MOAP1 and PNMA5

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		MOAP1	PNMA5
Description		modulator of apoptosis 1	PNMA family member 5
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Outer Membrane Cytosol Membrane	Nucleus
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding	Protein Binding Identical Protein Binding
	Biological Process	Autophagy Apoptotic Process Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Protein Insertion Into Mitochondrial Membrane Positive Regulation Of Release Of Cytochrome C From Mitochondria Apoptotic Signaling Pathway Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Autophagosome Assembly	Positive Regulation Of Apoptotic Process
Pathways
Drugs
Diseases
GWAS		Body mass index ( 26426971) Endometriosis ( 23472165) Migraine ( 27182965)
Interacting Genes		28 interacting genes: BAX BCL2 BCL2L1 CACNA1A CAMK2D CCDC85B DPPA2 FXR1 FZR1 HUNK LATS1 LCOR MAGEH1 MBIP MEOX2 PNMA5 PPP2R3C RASSF1 RUSC1 SQSTM1 THOC1 TNFRSF10A TNFRSF1A TRIM68 UBQLN2 UBQLN4 UBR5 ZMYND12	59 interacting genes: AP1M1 APPL1 ARPC4 CADPS CARD9 CCDC102B CCNC CDC23 CEP57L1 CETN2 CRACR2A CSTPP1 CTNNA3 DDX6 DRC4 DZIP1L EHHADH FOXH1 FSD2 GLIPR2 GOLGA6L9 GORASP2 GPRASP3 GRB2 GYS1 HOOK3 HSF2BP KIF9 KIFC3 KPNA2 LHX3 LNX1 MAGED1 MOAP1 MYO15B NTAQ1 PAX5 PNKP PNMA1 POLR3C PRKAA1 PSMA1 RAD23B SH3KBP1 SORBS3 SPG21 TBC1D22B TCEA2 TCEANC TNPO2 TTC23 TXNL4B UBASH3A VIM VPS28 ZBTB25 ZFYVE26 ZMYND19 ZRANB1
Entrez ID		64112	114824
HPRD ID		17580	06678
Ensembl ID		ENSG00000165943	ENSG00000198883
Uniprot IDs		Q96BY2	Q96PV4
PDB IDs		7LGC
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death BH3 Domain Binding Nucleus Bcl-2 Family Protein Complex Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Extrinsic Apoptotic Signaling Pathway Identical Protein Binding Apoptotic Process Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Mitochondrial Membrane Potential Programmed Cell Death Involved In Cell Development Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Nitrogen Utilization Release Of Cytochrome C From Mitochondria Retinal Cell Programmed Cell Death Dendritic Cell Apoptotic Process Programmed Cell Death Cell Death B Cell Homeostasis Regulation Of Metabolic Process Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand DNA Damage Response Channel Activity Positive Regulation Of Apoptotic Process Involved In Morphogenesis Cytoplasm Intracellular Membraneless Organelle Epithelial Cell Apoptotic Process Intracellular Signal Transduction Ovarian Follicle Development Leukocyte Apoptotic Process Positive Regulation Of Apoptotic Process Involved In Development Positive Regulation Of Developmental Pigmentation Molecular Condensate Scaffold Activity Regulation Of Membrane Depolarization Protein Polyubiquitination Response To Gamma Radiation Negative Regulation Of Dendritic Cell Apoptotic Process Regulation Of Macromolecule Metabolic Process Regulation Of Mitochondrial Membrane Permeability Cellular Response To Stress Lymphocyte Homeostasis Regulation Of Cellular Localization Apoptotic Mitochondrial Changes Apoptotic Signaling Pathway B Cell Apoptotic Process Intrinsic Apoptotic Signaling Pathway Calcium Ion Transport Into Cytosol Regulation Of Membrane Permeability Regulation Of Developmental Pigmentation	XPC Complex Cytoskeleton Protein Binding Cytoplasm
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