MOAP1 and TRIM68

Number of citations of the paper that reports this interaction (PubMedID 36724555)
0

Data Source:
BioGRID (pull down)

		MOAP1	TRIM68
Description		modulator of apoptosis 1	tripartite motif containing 68
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Outer Membrane Cytosol Membrane	Nucleus Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Transferase Activity Histone Acetyltransferase Binding Identical Protein Binding Metal Ion Binding Nuclear Androgen Receptor Binding Ubiquitin Protein Ligase Activity
	Biological Process	Autophagy Apoptotic Process Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Protein Insertion Into Mitochondrial Membrane Positive Regulation Of Release Of Cytochrome C From Mitochondria Apoptotic Signaling Pathway Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Autophagosome Assembly	Regulation Of Gene Expression Protein Ubiquitination Innate Immune Response Protein Autoubiquitination Regulation Of Androgen Receptor Signaling Pathway
Pathways			Interferon gamma signaling
Drugs
Diseases
GWAS		Body mass index ( 26426971) Endometriosis ( 23472165) Migraine ( 27182965)	Malaria ( 31844061) Mean corpuscular hemoglobin ( 28548082) Mean corpuscular hemoglobin concentration ( 28548082) Mean corpuscular volume ( 28548082) Red blood cell count ( 28548082) White blood cell count ( 28548082)
Interacting Genes		28 interacting genes: BAX BCL2 BCL2L1 CACNA1A CAMK2D CCDC85B DPPA2 FXR1 FZR1 HUNK LATS1 LCOR MAGEH1 MBIP MEOX2 PNMA5 PPP2R3C RASSF1 RUSC1 SQSTM1 THOC1 TNFRSF10A TNFRSF1A TRIM68 UBQLN2 UBQLN4 UBR5 ZMYND12	16 interacting genes: DISC1 HUNK INCA1 KRTAP13-2 KRTAP13-3 LNX1 LZTFL1 MOAP1 NUDT16L1 POLR2G REL TCF4 TEPSIN UBE2D3 UBE2U ZBTB42
Entrez ID		64112	55128
HPRD ID		17580	11507
Ensembl ID		ENSG00000165943	ENSG00000167333
Uniprot IDs		Q96BY2	Q6AZZ1
PDB IDs		7LGC
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death BH3 Domain Binding Nucleus Bcl-2 Family Protein Complex Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Extrinsic Apoptotic Signaling Pathway Identical Protein Binding Apoptotic Process Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Mitochondrial Membrane Potential Programmed Cell Death Involved In Cell Development Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Nitrogen Utilization Release Of Cytochrome C From Mitochondria Retinal Cell Programmed Cell Death Dendritic Cell Apoptotic Process Programmed Cell Death Cell Death B Cell Homeostasis Regulation Of Metabolic Process Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand DNA Damage Response Channel Activity Positive Regulation Of Apoptotic Process Involved In Morphogenesis Cytoplasm Intracellular Membraneless Organelle Epithelial Cell Apoptotic Process Intracellular Signal Transduction Ovarian Follicle Development Leukocyte Apoptotic Process Positive Regulation Of Apoptotic Process Involved In Development Positive Regulation Of Developmental Pigmentation Molecular Condensate Scaffold Activity Regulation Of Membrane Depolarization Protein Polyubiquitination Response To Gamma Radiation Negative Regulation Of Dendritic Cell Apoptotic Process Regulation Of Macromolecule Metabolic Process Regulation Of Mitochondrial Membrane Permeability Cellular Response To Stress Lymphocyte Homeostasis Regulation Of Cellular Localization Apoptotic Mitochondrial Changes Apoptotic Signaling Pathway B Cell Apoptotic Process Intrinsic Apoptotic Signaling Pathway Calcium Ion Transport Into Cytosol Regulation Of Membrane Permeability Regulation Of Developmental Pigmentation
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