MOAP1 and DPPA2

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		MOAP1	DPPA2
Gene Name		modulator of apoptosis 1	developmental pluripotency associated 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Outer Membrane Cytosol	Nucleus Nucleoplasm
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding	Chromatin Binding
	Biological Process	Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Apoptotic Process Positive Regulation Of Release Of Cytochrome C From Mitochondria Apoptotic Signaling Pathway Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Stem Cell Maintenance Regulation Of Histone Methylation Lung-associated Mesenchyme Development Positive Regulation Of Stem Cell Proliferation
Pathways
Drugs
Diseases
GWAS		Endometriosis ( 23472165)	Corneal astigmatism ( 23761726)
Protein-Protein Interactions		18 interactors: BAX BCL2 BCL2L1 CACNA1A CAMK2D CCDC85B DPPA2 FZR1 LATS1 MAGEH1 MBIP PNMA5 RASSF1 THOC1 TNFRSF10A TNFRSF1A UBC UBQLN4	16 interactors: AP2M1 DPPA4 DVL2 DVL3 FXR2 MCM10 MOAP1 PBXIP1 PLOD3 SDCBP2 SETD5 SPOP U2AF2 VTA1 ZCCHC10 ZNF250
Entrez ID		64112	151871
HPRD ID		17580	13248
Ensembl ID		ENSG00000165943	ENSG00000163530
Uniprot IDs		Q96BY2	Q7Z7J5
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Cell Cycle Extrinsic Apoptotic Signaling Pathway Cell Death Death Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Cellular Response To DNA Damage Stimulus Positive Regulation Of Apoptotic Process Apoptotic Signaling Pathway Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Apoptotic Process Programmed Cell Death Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Cellular Response To Stress Negative Regulation Of Cellular Metabolic Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Cell Cycle Regulation Of Neuron Apoptotic Process Regulation Of Metabolic Process Regulation Of Cell Cycle Process Release Of Cytochrome C From Mitochondria Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Protein Metabolic Process Regulation Of Nitrogen Utilization Regulation Of Neuron Death Regulation Of Mitochondrial Membrane Potential Regulation Of Phosphorylation Regulation Of Mitochondrial Membrane Permeability Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Protein Modification Process Regulation Of Organelle Organization Regulation Of Membrane Permeability Intracellular Signal Transduction Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Cellular Component Organization Positive Regulation Of Cellular Metabolic Process Regulation Of Apoptotic Process Regulation Of Phosphorus Metabolic Process Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Response To Gamma Radiation Regulation Of Protein Phosphorylation Regulation Of Cell Death Negative Regulation Of Neuron Apoptotic Process Response To Abiotic Stimulus Neuron Apoptotic Process Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Intrinsic Apoptotic Signaling Pathway	Planar Cell Polarity Pathway Involved In Neural Tube Closure Regulation Of Establishment Of Planar Polarity Involved In Neural Tube Closure Wnt Signaling Pathway, Planar Cell Polarity Pathway Cochlea Morphogenesis Non-canonical Wnt Signaling Pathway Cochlea Development Outflow Tract Morphogenesis Positive Regulation Of JUN Kinase Activity Regulation Of JUN Kinase Activity Intracellular Transport Canonical Wnt Signaling Pathway Cellular Localization Inner Ear Morphogenesis Convergent Extension Involved In Neural Plate Elongation Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Type B Pancreatic Cell Apoptotic Process Regulation Of Embryonic Development Protein Insertion Into Mitochondrial Membrane Basement Membrane Assembly Positive Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of JNK Cascade Ear Morphogenesis Positive Regulation Of Stress-activated MAPK Cascade Non-canonical Wnt Signaling Pathway Via JNK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Non-canonical Wnt Signaling Pathway Via MAPK Cascade Convergent Extension Involved In Organogenesis Positive Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Canonical Wnt Signaling Pathway Protein Localization Positive Regulation Of Wnt Signaling Pathway Regulation Of JNK Cascade Establishment Of Localization In Cell Positive Regulation Of Signal Transduction Canonical Wnt Signaling Pathway Involved In Regulation Of Cell Proliferation Neural Plate Morphogenesis Regulation Of Organ Morphogenesis Regulation Of Stress-activated MAPK Cascade Inner Ear Development Positive Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Neural Tube Development Mitochondrial Outer Membrane Permeabilization Positive Regulation Of MAP Kinase Activity Endothelial Cell Morphogenesis Tube Development Heart Morphogenesis Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Ear Development
Tagcloud ?		adopted alignment atp6 classical cndp2 constructed csde1 csfv dnaja1 dnaja4 fancl fever gaining gopc hemorrhage hnrnph1 indications interactive library ncbi ns2 pnma1 regarded suvec swine switching tmed4 umbilical y2h	butyrate demethylation derivation efficiency enhances greatly insights ips karyotypes klf4 microarrays naturally nutritional permeable piggybac pluripotency pluripotent refractory remarkable reprogramming retroviral sickle somatic stimulation substitutes supplement transgene transposon vectors
Tagcloud (Difference) ?		adopted alignment atp6 classical cndp2 constructed csde1 csfv dnaja1 dnaja4 fancl fever gaining gopc hemorrhage hnrnph1 indications interactive library ncbi ns2 pnma1 regarded suvec swine switching tmed4 umbilical y2h	butyrate demethylation derivation efficiency enhances greatly insights ips karyotypes klf4 microarrays naturally nutritional permeable piggybac pluripotency pluripotent refractory remarkable reprogramming retroviral sickle somatic stimulation substitutes supplement transgene transposon vectors
Tagcloud (Intersection) ?