ABI3BP and ABI3

Number of citations of the paper that reports this interaction (PubMedID 11501947)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ABI3BP	ABI3
Description		ABI family member 3 binding protein	ABI family member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Extracellular Matrix	Cytoplasm Postsynaptic Density Membrane Lamellipodium SCAR Complex Dendritic Spine Dendritic Shaft Postsynapse Actin-based Cell Projection Glutamatergic Synapse
	Molecular Function	Extracellular Matrix Structural Constituent	Protein Binding Signaling Adaptor Activity Identical Protein Binding Actin Filament Binding
	Biological Process	Positive Regulation Of Cell-substrate Adhesion Extracellular Matrix Organization	Neuron Migration Defense Response To Tumor Cell Negative Regulation Of Lamellipodium Assembly Peptidyl-tyrosine Phosphorylation Actin Cytoskeleton Organization Regulation Of Cell Migration Cell Projection Morphogenesis Regulation Of Dendritic Spine Morphogenesis Modification Of Postsynaptic Actin Cytoskeleton Regulation Of Postsynaptic Density Assembly Negative Regulation Of Ruffle Assembly Negative Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Cellular Senescence
Pathways
Drugs
Diseases
GWAS		Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced) ( 24236485) Alcohol dependence ( 26365420) Asthma (childhood onset) ( 23829686) Carotid plaque burden ( 28282560) Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Gut microbiota relative abundance (Faecalibacterium) ( 33208821) Joint mobility (Beighton score) ( 27182965) Multiple sclerosis ( 31604244) Optic disc area ( 25631615 28073927) Optic disc size ( 31809533) Post bronchodilator FEV1 in COPD ( 26634245) Refractive error ( 32231278) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)	Alzheimer's disease (late onset) ( 28714976) Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Asthma ( 31619474) Family history of Alzheimer's disease ( 30617256) Prostate cancer ( 23535732) Refractive error ( 32231278)
Interacting Genes		6 interacting genes: ABI3 CBX1 FZD5 GOT1 GRB2 MBNL1	77 interacting genes: ABI2 ABI3BP ACTN3 AGTR1 ARHGAP9 ARMC7 BAIAP2L2 BFSP2 BLOC1S5 CENPQ CEP170P1 CEP44 CYFIP2 DESI1 DTNB DTNBP1 EIF3H EIF3M EMILIN1 ENAH EVL FAM124B FARSA FBF1 GNG13 GOLM1 GRB2 HOMER1 HOMER2 HOMER3 IFT20 IHO1 KANK2 KIAA0408 KIFC3 KLC3 KLC4 KRT13 KRT14 KRT15 KRT24 KRT28 KRT31 KRT35 KRT36 KRT38 MAGEA12 MED29 MIS18A MRFAP1 MRFAP1L1 NCK2 NDEL1 NHSL2 NUP58 OIP5 PAK1 PAK2 PSMA1 RUFY3 RUNX1T1 SH3BP1 SMARCD1 SNAP23 SOS1 STX1A STX2 SUFU TMEM147 TRAF4 TXN2 VARS2 VASP WAS WASF1 WASF2 WASHC1
Entrez ID		25890	51225
HPRD ID		09380	05900
Ensembl ID		ENSG00000154175	ENSG00000108798
Uniprot IDs		D3YTG3 F6R962 H7C556 Q7Z7G0	Q9P2A4
PDB IDs
Enriched GO Terms of Interacting Partners?		Branching Involved In Labyrinthine Layer Morphogenesis L-cysteine Transaminase Activity L-glutamate Catabolic Process To Aspartate L-aspartate:2-oxoglutarate Aminotransferase Activity Aspartate Biosynthetic Process Phosphatidylserine Decarboxylase Activity L-glutamate Biosynthetic Process Embryonic Morphogenesis Guanyl-nucleotide Exchange Factor Adaptor Activity Anatomical Structure Morphogenesis Grb2-EGFR Complex Oxaloacetate Metabolic Process Transdifferentiation Carboxylic Acid Binding L-aspartate Catabolic Process Glutamate Biosynthetic Process L-glutamate Catabolic Process Malate-aspartate Shuttle Response To Transition Metal Nanoparticle Glycerol Biosynthetic Process Negative Regulation Of Mitochondrial Depolarization Aspartate Metabolic Process Morphogenesis Of A Branching Structure Morphogenesis Of A Branching Epithelium Regulation Of Lymphocyte Mediated Immunity Neurotrophin TRKA Receptor Binding Chorionic Trophoblast Cell Differentiation Regulation Of Chorionic Trophoblast Cell Proliferation Intestinal Epithelial Cell Maturation Glandular Epithelial Cell Maturation Syncytiotrophoblast Cell Differentiation Involved In Labyrinthine Layer Development Spemann Organizer Formation Post-embryonic Camera-type Eye Development Male Pronucleus Actin-based Cell Projection Negative Regulation Of Lamellipodium Assembly Negative Regulation Of Ruffle Assembly Regulation Of Cell Junction Assembly Anterior/posterior Axis Specification, Embryo Columnar/cuboidal Epithelial Cell Maturation Synapse Organization Female Pronucleus Defense Response To Tumor Cell Negative Regulation Of Collagen Biosynthetic Process Negative Regulation Of Cytosolic Calcium Ion Concentration Glycerol Metabolic Process Cell Differentiation Morphogenesis Of An Epithelium Insulin Receptor Substrate Binding Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity	Supramolecular Fiber Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Regulation Of Actin Filament Organization Intermediate Filament Organization Structural Constituent Of Skin Epidermis Keratin Filament Regulation Of Actin Cytoskeleton Organization Cytoskeleton Regulation Of Actin Filament-based Process Regulation Of Supramolecular Fiber Organization Structural Molecule Activity SH3 Domain Binding Anatomical Structure Morphogenesis Morphogenesis Of An Epithelium Intermediate Filament Cytoskeleton Organization Regulation Of Cytoskeleton Organization Lamellipodium Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Actin Filament Organization Tissue Morphogenesis Positive Regulation Of Supramolecular Fiber Organization G Protein-coupled Glutamate Receptor Binding SCAR Complex Positive Regulation Of Cytoskeleton Organization Organelle Organization Actin Polymerization Or Depolymerization Cytosol Regulation Of Actin Filament Polymerization Epithelial Cell Differentiation Anchoring Junction Regulation Of Cellular Component Size Protein Binding Positive Regulation Of Protein Polymerization Positive Regulation Of Actin Filament Polymerization Cellular Component Assembly Positive Regulation Of Cellular Component Biogenesis Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Regulation Of Arp2/3 Complex-mediated Actin Nucleation Profilin Binding Developmental Process Regulation Of Organelle Organization Regulation Of Actin Nucleation Postsynaptic Density Vesicle Membrane Cell Projection Organization Positive Regulation Of Actin Nucleation Regulation Of Store-operated Calcium Entry
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?