF10C	TNFSF10
Gene Name		tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain	tumor necrosis factor (ligand) superfamily, member 10
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Plasma Membrane Anchored Component Of Membrane	Extracellular Region Extracellular Space Integral Component Of Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Transmembrane Signaling Receptor Activity TRAIL Binding	Receptor Binding Cytokine Activity Tumor Necrosis Factor Receptor Binding Protein Binding Metal Ion Binding
	Biological Process	Apoptotic Process Signal Transduction	Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Immune Response Signal Transduction Cell-cell Signaling Male Gonad Development Response To Insulin Positive Regulation Of Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Release Of Cytochrome C From Mitochondria Apoptotic Signaling Pathway Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways			Regulation by c-FLIP Death Receptor Signalling TRAIL signaling Dimerization of procaspase-8 Caspase-8 activation by cleavage Programmed Cell Death Extrinsic Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: APOA1 FAM101B LRSAM1 RAP1A SLC27A6 SRPK1 SRPK2 TNFSF10 ZHX1	9 interactors: ACP5 CASP3 RBM48 TNFRSF10A TNFRSF10B TNFRSF10C TNFRSF10D TNFRSF11B ZDHHC17
Entrez ID		8794	8743
HPRD ID		04681	04670
Ensembl ID		ENSG00000173535	ENSG00000121858
Uniprot IDs		O14798	P50591 Q6IBA9
PDB IDs			1D0G 1D2Q 1D4V 1DG6 1DU3
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Viral Genome Replication Negative Regulation Of Viral Genome Replication Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Viral Genome Replication Positive Regulation Of Viral Process Negative Regulation Of Transport Negative Regulation Of Viral Process Negative Regulation Of Cell Adhesion Molecule Production Nuclear Speck Organization Ubiquitin-dependent Endocytosis Regulation Of MRNA Processing Cell Differentiation Regulation Of RNA Splicing Negative Regulation Of Interleukin-1 Beta Secretion Developmental Process Nucleus Organization Negative Regulation Of Very-low-density Lipoprotein Particle Remodeling Cholesterol Import Negative Regulation Of Interleukin-1 Secretion Regulation Of Viral Process Negative Regulation Of Secretion By Cell Negative Regulation Of Secretion High-density Lipoprotein Particle Clearance Platelet Activation Protein Oxidation Positive Regulation Of Intracellular Signal Transduction Negative Regulation Of Heterotypic Cell-cell Adhesion Negative Regulation Of Cytokine Secretion Involved In Immune Response High-density Lipoprotein Particle Assembly Cell Development Positive Regulation Of Triglyceride Catabolic Process Positive Regulation Of Cholesterol Esterification Sperm Chromatin Condensation Viral Budding Regulation Of Intestinal Cholesterol Absorption Rap Protein Signal Transduction Phospholipid Homeostasis Peptidyl-methionine Modification Anatomical Structure Development Regulation Of Cellular Component Organization Regulation Of Cholesterol Esterification Peripheral Nervous System Axon Regeneration Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Vasculogenesis Phospholipid Efflux Nerve Growth Factor Signaling Pathway Regulation Of Cytokine Secretion Involved In Immune Response Lipid Transport Positive Regulation Of Fatty Acid Biosynthetic Process Positive Regulation Of Lipoprotein Lipase Activity	Apoptotic Process Programmed Cell Death Cell Death Death Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Extrinsic Apoptotic Signaling Pathway Zymogen Activation Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Positive Regulation Of Endopeptidase Activity Positive Regulation Of Peptidase Activity Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Activation Of NF-kappaB-inducing Kinase Activity Protein Processing Positive Regulation Of NIK/NF-kappaB Signaling NIK/NF-kappaB Signaling Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of Proteolysis Apoptotic Signaling Pathway Signal Transduction Response To Stimulus Regulation Of Endopeptidase Activity Cellular Response To Mechanical Stimulus Regulation Of Peptidase Activity Signaling Cell Communication Negative Regulation Of Odontogenesis Of Dentin-containing Tooth Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Negative Regulation Of Superoxide Anion Generation Positive Regulation Of Apoptotic Process Cellular Response To Stimulus Positive Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Positive Regulation Of Cell Death TRAIL-activated Apoptotic Signaling Pathway Regulation Of Cell Death Regulation Of Proteolysis Regulation Of Protein Kinase Activity Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Intrinsic Apoptotic Signaling Pathway Regulation Of Kinase Activity Response To External Stimulus Negative Regulation Of Odontogenesis Riboflavin Metabolic Process Regulation Of Extrinsic Apoptotic Signaling Pathway Positive Regulation Of Intracellular Signal Transduction Glial Cell Apoptotic Process
Tagcloud ?			adenovirus apobec3a ddx58 exact expand hiv ifi27 ifi44l ifit1 ifit2 ifit3 innate irf7 isg15 isg20 isgs mdms microarray monocyte mx1 mx2 reservoirs rig rsad2 select stat1 trail viperin vpr
Tagcloud (Difference) ?			adenovirus apobec3a ddx58 exact expand hiv ifi27 ifi44l ifit1 ifit2 ifit3 innate irf7 isg15 isg20 isgs mdms microarray monocyte mx1 mx2 reservoirs rig rsad2 select stat1 trail viperin vpr
Tagcloud (Intersection) ?