LSM6 and LSM5

Number of citations of the paper that reports this interaction (PMID 15231747)
44

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (in vitro)

		LSM6	LSM5
Gene Name		LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)	LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasmic MRNA Processing Body Spliceosomal Complex U6 SnRNP Nucleolus Small Nucleolar Ribonucleoprotein Complex Cytosol Small Nuclear Ribonucleoprotein Complex U4/U6 X U5 Tri-snRNP Complex Extracellular Vesicular Exosome	Nucleus Spliceosomal Complex Cytosol
	Molecular Function	Protein Binding Poly(A) RNA Binding	RNA Binding Protein Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay MRNA Splicing, Via Spliceosome TRNA Processing RNA Splicing Gene Expression Maturation Of SSU-rRNA Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay	Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay MRNA Processing RNA Splicing Gene Expression Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay
Pathways		mRNA decay by 5' to 3' exoribonuclease Deadenylation-dependent mRNA decay	mRNA decay by 5' to 3' exoribonuclease Deadenylation-dependent mRNA decay
Drugs
Diseases
GWAS			Palmitic acid (16:0) plasma levels ( 23362303)
Protein-Protein Interactions		15 interactors: APP CLNS1A LSM1 LSM2 LSM3 LSM5 LSM7 LSM8 MCRS1 POLD2 SDCBP SMN1 SNRPD2 SNRPF TARDBP	11 interactors: EXOSC5 HNRNPD LSM1 LSM2 LSM3 LSM6 LSM7 LSM8 SMN1 SNRPE SNRPF
Entrez ID		11157	23658
HPRD ID		06286	06285
Ensembl ID		ENSG00000164167	ENSG00000106355
Uniprot IDs		P62312	Q9Y4Y9
PDB IDs
Enriched GO Terms of Interacting Partners?		MRNA Processing RNA Splicing MRNA Metabolic Process RNA Processing RNA Splicing, Via Transesterification Reactions Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic MRNA Splicing, Via Spliceosome Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Spliceosomal SnRNP Assembly Nitrogen Compound Metabolic Process Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process RNA Catabolic Process Ribonucleoprotein Complex Assembly Aromatic Compound Catabolic Process Ribonucleoprotein Complex Biogenesis Cellular Metabolic Process Histone MRNA Metabolic Process Cellular Macromolecule Catabolic Process NcRNA Metabolic Process Cellular Macromolecular Complex Assembly Cellular Component Assembly Spliceosomal Complex Assembly MRNA 3'-end Processing Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury RNA 3'-end Processing Positive Regulation Of Extracellular Vesicular Exosome Assembly Collateral Sprouting Axon Midline Choice Point Recognition Metabolic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Extracellular Vesicular Exosome Assembly Catabolic Process Axon Choice Point Recognition Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Neuron Remodeling Histone MRNA Catabolic Process 3'-UTR-mediated MRNA Stabilization Negative Regulation By Host Of Viral Transcription Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Substrate-dependent Cell Migration, Cell Extension	MRNA Metabolic Process RNA Splicing MRNA Processing RNA Splicing, Via Transesterification Reactions Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic RNA Processing MRNA Splicing, Via Spliceosome Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay RNA Catabolic Process Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process Aromatic Compound Catabolic Process RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Catabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Histone MRNA Metabolic Process Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Biogenesis Spliceosomal SnRNP Assembly NcRNA Metabolic Process Catabolic Process Ribonucleoprotein Complex Assembly Cellular Metabolic Process Termination Of RNA Polymerase II Transcription Spliceosomal Complex Assembly DNA-templated Transcription, Termination MRNA 3'-end Processing RNA 3'-end Processing RRNA Processing RRNA Metabolic Process Metabolic Process Cellular Macromolecular Complex Assembly Circadian Regulation Of Translation Ribosome Biogenesis Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA DNA Deamination Histone MRNA Catabolic Process RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Maturation Of SSU-rRNA Ribosomal Small Subunit Biogenesis Regulation Of MRNA Stability Regulation Of RNA Stability
Tagcloud ?		angles arrange assemble building heptameric heteroheptameric hexameric incorporate lsm1 lsm2 lsm23 lsm5 lsm57 lsm657 lsm7 monomers nonetheless plastic pockets preferences pull ring sme smf smg solved spliceosomal	angles arrange assemble building heptameric heteroheptameric hexameric incorporate lsm1 lsm2 lsm23 lsm57 lsm6 lsm657 lsm7 monomers nonetheless plastic pockets preferences pull ring sme smf smg solved spliceosomal
Tagcloud (Difference) ?
Tagcloud (Intersection) ?		angles arrange assemble building heptameric heteroheptameric hexameric incorporate lsm1 lsm2 lsm23 lsm5 lsm57 lsm6 lsm657 lsm7 monomers nonetheless plastic pockets preferences pull ring sme smf smg solved spliceosomal