RAB35 and MPHOSPH9

Data Source: HiPPIP (Novel)

		RAB35	MPHOSPH9
Name		RAB35, member RAS oncogene family	M-phase phosphoprotein 9
Structure			No pdb structure
GO Annotations	Cellular Component	Endosome Cytosol Plasma Membrane Clathrin-coated Pit Endosome Membrane Membrane Clathrin-coated Vesicle Clathrin-coated Endocytic Vesicle Membrane Cell Projection Membrane Cytoplasmic Vesicle Melanosome Intercellular Bridge Clathrin-coated Endocytic Vesicle Recycling Endosome Membrane Extracellular Exosome	Golgi Membrane Cytoplasm Golgi Apparatus Centrosome Centriole Cytoskeleton Membrane
	Molecular Function	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Phosphatidylinositol-4,5-bisphosphate Binding Hydrolase Activity GDP Binding Metal Ion Binding	Protein Binding
	Biological Process	Mitotic Cytokinesis Intracellular Protein Localization Protein Transport Endosomal Transport Antigen Processing And Presentation Neuron Projection Development Endocytic Recycling Rab Protein Signal Transduction Protein Localization To Endosome Plasma Membrane To Endosome Transport Cellular Response To Nerve Growth Factor Stimulus	Negative Regulation Of Cilium Assembly
Pathways		TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	None
GWAS		Heel bone mineral density ( 30598549 )	A body shape index ( 34021172 ) Albumin-globulin ratio ( 29403010 ) Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028 ) Autism spectrum disorder or schizophrenia ( 28540026 ) Brain morphology (MOSTest) ( 32665545 ) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203 ) Educational attainment ( 25201988 ) Hip circumference adjusted for BMI ( 34021172 ) Intelligence (MTAG) ( 29326435 ) Multiple sclerosis ( 19525953 ) Plasma anti-thyroglobulin levels ( 29678681 ) Platelet count ( 27863252 32888494 ) Plateletcrit ( 27863252 ) Schizophrenia ( 23974872 30285260 29483656 28991256 25056061 ) Tourette syndrome ( 30818990 ) Type 2 diabetes ( 30297969 29632382 24509480 ) Type 2 diabetes (adjusted for BMI) ( 29632382 ) Venous thromboembolism ( 31420334 ) Waist circumference adjusted for body mass index ( 34021172 ) Waist-hip index ( 34021172 ) Waist-to-hip ratio adjusted for BMI ( 34021172 )
Novel Interactors		1 novel interactors: MPHOSPH9	15 novel interactors: ACACA ALPP ANXA11 ARF5 ATP6V0A2 CABP1 GSK3A HCAR3 KNTC1 MLEC MRPL19 RAB35 SNRNP35 SRSF9 TRA2A
Interacting Genes		11 interacting genes: APP CALCOCO2 CBR3 DENND1B GNPAT IDH3B PTPRS TBPL1 TRIM54 USP32 WDCP	3 interacting genes: SVIL YWHAG YWHAZ
Entrez ID		11021	10198
HPRD ID		05010	12022
Ensembl ID		ENSG00000111737	ENSG00000051825
Uniprot IDs		Q15286	Q99550
PDB IDs		3TW8 6EKK 6IF2 6IF3	Not available