ATPIF1 and UBQLN4

Number of citations of the paper that reports this interaction (PMID 16713569)
214

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ATPIF1	UBQLN4
Gene Name		ATPase inhibitory factor 1	ubiquilin 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Proton-transporting ATP Synthase Complex Cell Surface	Nucleus Cytoplasm Endoplasmic Reticulum Membrane Cytosol Nuclear Proteasome Complex Cytosolic Proteasome Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Enzyme Inhibitor Activity Calmodulin Binding ATPase Inhibitor Activity Protein Homodimerization Activity Angiostatin Binding ATPase Binding	Protein Binding Polyubiquitin Binding Identical Protein Binding
	Biological Process	Angiogenesis Negative Regulation Of Endothelial Cell Proliferation Generation Of Precursor Metabolites And Energy Heme Biosynthetic Process Erythrocyte Differentiation Negative Regulation Of Nucleotide Metabolic Process Protein Homooligomerization Protein Homotetramerization Negative Regulation Of Hydrolase Activity Reactive Oxygen Species Metabolic Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway	Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Pathways
Drugs
Diseases
GWAS			Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions		4 interactors: CHD3 GSK3B PIK3CA UBQLN4	157 interactors: ADAM33 ADPGK AGR2 ANKRD13D AREG ARL4C ATPIF1 ATXN1 BAG6 BPIFA1 C11orf49 C1orf94 C1QTNF1 CACNA1G CCDC107 CCDC134 CCDC136 CCDC14 CCDC33 CCL21 CD99 CDSN CEND1 COL8A1 COPB1 CPSF6 CRIPT CSTF2 CSTF2T CTSB CYB5R1 DAZAP2 DKK3 DMPK DNAJB11 DTX2 EAPP EDN1 EEF1A1 EFEMP2 ELF5 EPDR1 ERP27 ERP29 FA2H FGFBP1 FKBP2 FKBP7 FZD7 GABRD GDI1 GKAP1 GPX7 HAVCR1 HGS HK2 HSPA13 HSPA5 IGFBP6 IGHM IGLC1 IMMT IMPDH2 ITPRIPL1 KLHL26 KLHL42 LAT2 MDK MDM2 MIEF2 MIF4GD MLLT6 MOAP1 MYDGF NAE1 NME3 NOMO1 NOMO3 NOTCH2NL NPHP1 NPPA NXF1 OAT ORC5 PBXIP1 PCDH17 PCDH8 PDIA5 PDLIM7 PELI2 PICK1 PIN1 PIP4K2B PLA2G16 PMEPA1 PNMA1 PPIB PPIC PRL PRPF40A PSMD4 PTN PTPRN PTPRN2 QSOX1 RAD23A RAI2 RBM10 RIC8A RNF11 RNPS1 ROBO2 RPN1 RSRC2 RUNX1T1 RXRA SCAF1 SCG2 SCG5 SCMH1 SEMG1 SERPINE1 SERPINH1 SERPINI2 SMAD3 SMAD9 SMARCB1 SPAG8 SPINT1 SPP1 SRGN SRSF2 STAM2 STMN1 SUPT20H TFF1 TGFB1I1 TNFRSF14 TNRC6B TRAF2 TRIB2 TRIM32 UBQLN1 UBQLN2 UBR7 UNC119 UROS USMG5 VIP WAC YWHAQ ZBTB22 ZDHHC3 ZFPM2 ZG16 ZG16B ZNF205
Entrez ID		93974	56893
HPRD ID		16529	05670
Ensembl ID		ENSG00000130770	ENSG00000160803
Uniprot IDs		Q9UII2	B4DZF6 Q9NRR5
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of DNA Methylation Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Peptidyl-serine Phosphorylation Phosphatidylinositol-mediated Signaling Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Hypomethylation Of CpG Island Negative Regulation Of Type B Pancreatic Cell Development Superior Temporal Gyrus Development Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Regulation Of Proteasomal Protein Catabolic Process Re-entry Into Mitotic Cell Cycle Negative Regulation Of Neuron Maturation Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Fc-epsilon Receptor Signaling Pathway Hypermethylation Of CpG Island Insulin Receptor Signaling Pathway Via Phosphatidylinositol 3-kinase Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Fc Receptor Signaling Pathway Cellular Response To Interleukin-3 Regulation Of Developmental Growth Regulation Of Genetic Imprinting Regulation Of Neuron Maturation Negative Regulation Of Glycogen (starch) Synthase Activity Protein Localization To Microtubule Negative Regulation Of Dendrite Morphogenesis Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Cell Adhesion Negative Regulation Of NFAT Protein Import Into Nucleus Regulation Of Protein Catabolic Process Regulation Of Cellular Amino Acid Metabolic Process ER Overload Response Negative Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Glycogen Biosynthetic Process Negative Regulation Of Fibroblast Apoptotic Process Negative Regulation Of Muscle Hypertrophy Regulation Of Glycogen (starch) Synthase Activity Regulation Of Cellular Protein Metabolic Process Immune Response-regulating Signaling Pathway Positive Regulation Of Protein Export From Nucleus Regulation Of Type B Pancreatic Cell Development Negative Regulation Of Anoikis Regulation Of Cellular Ketone Metabolic Process Positive Regulation Of Peptidyl-threonine Phosphorylation Negative Regulation Of Dendrite Development Regulation Of Protein Metabolic Process	Regulation Of Cellular Process Response To Stress Positive Regulation Of Cellular Metabolic Process Response To Stimulus Signaling Signal Transduction Cell Communication Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Cellular Response To Stimulus Multicellular Organismal Development Positive Regulation Of Metabolic Process Regulation Of Cell Death Regulation Of Apoptotic Process Regulation Of Cell Proliferation Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Transport Organ Development Positive Regulation Of Mitochondrion Organization Regulation Of Cellular Localization Regulation Of Proteolysis Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Developmental Process Response To Organic Substance Tissue Development Regulation Of Metabolic Process Positive Regulation Of Gene Expression Anatomical Structure Development Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Protein Catabolic Process Regulation Of Signal Transduction Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Behavior Regulation Of Phosphorus Metabolic Process System Development Protein Peptidyl-prolyl Isomerization Regulation Of Signaling Negative Regulation Of Cell Proliferation Regulation Of Body Fluid Levels Regulation Of Chemotaxis Cell Surface Receptor Signaling Pathway Regulation Of Phosphorylation Cellular Localization Defense Response Regulation Of Mitochondrion Organization Extracellular Matrix Organization Extracellular Structure Organization Regulation Of Cellular Component Organization
Tagcloud ?		4alpha abcc3 accessible alu apoa4 apom canx elements employ femt1a genomics gstm4 hepatocyte hnf4alpha il32 ip6k2 junk microarrays nr2a1 originally pbms prlr prodh2 repeats sizeable socs2 superfamily tiggers ttr
Tagcloud (Difference) ?		4alpha abcc3 accessible alu apoa4 apom canx elements employ femt1a genomics gstm4 hepatocyte hnf4alpha il32 ip6k2 junk microarrays nr2a1 originally pbms prlr prodh2 repeats sizeable socs2 superfamily tiggers ttr
Tagcloud (Intersection) ?